CAS 526-08-9
:Sulfaphenazole
Description:
Sulfaphenazole is a sulfonamide antibiotic that belongs to the class of compounds known as sulfa drugs. It is characterized by its ability to inhibit bacterial growth by interfering with the synthesis of folic acid, which is essential for bacterial metabolism. The chemical structure of sulfaphenazole features a sulfonamide group attached to a phenyl ring, which contributes to its antibacterial properties. It is typically used in the treatment of urinary tract infections and other bacterial infections. Sulfaphenazole is known for its relatively low solubility in water, which can affect its bioavailability and therapeutic efficacy. The compound is usually administered orally and is metabolized in the liver, with its metabolites excreted primarily through the urine. Additionally, sulfaphenazole may exhibit side effects, including allergic reactions and hematological disorders, which necessitate careful monitoring during treatment. Overall, sulfaphenazole remains an important agent in the arsenal of antibiotics, particularly in specific clinical scenarios where its use is warranted.
Formula:C15H14N4O2S
InChI:InChI=1S/C15H14N4O2S/c16-12-6-8-14(9-7-12)22(20,21)18-15-10-11-17-19(15)13-4-2-1-3-5-13/h1-11,18H,16H2
InChI key:InChIKey=QWCJHSGMANYXCW-UHFFFAOYSA-N
SMILES:N(S(=O)(=O)C1=CC=C(N)C=C1)C=2N(N=CC2)C3=CC=CC=C3
Synonyms:- 1-Phenyl-5-sulfanilamidopyrazole
- 2-Phenyl-3-sulfanilamidopyrazole
- 3-(p-Aminobenzenesulfonamido)-2-phenylpyrazole
- 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide
- 5-Sulfanilamido-1-phenylpyrazole
- Benzenesulfonamide, 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)-
- Depocid
- Depotsulfonamide
- Eftolon
- Firmazolo
- Inamil
- Isarol
- Isarol V
- Merian
- Microtan pirazolo
- N1-(1-phenylpyrazol-5-yl)sulphanilamide
- N<sup>1</sup>-(1-Phenylpyrazol-5-yl)sulfanilamide
- Orisul
- Orisulf
- Paidazolo
- Plisulfan
- Raziosulfa
- Sulfabid
- Sulfanilamide, N<sup>1</sup>-(1-phenylpyrazol-5-yl)-
- Sulfaphenazol
- Sulfaphenazon
- Sulfaphenylpyrazole
- Sulphaphenazole
- See more synonyms
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Found 15 products.
Sulfaphenazole
CAS:Formula:C15H14N4O2SPurity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:314.364-Amino-N-(1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide
CAS:4-Amino-N-(1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamideFormula:C15H14N4O2SPurity:99%Color and Shape: pale yellow solidMolecular weight:314.37g/molMinistry of Agriculture Veterinary Drug Mixture 348 10 µg/mL in Acetonitrile:Water
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Color and Shape:MixtureSulfaphenazole
CAS:Formula:C15H14N4O2SPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:314.36Sulfaphenazole 100 µg/mL in Acetonitrile
CAS:Formula:C15H14N4O2SColor and Shape:Single SolutionMolecular weight:314.36Sulfaphenazole
CAS:<p>Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for</p>Formula:C15H14N4O2SPurity:97.53% - 99.67%Color and Shape:SolidMolecular weight:314.36Sulfaphenazole-d4
CAS:Controlled Product<p>Applications Sulfaphenazole-d4 is the labelled analogue of Sulfaphenazole (S689020), that is used as an inhibitor for mammalian CYP2C9, an enzyme of the cytochrome P450 family, allowing for pharmacological application.Sulfaphenazole can help protect against ischemia-reperfusion, and resulting tissue damage through inhibition of CYP2C9.<br>References Vestergren, A.L.S. et al.: Mol. Biol. Rep., 39, 6867 (2012); Huang, C. et al.: Amer. J. Phys., 298, H570 (2010);<br></p>Formula:C15H10D4N4O2SColor and Shape:Off-WhiteMolecular weight:318.39Sulfaphenazole
CAS:Controlled Product<p>Applications Sulfaphenazole is used as an inhibitor for mammalian CYP2C9, an enzyme of the cytochrome P450 family allowing for pharmacological application.Sulfaphenazole can help protect against ischemia-reperfusion, and resulting tissue damage by inhibition of CYP2C9.<br>References Vestergren, A.L.S. et al.: Mol. Biol. Rep., 39, 6867 (2012); Huang, C. et al.: Amer. J. Phys., 298, H570 (2010);<br></p>Formula:C15H14N4O2SColor and Shape:Off WhiteMolecular weight:314.36Sulfaphenazole
CAS:<p>Sulfaphenazole is an antibacterial drug that belongs to the group of sulfonamides. It inhibits bacterial growth by competitively inhibiting the synthesis of folic acid in bacteria, which is required for protein synthesis and cell division. Sulfaphenazole has been shown to inhibit a number of enzymes, such as P450 activity, catalysed by cytochrome P450 enzymes. It also inhibits the mitochondrial membrane potential, which is vital for oxidative phosphorylation. Sulfaphenazole has shown inhibitory properties against kidney fibrosis and may be useful in treating kidney failure due to diabetes or hypertension. This drug is also used as an oral hypoglycaemic agent and to treat complications from myocardial infarcts such as autophagy.</p>Formula:C15H14N4O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:314.36 g/mol4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide
CAS:Formula:C15H14N4O2SPurity:95.0%Color and Shape:SolidMolecular weight:314.36
