CAS 53609-64-6

N-Bis(2-hydroxypropyl)nitrosamine

Description:

N-Bis(2-hydroxypropyl)nitrosamine, with the CAS number 53609-64-6, is a chemical compound that belongs to the class of nitrosamines, which are known for their potential carcinogenic properties. This substance is characterized by the presence of two hydroxypropyl groups attached to a nitrosamine moiety, which contributes to its unique chemical behavior. It is typically a colorless to pale yellow liquid with a relatively low volatility. The compound is soluble in water and organic solvents, making it versatile in various chemical applications. N-Bis(2-hydroxypropyl)nitrosamine is primarily studied for its biological effects, particularly its role in the formation of DNA adducts, which can lead to mutations and cancer. Due to its potential health risks, it is important to handle this compound with care, following appropriate safety protocols to minimize exposure. Additionally, its use is often regulated in many countries due to the associated health concerns.

Formula: C₆H₁₄N₂O₃

InChI: InChI=1S/C6H14N2O3/c1-5(9)3-8(7-11)4-6(2)10/h5-6,9-10H,3-4H2,1-2H3

InChI key: InChIKey=MNIGYIKCFSPQRJ-UHFFFAOYSA-N

SMILES: N(CC(C)O)(CC(C)O)N=O

Synonyms:

• 1,1'-(Nitrosoimino)Dipropan-2-Ol
• 1,1′-(Nitrosoimino)bis[2-propanol]
• 2,2′-Dihydroxydipropylnitrosamine
• 2-Propanol, 1,1′-(nitrosoimino)bis-
• Di(2-hydroxypropyl)nitrosamine
• Diisopropanolnitrosamine
• N-Bis(2-hydroxypropyl)nitrosamine
• N-Nitrosobis(2-hydroxypropyl)amine
• Nitrosobis(2-hydroxypropyl)amine

1-[(2-hydroxypropyl)(nitroso)amino]propan-2-ol

CAS: 53609-64-6

Formula: C₆H₁₄N₂O₃

Purity: 95%

Color and Shape: Liquid

Molecular weight: 162.1870

Ref: IN-DA01CBRC

N-Bis(2-hydroxypropyl)nitrosamine

CAS: 53609-64-6

N-Bis(2-hydroxypropyl)nitrosamine

Purity: ≥98%

Molecular weight: 162.19g/mol

Ref: 54-BUP11836

Diisopropanolnitrosamine

CAS: 53609-64-6

Diisopropanolnitrosamine

Purity: 95%

Molecular weight: 162.19g/mol

Ref: 54-OR1024091

N-Nitroso Bis(2-Hydroxypropyl)amine

CAS: 53609-64-6

Formula: C₆H₁₄N₂O₃

Molecular weight: 162.19

Ref: 4Z-N-103078

N-Bis(2-hydroxypropyl)nitrosamine

CAS: 53609-64-6

N-Bis(2-hydroxypropyl)nitrosamine (DHPN) is a carcinogenic agent.

Formula: C₆H₁₄N₂O₃

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 162.19

Ref: TM-T19445

N-Nitrosobis(2-hydroxypropyl)amine

CAS: 53609-64-6

Formula: C₆H₁₄N₂O₃

Molecular weight: 162.19

Ref: ST-EA-CP-NIT031

N-Nitrosobis(2-hydroxypropyl)amine

Controlled Product

CAS: 53609-64-6

Applications It shows carcinogenicity in the duct cells.
References Chang, P., et al.: Environ. Mol. Mutagen, 41, 43 (2003), Prohaska, J., et al.: Exp. Biol. Med., 228, 959 (2003), Abe, K., et al.: Biomed. Res., 26, 187 (2005), Abe, M., et al.: J. Toxicol. Pathol., 19, 129 (2006),

Formula: C₆H₁₄N₂O₃

Color and Shape: Neat

Molecular weight: 162.19

Ref: TR-N525225

N-Nitrosobis(2-hydroxypropyl)amine

CAS: 53609-64-6

N-Nitrosobis(2-hydroxypropyl)amine is a polymerase chain reaction (PCR) enhancer that has been shown to be carcinogenic in experimental animals. It is used as a synthetic retinoid, which results in the conversion of thyroxine to triiodothyronine by the thyroid gland. N-Nitrosobis(2-hydroxypropyl)amine is also used as an experimental model for squamous cell carcinoma and tumors. It causes tumor development by inhibiting DNA synthesis and increasing cellular proliferation, which leads to liver lesions and carcinomas in animal models.

Formula: C₆H₁₄N₂O₃

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 162.19 g/mol

Ref: 3D-FN26357

2-Propanol, 1,1′-(nitrosoimino)bis-

CAS: 53609-64-6

Purity: 95%

Molecular weight: 162.1889954

Ref: 10-F864134

N-Nitrosobis(2-hydroxypropyl)amine-d12

Controlled Product

CAS: 53609-64-6

Applications Isotope labelled analog of N-Nitrosobis(2-hydroxypropyl)amine (N525225), a compound that exhibits carcinogenicity in duct cells.
References Chang, P., et al.: Environ. Mol. Mutagen, 41, 43 (2003), Prohaska, J., et al.: Exp. Biol. Med., 228, 959 (2003), Abe, K., et al.: Biomed. Res., 26, 187 (2005), Abe, M., et al.: J. Toxicol. Pathol., 19, 129 (2006),

Formula: C₆H₂D₁₂N₂O₃

Color and Shape: Neat

Molecular weight: 174.26

Ref: TR-N525227

Nitrosamine Mixture 251 1000 µg/mL in Ethanol

Controlled Product

CAS: 100-75-4, 1207995-62-7, 5336-53-8, 53609-64-6, 612-64-6, 69112-94-3, 86-30-6, 930-55-2, 937-40-6, 947-92-2, 98648-34-1, 997-95-5

Color and Shape: Mixture

Ref: 04-A50000251ET

N-Bis(2-hydroxypropyl)nitrosamine

CAS: 53609-64-6

Formula: C₆H₁₄N₂O₃

Color and Shape: Neat

Molecular weight: 162.19

Ref: 04-C10653650