CymitQuimica logo

CAS 53-84-9

:

NAD

Description:
NAD, or nicotinamide adenine dinucleotide, is a crucial coenzyme found in all living cells, playing a vital role in metabolic processes. It exists in two forms: oxidized (NAD+) and reduced (NADH). NAD+ is essential for redox reactions, facilitating the transfer of electrons in cellular respiration and energy production. It is involved in various biochemical pathways, including glycolysis, the citric acid cycle, and oxidative phosphorylation. Additionally, NAD+ serves as a substrate for several enzymes, including dehydrogenases, and is important for DNA repair and signaling. The substance is a dinucleotide composed of two nucleotides joined by their phosphate groups, with one nucleotide containing an adenine base and the other containing a nicotinamide base. NAD is soluble in water and has a relatively low molecular weight. Its role in cellular metabolism and energy transfer makes it a critical component in maintaining cellular health and function. Due to its importance, NAD and its derivatives are often studied in the context of aging, metabolic disorders, and various diseases.
Formula:C21H27N7O14P2
InChI:InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
InChI key:InChIKey=BAWFJGJZGIEFAR-NNYOXOHSSA-N
SMILES:O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)[N+]=5C=C(C(N)=O)C=CC5)(=O)[O-])(=O)O)[C@H]1O
Synonyms:
  • Adenine-nicotinamide dinucleotide
  • Adenosine 5'-(trihydrogen diphosphate), 5'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium hydroxide, inner salt
  • Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium hydroxide, inner salt
  • Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, inner salt
  • Adenosine 5′-(trihydrogen diphosphate), P′→5′-ester with 3-(aminocarbonyl)-1-β-<span class="text-smallcaps">D</span>-ribofuranosylpyridinium hydroxide, inner salt
  • Adenosine 5′-(trihydrogen diphosphate), P′→5′-ester with 3-(aminocarbonyl)-1-β-<span class="text-smallcaps">D</span>-ribofuranosylpyridinium, inner salt
  • Beta-Dpn
  • Co-I
  • Codehydrase I
  • Codehydrogenase I
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.Found 22 products.
  • β-Nicotinamide Adenine Dinucleotide
    Fluorochem
    + Info

    β-Nicotinamide Adenine Dinucleotide

    CAS:
    Purity:95+%
    Color and Shape:Solid
    Molecular weight:663.109

    Ref: 10-F545316

    5g
    32.00€
    10g
    43.00€
    100g
    338.00€
  • β-Nicotinamide Adenine Dinucleotide Sodium Salt Hydrate
    TRC
    + Info

    β-Nicotinamide Adenine Dinucleotide Sodium Salt Hydrate

    Controlled Product
    CAS:

    Stability Light Sensitive
    Applications β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.
    References Dudev, T. et al.: J. Am. Chem. Soc., 132, 16533 (2010); Kerbey, A. et al.: Biochem. J., 154, 327 (1976); Lahiri, S.D. et al.: ACS Chem. Biol., 7, 571 (2012);

    Formula:C21H26N7O14P2·Na·xH2O
    Purity:>85%
    Color and Shape:Neat
    Molecular weight:685.41

    Ref: TR-N407775

    100mg
    145.00€
    1g
    177.00€
    25g
    777.00€