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CAS 5300-03-8

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9-cis-Retinoic acid

Description:
9-cis-Retinoic acid, also known as 9-cis-retinoate, is a derivative of vitamin A and plays a crucial role in various biological processes, particularly in vision and cellular differentiation. It is characterized by its unsaturated hydrocarbon structure, which includes a conjugated system of double bonds that contributes to its biological activity. This compound is a potent ligand for retinoic acid receptors (RARs), influencing gene expression and cellular functions. 9-cis-Retinoic acid is known for its ability to modulate the growth and differentiation of epithelial tissues and is involved in the regulation of embryonic development. It is soluble in organic solvents but has limited solubility in water. The compound is sensitive to light and air, necessitating careful handling and storage conditions to maintain its stability. Its therapeutic applications include potential uses in dermatology and oncology, particularly in the treatment of skin disorders and certain types of cancer. Overall, 9-cis-retinoic acid is a significant compound in both biochemistry and pharmacology, with ongoing research into its various roles and applications.
Formula:C20H28O2
InChI:InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
InChI key:InChIKey=SHGAZHPCJJPHSC-ZVCIMWCZSA-N
SMILES:C(=C/C(=C\C=C\C(=C\C(O)=O)\C)/C)\C=1C(C)(C)CCCC1C
Synonyms:
  • 9(Z)-Retinoic acid
  • 9-Cis-Tretinoin
  • Agn 192013
  • Alitretinoin
  • Alrt 1057
  • Lg 100057
  • Lgd 100057
  • Lgd 1057
  • NSC 659772
  • Panretin
  • See more synonyms
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