CAS 539823-80-8

Pneumocandin A0

Description:

Pneumocandin A0 is a lipopeptide compound that belongs to the class of echinocandins, which are known for their antifungal properties. It is produced by the fermentation of certain fungi, particularly species of Glarea lozoyensis. The compound exhibits a unique structure characterized by a cyclic hexapeptide core linked to a long fatty acid side chain, which contributes to its biological activity. Pneumocandin A0 primarily functions by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of fungal cell walls, thereby exerting its antifungal effects against various pathogenic fungi, including Candida species. Its mechanism of action makes it particularly effective in treating fungal infections, especially in immunocompromised patients. Additionally, Pneumocandin A0 has been studied for its potential use in combination therapies to enhance antifungal efficacy and reduce resistance. While it has shown promise in clinical settings, further research is ongoing to fully understand its pharmacokinetics, safety profile, and potential applications in antifungal therapy.

Formula: C₅₆H₇₁N₉O₁₉

InChI: InChI=1/C56H71N9O19/c1-4-5-6-19-83-34-17-13-29(14-18-34)40-22-35(63-84-40)28-7-9-31(10-8-28)49(75)58-36-21-39(70)52(78)62-54(80)45-46(72)26(2)24-65(45)56(82)43(38(69)23-41(57)71)60-53(79)44(48(74)47(73)30-11-15-32(67)16-12-30)61-51(77)37-20-33(68)25-64(37)55(81)42(27(3)66)59-50(36)76/h7-18,22,26-27,33,36-39,42-48,52,66-70,72-74,78H,4-6,19-21,23-25H2,1-3H3,(H2,57,71)(H,58,75)(H,59,76)(H,60,79)(H,61,77)(H,62,80)

InChI key: VJHYOZWFHJBKMZ-CICALKLBSA-N

SMILES: CCCCCOc1ccc(cc1)c1cc(c2ccc(cc2)C(=O)NC2CC(C(N=C(C3C(C(C)CN3C(=O)C(C(CC(=N)O)O)N=C(C(C(C(c3ccc(cc3)O)O)O)N=C(C3CC(CN3C(=O)C(C(C)O)N=C2O)O)O)O)O)O)O)O)no1

Synonyms:

• 1-[(4R,5R)-4,5-Dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-(3,4-dihydroxyphenyl)-4-hydroxy-L-threonine]-pneumocandin A0

Pneumocandin A0

CAS: 539823-80-8

Purity: 95%

Ref: IN-DA00DE97

Micafungin metabolite M1

CAS: 539823-80-8

Micafungin metabolite M1 is a micafungin metabolite with weak antifungal activity used in metabolism studies.

Formula: C₅₆H₇₁N₉O₂₀

Purity: 99.79%

Color and Shape: White Solid

Molecular weight: 1190.21

Ref: TM-TP3139

Micafungin Metabolite M1

CAS: 539823-80-8

Formula: C₅₆H₇₁N₉O₂₀

Color and Shape: White To Off-White Solid

Molecular weight: 1190.23

Ref: 4Z-PM-127005

Micafungin Metabolite M1

CAS: 539823-80-8

Micafungin Metabolite M1 is a metabolite of Micafungin. It is an impurity in the drug product and is not active. Micafungin Metabolite M1 has been proposed as a pharmacopoeia reference standard for HPLC quantification of Micafungin.

Formula: C₅₆H₇₁N₉O₂₀

Purity: Min. 95%

Molecular weight: 1,190.21 g/mol

Ref: 3D-IM183055

O-Desulfo Micafungin

CAS: 539823-80-8

Formula: C₅₆H₇₁N₉O₂₀

Molecular weight: 1190.2

Ref: ST-EA-CP-M94013