CAS 53-84-9

NAD

Description:

NAD, or nicotinamide adenine dinucleotide, is a crucial coenzyme found in all living cells, playing a vital role in metabolic processes. It exists in two forms: oxidized (NAD+) and reduced (NADH). NAD+ is essential for redox reactions, facilitating the transfer of electrons in cellular respiration and energy production. It is involved in various biochemical pathways, including glycolysis, the citric acid cycle, and oxidative phosphorylation. Additionally, NAD+ serves as a substrate for several enzymes, including dehydrogenases, and is important for DNA repair and signaling. The substance is a dinucleotide composed of two nucleotides joined by their phosphate groups, with one nucleotide containing an adenine base and the other containing a nicotinamide base. NAD is soluble in water and has a relatively low molecular weight. Its role in cellular metabolism and energy transfer makes it a critical component in maintaining cellular health and function. Due to its importance, NAD and its derivatives are often studied in the context of aging, metabolic disorders, and various diseases.

Formula:C₂₁H₂₇N₇O₁₄P₂

InChI:InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChI key:InChIKey=BAWFJGJZGIEFAR-NNYOXOHSSA-N

SMILES:O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)[N+]=5C=C(C(N)=O)C=CC5)(=O)[O-])(=O)O)[C@H]1O

Synonyms:

Adenine-nicotinamide dinucleotide
Adenosine 5'-(trihydrogen diphosphate), 5'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium hydroxide, inner salt
Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium hydroxide, inner salt
Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, inner salt
Adenosine 5′-(trihydrogen diphosphate), P′→5′-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium hydroxide, inner salt
Adenosine 5′-(trihydrogen diphosphate), P′→5′-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, inner salt
Beta-Dpn
Co-I
Codehydrase I
Codehydrogenase I
Coenzyme I
Cozymase
Cozymase I
DPN
Diphosphopyridine nucleotide
Enzopride
NAD
NAD+
Nadid
Nadida
Nadide
Nicotinamide adenine dinucleotide
Nsc 20272
Oxidized diphosphopyridine nucleotide
Pyridinium, 3-carbamoyl-1-β-D-ribofuranosyl-, hydroxide, 5′→5′-ester with adenosine 5′-(trihydrogen pyrophosphate), inner salt
Pyridinium, 3-carbamoyl-1-β-D-ribofuranosyl-, hydroxide, 5'→5'-ester with adenosine 5'-(trihydrogen pyrophosphate), inner salt
[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl] phosphate
[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphate
beta-Diphosphopyridine nucleotide
beta-Nicotinamide adenine dinucleotide trihydrate
β-Diphosphopyridine nucleotide
β-NAD
β-NAD+
β-Nicotinamide Adenine Dinuclotide
β-Nicotinamide adenine dinucleotide
β-Nicotinamide adenine dinucleotide hydrate
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