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CAS 526-36-3

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Xylometazoline

Description:
Xylometazoline is a sympathomimetic agent primarily used as a topical nasal decongestant. It belongs to the imidazoline class of compounds and is commonly found in over-the-counter nasal sprays and drops. The substance works by stimulating alpha-adrenergic receptors in the nasal mucosa, leading to vasoconstriction and a subsequent reduction in nasal congestion. Xylometazoline is characterized by its rapid onset of action, typically providing relief within minutes, and its effects can last for several hours. It is generally well-tolerated, but prolonged use can lead to rebound congestion, a condition known as rhinitis medicamentosa. The chemical structure of xylometazoline includes a benzene ring and an imidazoline moiety, contributing to its pharmacological properties. It is important to use xylometazoline as directed to minimize potential side effects, which may include local irritation or dryness of the nasal mucosa. As with any medication, individuals should consult healthcare professionals before use, especially if they have underlying health conditions or are taking other medications.
Formula:C16H24N2
InChI:InChI=1S/C16H24N2/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15/h8-9H,6-7,10H2,1-5H3,(H,17,18)
InChI key:InChIKey=HUCJFAOMUPXHDK-UHFFFAOYSA-N
SMILES:C(C1=C(C)C=C(C(C)(C)C)C=C1C)C=2NCCN2
Synonyms:
  • 1H-Imidazole, 2-((4-(1,1-dimethylethyl)-2,6-dimethylphenyl)methyl)-4,5-dihydro- (9CI)
  • 1H-Imidazole, 2-[[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-
  • 2-(4-tert-Butyl-2,6-dimethyl-benzyl)-4,5-dihydro-1H-imidazole
  • 2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline
  • 2-(4-tert-butyl-2,6-dimethylbenzyl)-4,5-dihydro-1H-imidazol-3-ium
  • 2-(4-tert-butyl-2,6-dimethylbenzyl)-4,5-dihydro-1H-imidazole
  • 2-(4′-tert-Butyl-2′,6′-dimethylbenzyl)imidazoline
  • 2-(4′-tert-Butyl-2′,6′-dimethylphenylmethyl)imidazoline
  • 2-Imidazoline, 2-(4-tert-butyl-2,6-dimethylbenzyl)-
  • 2-[(4-tert-Butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole
  • See more synonyms
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