CAS 53910-25-1: Pentostatin

Description:Pentostatin, with the CAS number 53910-25-1, is a purine nucleoside analog that exhibits potent antineoplastic properties. It is primarily used in the treatment of certain types of leukemia and lymphoma, particularly hairy cell leukemia. Pentostatin functions by inhibiting the enzyme adenosine deaminase, which is crucial for the metabolism of purines. This inhibition leads to the accumulation of toxic metabolites in lymphocytes, ultimately inducing apoptosis in malignant cells. The compound is typically administered intravenously and has a specific dosage regimen due to its potential side effects, which can include myelosuppression, gastrointestinal disturbances, and immunosuppression. Pentostatin is characterized by its molecular formula, which reflects its structure as a modified purine, and it is known for its relatively low solubility in water. Its therapeutic efficacy is often evaluated in clinical settings, and it is classified as an antimetabolite. As with any chemotherapeutic agent, careful monitoring of patients is essential to manage adverse effects and assess treatment response.

Formula:C₁₁H₁₆N₄O₄

InChI:InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1

InChI key:InChIKey=FPVKHBSQESCIEP-JQCXWYLXSA-N

SMILES:OCC1OC(N2C=NC3=C2NC=NCC3O)CC1O

Synonyms:
(8R)-3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
(8R)-3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
(8R)-3-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-7,8-dihydro-4H-imidazo[4,5-f][1,3]diazepin-8-ol
(R)-3-(2-Deoxy-Beta-D-Erythro-Pento-Furanosyl)-3,6,7,8-Tetrahydroimidazo[4,5-D
(R)-3-(2-Deoxy-Beta-D-Pentofuranosyl)-3,6,7,8-Tetrahydroimidazo(4,5-D)(1,3)D
(R)-Deoxycoformycin
(R)-Rahydro
2'-Dcf
2'-Dexoycoformycin
2’-Deoxycoformycin
See more synonyms
2’Dcf
Ci-825
Cl 67310465
Cl 825
Co-V
Co-Vidarabine
Coforin
Deaminase inhibitor
Deoxycoformycin
Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (8R)-
Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)-
Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (8R)-
Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)-
Nipent
Nsc 218321
Nsc 247520
Pd-Adi
Vira A deaminase inhibitor
(8R)-3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol

Found 8 products.

Product data	Purity	Price range	Estimated delivery
(8R)-3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol REF: IN-DA0038O6CAS: 53910-25-1	%	To inquire	Mon 14 Apr 25
Pentostatin REF: 7W-GP7108CAS: 53910-25-1	≥ 98.0% (anhydrous basis)	To inquire	Tue 15 Apr 25
Pentostatin REF: 54-BUP05961CAS: 53910-25-1	99.89%	284.00 €~758.00 €	Tue 15 Apr 25
Pentostatin REF: TM-T4006CAS: 53910-25-1	99.66% - 99.89%	44.00 €~509.00 €	Mon 21 Apr 25
Pentostatin REF: 54-BISN0008CAS: 53910-25-1	99%	56.00 €	Mon 21 Apr 25
Pentostatin REF: TR-P227350CAS: 53910-25-1	- - -	106.00 €~293.00 €	Tue 27 May 25
2'-Deoxycoformycin REF: 3D-AD03945CAS: 53910-25-1	Min. 95%	210.00 €~1,006.00 €	Tue 27 May 25
Pentostatin REF: 10-F386759CAS: 53910-25-1	97.0%	- - -	Discontinued product