CAS 526-31-8

N-Methyl-L-tryptophan

Description:

N-Methyl-L-tryptophan is an amino acid derivative and a structural analog of the essential amino acid L-tryptophan. It is characterized by the presence of a methyl group attached to the nitrogen atom of the indole side chain, which alters its biochemical properties. This compound is often studied for its role in various biological processes, including its potential effects on serotonin metabolism and its involvement in immune response modulation. N-Methyl-L-tryptophan has been investigated for its potential therapeutic applications, particularly in the context of cancer immunotherapy, as it can influence tryptophan catabolism via the kynurenine pathway. The compound is typically a white to off-white crystalline solid and is soluble in polar solvents. Its molecular structure contributes to its ability to interact with biological systems, making it a subject of interest in pharmacological research. As with many amino acid derivatives, its properties can be influenced by factors such as pH and temperature, which are important considerations in experimental settings.

Formula: C₁₂H₁₄N₂O₂

InChI: InChI=1S/C12H14N2O2/c1-13-11(12(15)16)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,13-14H,6H2,1H3,(H,15,16)/t11-/m0/s1

InChI key: InChIKey=CZCIKBSVHDNIDH-NSHDSACASA-N

SMILES: C([C@@H](C(O)=O)NC)C=1C=2C(NC1)=CC=CC2

Synonyms:

• (2S)-3-(1H-Indol-3-yl)-2-(methylammonio)propanoate
• (2S)-3-(1H-Indol-3-yl)-2-(methylazaniumyl)propanoate
• (S)-3-(1H-Indol-3-yl)-2-methylaminopropionic acid
• <span class="text-smallcaps">L</span>-(+)-Abrine
• <span class="text-smallcaps">L</span>-N-Methyltryptophan
• <span class="text-smallcaps">L</span>-Tryptophan, N-methyl-
• Abrine
• Abrine (amino acid)
• H-N-Me-Trp-OH
• L-Abrine
• N-Methyl-<span class="text-smallcaps">L</span>-tryptophan
• N-Methyltryptophan
• N-α-Methyl-<span class="text-smallcaps">L</span>-tryptophan
• Nplc 0233
• Tryptophan, N-methyl-, <span class="text-smallcaps">L</span>-
• Tryptophan, N-methyl-, L-
• N-Methyl-L-tryptophan

N-Me-Trp-OH

CAS: 526-31-8

Bachem ID: 4026253.

Formula: C₁₂H₁₄N₂O₂

Purity: > 99%

Color and Shape: Whitish Powder

Molecular weight: 218.26

Ref: 01-4026253

L-(+)-Abrine

CAS: 526-31-8

Formula: C₁₂H₁₄N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 218.2518

Ref: IN-DA003R70

L-Abrine

CAS: 526-31-8

Molecular weight: 218.25

Ref: 7W-GM8246

L-(+)-Abrine

CAS: 526-31-8

L-(+)-Abrine

Purity: ≥95%

Molecular weight: 218.25g/mol

Ref: 54-BUP17464

L-Abrine

CAS: 526-31-8

L-Abrine

Purity: ≥98%

Ref: 54-OR4400

Abrine

CAS: 526-31-8

Formula: C₁₂H₁₄N₂O₂

Purity: 95%~99%

Molecular weight: 218.256

Ref: BP-BP0112

L-Abrine

Controlled Product

CAS: 526-31-8

Applications L-Abrine is an indoleamino acid that displays radical scavenging and antioxidant properties.
References Yang, M., et al.: Food. Funct., 5, 2268 (2014);

Formula: C₁₂H₁₄N₂O₂

Color and Shape: Off-White

Molecular weight: 218.2518

Ref: TR-A109070

N-Methyl-L-tryptophan

CAS: 526-31-8

Purity: ≥98%(HPLC)

Molecular weight: 218.2559967

Ref: 10-F862820

L-Abrine

CAS: 526-31-8

L-Abrine is a plant toxin that belongs to the group of abrinoids. It is a chiral molecule and can exist as an L-form or D-form. The L-form is used in some analytical methods, such as gas chromatography, while the D-form is used in medical purposes. L-Abrine has been shown to have anti-HIV effects by inhibiting reverse transcriptase and deoxyribonuclease activity. It has also been shown to inhibit colony stimulating factor production and decrease bacterial growth in vitro. L-Abrine inhibits the replication of bacteria by binding to adenylate cyclase and blocking the enzyme's ability to synthesize cAMP from ATP. This inhibition prevents protein synthesis, leading to cell death.

Formula: C₁₂H₁₄N₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 218.25 g/mol

Ref: 3D-FM52417

L-(+)-Abrine

CAS: 526-31-8

L-(+)-Abrine (L-N-Methyltryptophan) is a toxic protein found in the jequirity seed.,can be used as a biomarker for abrin exposure.

Formula: C₁₂H₁₄N₂O₂

Purity: 98.71% - ≥95%

Color and Shape: White Powder

Molecular weight: 218.25

Ref: TM-T5718