CAS 5300-03-8
:9-cis-Retinoic acid
Description:
9-cis-Retinoic acid, also known as 9-cis-retinoate, is a derivative of vitamin A and plays a crucial role in various biological processes, particularly in vision and cellular differentiation. It is characterized by its unsaturated hydrocarbon structure, which includes a conjugated system of double bonds that contributes to its biological activity. This compound is a potent ligand for retinoic acid receptors (RARs), influencing gene expression and cellular functions. 9-cis-Retinoic acid is known for its ability to modulate the growth and differentiation of epithelial tissues and is involved in the regulation of embryonic development. It is soluble in organic solvents but has limited solubility in water. The compound is sensitive to light and air, necessitating careful handling and storage conditions to maintain its stability. Its therapeutic applications include potential uses in dermatology and oncology, particularly in the treatment of skin disorders and certain types of cancer. Overall, 9-cis-retinoic acid is a significant compound in both biochemistry and pharmacology, with ongoing research into its various roles and applications.
Formula:C20H28O2
InChI:InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
InChI key:InChIKey=SHGAZHPCJJPHSC-ZVCIMWCZSA-N
SMILES:C(=C/C(=C\C=C\C(=C\C(O)=O)\C)/C)\C=1C(C)(C)CCCC1C
Synonyms:- 9(Z)-Retinoic acid
- 9-Cis-Tretinoin
- Agn 192013
- Alitretinoin
- Alrt 1057
- Lg 100057
- Lgd 100057
- Lgd 1057
- NSC 659772
- Panretin
- Panretyn
- Panrexin
- Retinoic acid, 9-cis-
- Retinoic acid, cis-9,trans-13-
- Toctino
- 9-cis-Retinoic acid
- See more synonyms
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Found 12 products.
9-cis-Retinoic acid
CAS:<p>A high affinity ligand for the retinoid X receptor</p>Formula:C20H28O2Color and Shape:Pale yellow to yellow, PowderMolecular weight:300.449-cis-Retinoic Acid
CAS:<p>9-cis-Retinoic Acid (Alitretinoin) is a derivative of vitamin A. It is a RAR/RXR agonist and can be used to study advanced tumors.</p>Formula:C20H28O2Purity:98.32% - 99.34%Color and Shape:SolidMolecular weight:300.44Tretinoin EP Impurity D (Isotretinoin EP Impurity D, 9-cis-Retinoic Acid, Alitretinoin)
CAS:Formula:C20H28O2Color and Shape:Yellow SolidMolecular weight:300.44Tretinoin EP Impurity D-d5 (Isotretinoin EP Impurity D-d5, 9-cis-Retinoic Acid-d5, Alitretinoin-d5)
CAS:Formula:C20H23D5O2Molecular weight:305.479-cis-Retinoic Acid
CAS:Controlled Product<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An endogenous retinoic acid isomer, which is capable of binding to both retinoic acid receptors (RAR) and retinoid X receptors (RXR). A biologically active ligand for members of the RAR and RXR subfamilies, implying that it may play a critical role in regulating retinoid-responsive pathways.<br>References Heyman, R.A., et al.: Cell, 68, 397 (1992), Levin, A.A., et al.: Nature, 355, 359 (1992), Allenby, G., et al.: Proc. Natl. Acad. Sci. U.S.A., 90, 30 (1993)<br></p>Formula:C20H28O2Color and Shape:Light YellowMolecular weight:300.449-cis-Retinoic acid
CAS:Controlled Product<p>A natural metabolite of vitamin A. It is derived from all-trans retinoic acid, FR17921. It potently activates all isoforms of retinoic acid receptor (RAR) as well as retinoid X receptor (RXR) isoforms.</p>Formula:C20H28O2Purity:Min. 95%Color and Shape:PowderMolecular weight:300.44 g/mol
