CAS 53981-24-1

2-Amino-5-fluorophenol

Description:

2-Amino-5-fluorophenol is an organic compound characterized by the presence of an amino group (-NH2) and a fluorine atom attached to a phenolic ring. Its molecular formula is C6H6FNO, indicating it contains six carbon atoms, six hydrogen atoms, one nitrogen atom, and one fluorine atom. This compound typically appears as a solid at room temperature and is known for its potential applications in pharmaceuticals and as an intermediate in organic synthesis. The amino group contributes to its basicity, while the fluorine atom can influence its reactivity and solubility in various solvents. 2-Amino-5-fluorophenol may exhibit properties such as being a weak acid due to the phenolic hydroxyl group, and it can participate in various chemical reactions, including electrophilic aromatic substitution and nucleophilic reactions. Safety data indicates that, like many chemical substances, it should be handled with care, as it may pose health risks upon exposure. Proper safety measures, including the use of personal protective equipment, are recommended when working with this compound.

Formula: C₉H₈F₃NO₂

InChI: InChI=1/C9H8F3NO2/c10-9(11,12)7-3-1-6(5-13-7)2-4-8(14)15/h1,3,5H,2,4H2,(H,14,15)

InChI key: InChIKey=IIDUNAVOCYMUFB-UHFFFAOYSA-N

SMILES: c1cc(C(F)(F)F)ncc1CCC(=O)O

Synonyms:

• (4-Fluoro-2-hydroxyphenyl)amine
• 3-[6-(Trifluoromethyl)Pyridin-3-Yl]Propanoic Acid
• 4-Fluoro-2-hydroxyaniline
• 5-Fluoro-2-aminophenol
• Phenol, 2-amino-5-fluoro-

2-Amino-5-fluorophenol

CAS: 53981-24-1

Formula: C₆H₆FNO

Purity: 98%

Color and Shape: Solid

Molecular weight: 127.1163

Ref: IN-DA003GH2

2-Amino-5-Fluorophenol

CAS: 53981-24-1

2-AF: organic, in drug synthesis (anticancer, anti-inflammatory), and antimicrobial agents.

Formula: C₆H₆FNO

Purity: 99.41%

Color and Shape: Solid

Molecular weight: 127.12

Ref: TM-T1370

2-Amino-5-Fluorophenol

CAS: 53981-24-1

2-Amino-5-Fluorophenol

Purity: ≥98%

Molecular weight: 127.12g/mol

Ref: 54-BUP11266

2-Amino-5-fluorophenol

CAS: 53981-24-1

Formula: C₆H₆FNO

Purity: >97.0%(GC)

Color and Shape: White to Gray to Brown powder to crystal

Molecular weight: 127.12

Ref: 3B-A2300

2-Amino-5-fluorophenol

CAS: 53981-24-1

2-Amino-5-fluorophenol

Formula: C₆H₆FNO

Purity: 98%

Color and Shape: silvery brown/black crystalline powder

Molecular weight: 127.12g/mol

Ref: 54-PC9625

2-Amino-5-fluorophenol

CAS: 53981-24-1

2-Amino-5-fluorophenol (2AP) is a natural product that has been found to be an effective inhibitor of the enzyme fatty acid synthase. 2AP has been shown to inhibit the growth of Candida albicans, Trichophyton mentagrophytes, and Toxoplasma gondii in a model system. This compound is used as a starting material for the synthesis of other pharmaceutical compounds, such as fluoroquinolones and aminoglycosides. 2AP inhibits the activity of the enzyme fatty acid synthase by binding to the thiolate moiety on cysteine residues near the active site and thus preventing substrate binding. This inhibition results in a decrease in fatty acid synthesis, which leads to cell death.

Formula: C₆H₆FNO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 127.12 g/mol

Ref: 3D-FA44993

2-Amino-5-fluorophenol

CAS: 53981-24-1

Formula: C₆H₆FNO

Purity: 97%

Color and Shape: Solid

Molecular weight: 127.118

Ref: 10-F013054

2-Amino-5-fluorophenol

Controlled Product

CAS: 53981-24-1

Applications 2-Amino-5-fluorophenol is a fluoroaniline metabolite.
References Cnubben, N.H.P. et al.: Chem.-Biol. Inter., 85, 151 (1992); Rietjens, I.M.C.M. et al.: 19, 1297 (1989);

Formula: C₆H₆FNO

Color and Shape: Neat

Molecular weight: 127.12

Ref: TR-A609600