CAS 53518-15-3

7-Amino-4-(trifluoromethyl)coumarin

Description:

7-Amino-4-(trifluoromethyl)coumarin is a synthetic organic compound belonging to the coumarin family, characterized by its distinct structural features, including a coumarin backbone with an amino group at the 7-position and a trifluoromethyl group at the 4-position. This compound typically exhibits a yellow to greenish-yellow fluorescence, making it useful in various applications such as fluorescent probes in biological imaging and as a dye in analytical chemistry. The presence of the trifluoromethyl group enhances its lipophilicity and stability, which can influence its reactivity and solubility in organic solvents. Additionally, the amino group can participate in hydrogen bonding, affecting its interaction with biological molecules. 7-Amino-4-(trifluoromethyl)coumarin is often utilized in research settings for its photophysical properties and potential applications in drug development and molecular biology. Safety data should be consulted for handling and usage, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₁₀H₆F₃NO₂

InChI: InChI=1/C10H6F3NO2/c11-10(12,13)7-4-9(15)16-8-3-5(14)1-2-6(7)8/h1-4H,14H2

InChI key: InChIKey=JBNOVHJXQSHGRL-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C=1C=2C(OC(=O)C1)=CC(N)=CC2

Synonyms:

• 2H-1-Benzopyran-2-one, 7-amino-4-(trifluoromethyl)-
• 4-(Trifluoromethyl)-7-aminocoumarin
• 7-Amino-4-(trifluoromethyl)-2H-1-benzopyran-2-one
• 7-Amino-4-(trifluoromethyl)coumarin
• Coumarin 151
• Coumarin 490
• NSC 337981
• Caspase 8 Fluorometric Substrate, IETD-AFC (FLICE, MASH, Mch5, N-acetyl-Asp-Glu-Val-Asp-AFC
• Coumarine151
• Coumarin 490. Coumarin 15
• 7-AMINO-4-(TRIFLUOROMETHYL)COUMARIN, 99+ %
• 7-AMINO-4-(TRIFLUOROMETHYL)COUMARIN, FOR FLUORESCENCE
• BUTTPARK 20\02-79
• AKOS B000459
• 7-amino-4-(trifluoromethyl)-2h-1-benzopyran-2-on
• Coumarin 151, laser grade, pure, 99%
• 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN
• 7-AMINO-4-TRIFLUOROMETHYL-CHROMEN-2-ONE
• 7-AMINO-4-(TRIFLUOROMETHYL)-2H-CHROMEN-2-ONE
• AFC
• 7-amino-4-(trifluoromethyl)-2-benzopyrone
• COUMARIN 151, 99%, LASER GRADE, PURE

7-Amino-4-(trifluoromethyl)coumarin, 97%

CAS: 53518-15-3

7-Amino-4-(trifluoromethyl)coumarin is used in the synthesis of substrates for the fluorometric assay of proteolytic enzymes in biological fluids. It is suitable as laser dye. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation a

Formula: C₁₀H₆F₃NO₂

Purity: 97%

Color and Shape: Yellow, Crystals or powder or crystalline powder

Molecular weight: 229.16

Ref: 02-A18400

7-Amino-4-(trifluoromethyl)-2H-chromen-2-one

CAS: 53518-15-3

Formula: C₁₀H₆F₃NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 229.1553

Ref: IN-DA003NCT

7-Amino-4-(trifluoromethyl)coumarin

CAS: 53518-15-3

7-Amino-4-(trifluoromethyl)coumarin

Purity: ≥95%

Molecular weight: 229.16g/mol

Ref: 54-BUP16865

7-Amino-4-(trifluoromethyl)coumarin

CAS: 53518-15-3

Formula: C₁₀H₆F₃NO₂

Purity: >97.0%(GC)(T)

Color and Shape: Light yellow to Yellow powder to crystal

Molecular weight: 229.16

Ref: 3B-A3747

7-Amino-4-(trifluoromethyl)coumarin

CAS: 53518-15-3

7-Amino-4-(trifluoromethyl)coumarin

Formula: C₁₀H₆F₃NO₂

Purity: 99%

Color and Shape: yellow flakes

Molecular weight: 229.16g/mol

Ref: 54-PC1100CF

7-Amino-4-trifluoromethylcoumarin

CAS: 53518-15-3

Formula: C₁₀H₆F₃NO₂

Molecular weight: 229.16

Ref: 7W-GT0896

7-Amino-4-(trifluoromethyl)coumarin

CAS: 53518-15-3

7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist.

Formula: C₁₀H₆F₃NO₂

Purity: 97.31% - 97.84%

Color and Shape: Yellow Powder

Molecular weight: 229.16

Ref: TM-TJS0341

7-Amino-4-(trifluoromethyl)coumarin

CAS: 53518-15-3

Formula: C₁₀H₆F₃NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 229.158

Ref: 10-F004029

7-Amino-4-(trifluoromethyl)coumarin

CAS: 53518-15-3

7-Amino-4-(trifluoromethyl)coumarin is a coumarin derivative that has been used as a fluorescence probe for the study of enzyme activities. It can be used as a potential biomarker for autoimmune diseases, and has also been shown to have tyrosine kinase domain binding activity. 7-Amino-4-(trifluoromethyl)coumarin can bind to the hydroxyl group in tyrosine residues with high affinity, and binds to the nitrogen atoms in protein kinases with low affinity. This compound is able to form intermolecular hydrogen bonds and steric interactions with peptide hormones.

Formula: C₁₀H₆F₃NO₂

Purity: Min. 95%

Molecular weight: 229.16 g/mol

Ref: 3D-FA74300

7-Amino-4-(trifluoromethyl)coumarin

CAS: 53518-15-3

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Formula: C₁₀H₆F₃NO₂

Purity: Min. 95%

Molecular weight: 229.16 g/mol

Ref: 3D-RA-10107