![N2-[N-(N-acetylmuramoyl)-L-alanyl]-D-α-glutamine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F299649-n-acetylmuramyl-l-alanyl-d-isoglutamine.webp&w=3840&q=75)
CAS 53678-77-6
:N2-[N-(N-acetylmuramoyl)-L-alanyl]-D-α-glutamine
Description:
N2-[N-(N-acetylmuramoyl)-L-alanyl]-D-α-glutamine, commonly referred to as a peptidoglycan derivative, is a compound that plays a significant role in bacterial cell wall structure and function. This substance is characterized by its unique combination of amino acids and a muramoyl moiety, which is integral to the stability and integrity of bacterial cell walls. The presence of the N-acetylmuramoyl group contributes to its biological activity, particularly in interactions with the immune system. The compound exhibits properties typical of peptides, including solubility in water and potential reactivity with various biological molecules. Its structure allows it to participate in important biochemical pathways, particularly in the context of bacterial growth and immune response modulation. Additionally, due to its specific amino acid composition, it may exhibit unique binding affinities and enzymatic interactions, making it a subject of interest in microbiology and pharmacology. Understanding its characteristics can provide insights into bacterial physiology and the development of antimicrobial agents.
Formula:C19H32N4O11
InChI:InChI=1/C19H32N4O11/c1-7(17(30)23-10(16(20)29)4-5-12(26)27)21-18(31)8(2)33-15-13(22-9(3)25)19(32)34-11(6-24)14(15)28/h7-8,10-11,13-15,19,24,28,32H,4-6H2,1-3H3,(H2,20,29)(H,21,31)(H,22,25)(H,23,30)(H,26,27)/t7-,8+,10+,11+,13+,14+,15+,19+/m0/s1
InChI key:InChIKey=MEJOVVKHFORGKW-HOMBLFBHSA-N
SMILES:[C@H]([C@@H](NC(C)=O)C=O)(O[C@@H](C(N[C@H](C(N[C@H](CCC(O)=O)C(N)=O)=O)C)=O)C)[C@@H]([C@@H](CO)O)O
Synonyms:- (4R)-4-{[(2S)-2-{[(2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoyl]amino}propanoyl]amino}-5-amino-5-oxopentanoic acid (non-preferred name)
- (4R)-4-{[(2S)-2-{[(2R)-2-{[(2R,5S)-3-(acetylamino)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoyl]amino}propanoyl]amino}-5-amino-5-oxopentanoic acid (non-preferred name)
- 2: PN: WO2009039971 PAGE: 99 claimed protein
- <span class="text-smallcaps">D</smallcap>-α-Glutamine, N-(N-acetylmuramoyl)-<smallcap>L</span>-alanyl-
- <span class="text-smallcaps">D</smallcap>-α-Glutamine, N<sup>2</sup>-[N-(N-acetylmuramoyl)-<smallcap>L</span>-alanyl]-
- Acetylmuramoyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</span>-isoglutamine
- Acetylmuramyl-L-alanyl-D-isoglutamine
- Acetylmuramyl-alanyl-isoglutamine
- Brn 4220745
- D-alpha-Glutamine, N(sup 2)-(N-(N-acetylmuramoyl)-L-alanyl)-
- D-alpha-Glutamine, N2-(N-(N-acetylmuramoyl)-L-alanyl)-
- D-α-Glutamine, N-(N-acetylmuramoyl)-L-alanyl-
- D-α-Glutamine, N2-[N-(N-acetylmuramoyl)-L-alanyl]-
- MDP
- MDP-<span class="text-smallcaps">D</span>
- Muramoyl dipeptide
- Muramyl dipeptide
- N(sup 2)-(N-(N-Acetylmuramoyl)-L-alanyl)-D-alpha-glutamine
- N-(Acetylmuramoyl)-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</span>-isoglutamine
- N-(Acetylmuramoyl)alanyl-<span class="text-smallcaps">D</span>-isoglutamine
- N-(Acetylmuramoyl)alanyl-D-isoglutamine
- N-(N-Acetylmuramoyl)-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</span>-α-glutamine
- N-Acetylmuramoyl dipeptide
- N-Acetylmuramoyl-<span class="text-smallcaps">L</smallcap>-alanine-<smallcap>D</span>-isoGln
- N-Acetylmuramoylalanyl-<span class="text-smallcaps">D</span>-isoglutamine
- N-Acetylmuramyl dipeptide
- N-Acetylmuramyl-L-Alanyl-D-Isoglutamine
- N-Acetylmuramyl-L-alanine-D-isoGln
- N2-(N-(N-Acetylmuramoyl)-L-alanyl)-D-alpha-glutamine
- N2-[N-(N-Acetylmuramoyl)-L-alanyl]-D-α-glutamin
- N2-[N-(N-acetilmuramoil)-L-alanil]-D-α-glutamina
- N-(N-Acetylmuramoyl)-L-alanyl-D-α-glutamine
- N-(Acetylmuramoyl)-L-alanyl-D-isoglutamine
- N-Acetylmuramoylalanyl-D-isoglutamine
- AC-MURAMYL-ALA-D-ISOGLUTAMINE
- n-acetylmuramyl-l-alanyl-d-isoglutamine hydrate
- AC-MURAMYL-ALA-D-GLN
- ADJUVANT PEPTIDE
- N-ACETYL-MURAMYL-L-ALA-D-ISOGLN
- n(sup2)-(n-(n-acetylmuramoyl)-l-alanyl)-d-alpha-glutamin
- N-AC-MURAMYL-ALA-D-GLU-NH2
- AC-MURAMYL-ALA-D-ISOGLN-OH
- L-18-MDP
- n(sup2)-(n-(n-acetylmuramoyl)-l-alanyl)-d-alpha-glutamine
- N-Acetylmuramyl-L-alanyl-D-isoglnamine hydrate
- AC-MURAMYL-ALA-D-GLU-NH2
- Adjuvant Peptide, Muramyl dipeptide
- N-AC-MURAMYL-ALA-D-GLU-NH2 2H2O
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 8 products.
Ac-muramyl-Ala-D-Glu-NH₂
CAS:Muramyl dipeptide (MDP) inhibits HIV replication in CD4⁺ H9 lymphocytes..Formula:C19H32N4O11Purity:99.2%Color and Shape:White PowderMolecular weight:492.48PAF (Platelet-Activating Factor, bovine heart)
CAS:Formula:C19H32N4O11Purity:95%Color and Shape:In solution, ChloroformMolecular weight:492.48Muramyl dipeptide
CAS:MDP is a synthetic peptide promoting bone formation by modulating osteoclasts, osteoblasts, and Runx2 expression via MAPK pathways.Formula:C19H32N4O11Purity:99.34%Color and Shape:SolidMolecular weight:492.48N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate
CAS:Muramyl dipeptide is a component of the bacterial cell wall and is found in mycobacteria, mycoplasmas, spirochetes, and gram-positive bacteria. Muramyl dipeptide has been shown to induce the activation of macrophages and other cells by stimulating toll-like receptor 4. It also has significant cytotoxicity against various cancer cells, as well as potent inducers of ubiquitin ligases. The use of muramyl dipeptide in vitro was shown to inhibit replication of HIV-1 virus in human lymphocytes. This agent has also been used for the treatment of bowel disease.Formula:C19H32N4O11·xH2OPurity:Min. 96 Area-%Color and Shape:PowderMolecular weight:492.48 g/molAdjuvant Peptide
CAS:<p>Adjuvant Peptide is a glycol ether that has been shown to have biological properties. It is used in the production of Immunoassays and other biochemicals. Adjuvant Peptide is an experimental model for immunity, as it stimulates cellular responses and alters the immune system's response to antigens. It shows potential for use in treating bowel diseases, such as ulcerative colitis, because of its ability to stimulate macrophage activity and induce cytokine production.</p>Formula:C19H32N4O11•2H2OPurity:Min. 95%Molecular weight:528.51 g/molAdjuvant Peptide
CAS:<p>Adjuvant peptide is a research tool that can be used in the study of protein interactions, pharmacology and cell biology. It can also be used as an inhibitor for ion channels or receptors. Adjuvant peptide has a molecular weight of 638.2 Da and a purity of > 98%.</p>Formula:C19H32N4O11Purity:Min. 95%Molecular weight:492.48 g/mol
