CAS 52899-09-9

L-Prolyl-L-valine

Description:

L-Prolyl-L-valine, with the CAS number 52899-09-9, is a dipeptide composed of the amino acids proline and valine. This compound is characterized by its unique structure, which includes a cyclic structure from proline that contributes to its conformational stability. L-Prolyl-L-valine is typically white to off-white in appearance and is soluble in water, making it suitable for various biochemical applications. It is often studied for its potential roles in peptide synthesis and as a building block in the development of pharmaceuticals. The presence of proline in its structure can influence the peptide's folding and stability, while valine contributes to hydrophobic interactions. This dipeptide may also exhibit biological activity, including potential effects on protein synthesis and cellular signaling pathways. Overall, L-Prolyl-L-valine serves as an important compound in both research and potential therapeutic applications, particularly in the fields of biochemistry and medicinal chemistry.

Formula: C₁₀H₁₈N₂O₃

InChI: InChI=1S/C10H18N2O3/c1-6(2)8(10(14)15)12-9(13)7-4-3-5-11-7/h6-8,11H,3-5H2,1-2H3,(H,12,13)(H,14,15)/t7-,8-/m0/s1

InChI key: InChIKey=AWJGUZSYVIVZGP-YUMQZZPRSA-N

SMILES: [C@H](NC(=O)[C@@H]1CCCN1)([C@@H](C)C)C(O)=O

Synonyms:

• 107: PN: WO2006024694 SEQID: 107 claimed protein
• 147: PN: EP2161028 PAGE: 10 claimed protein
• 34: PN: WO2014102101 SEQID: 334 claimed protein
• 34: PN: WO2014102104 SEQID: 133 claimed protein
• <span class="text-smallcaps">L</smallcap>-Prolyl-<smallcap>L</span>-valine
• <span class="text-smallcaps">L</smallcap>-Valine, <smallcap>L</span>-prolyl-
• <span class="text-smallcaps">L</smallcap>-Valine, N-<smallcap>L</span>-prolyl-
• L-Propyl-L-valine
• N-propyl-L-valine
• NSC 319054
• Prolyl-valine
• Prolylvaline
• Valine, N-<span class="text-smallcaps">L</span>-prolyl-
• L-Valine, L-prolyl-
• L-Prolyl-L-valine
• L-Valine, N-L-prolyl-

H-Pro-Val-OH

CAS: 52899-09-9

Substrate for human kidney prolinase (prolyl dipeptidase).

Formula: C₁₀H₁₈N₂O₃

Purity: > 99%

Color and Shape: White Crystalline Powder

Molecular weight: 214.27

Ref: 01-4007540

H-Pro-Val-OH

CAS: 52899-09-9

Formula: C₁₀H₁₈N₂O₃

Purity: 97%

Molecular weight: 214.2615

Ref: IN-DA00DEPX

H-Pro-Val-OH

CAS: 52899-09-9

H-Pro-Val-OH

Purity: 97%

Molecular weight: 214.26g/mol

Ref: 54-OR1056050

H-Pro-Val-OH

CAS: 52899-09-9

H-Pro-Val-OH is an amide that is used to treat renal disorders by inhibiting leukocyte elastase. It has been shown to be a potent inhibitor of serine proteases, including chymotrypsin and trypsin. H-Pro-Val-OH binds to the active site on serine proteases and blocks the release of peptides from the enzyme. The binding constant for H-Pro-Val-OH with chymotrypsin was found to be in the range of 3 x 10 M, which is significantly higher than that for other amides. In addition, H-Pro-Val-OH inhibits cytolysis by lysosomal enzymes and protects against liver injury caused by chronic liver disease. This drug also shows low molecular weight and high water solubility, making it effective in treating acute hepatitis.

Formula: C₁₀H₁₈N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 214.26 g/mol

Ref: 3D-FP108165