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CAS 54-47-7

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Pyridoxal 5′-phosphate

Description:
Pyridoxal 5′-phosphate (PLP) is the active form of vitamin B6 and plays a crucial role as a coenzyme in various enzymatic reactions, particularly those involving amino acids. It is a water-soluble compound characterized by its yellow crystalline appearance. PLP is involved in transamination, decarboxylation, and racemization reactions, facilitating the metabolism of amino acids and the synthesis of neurotransmitters. The molecule contains a pyridine ring, a hydroxymethyl group, and a phosphate group, which contribute to its biochemical activity. Its solubility in water allows it to easily participate in metabolic processes within the body. PLP is essential for the proper functioning of enzymes such as amino acid decarboxylases and transaminases, making it vital for protein metabolism and the production of neurotransmitters like serotonin and dopamine. Deficiency in pyridoxal 5′-phosphate can lead to various health issues, including anemia, neurological disorders, and impaired immune function. Overall, PLP is a key player in maintaining metabolic homeostasis and supporting overall health.
Formula:C8H10NO6P
InChI:InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChI key:InChIKey=NGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES:C(OP(=O)(O)O)C=1C(C=O)=C(O)C(C)=NC1
Synonyms:
  • (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate
  • 2-Methyl-3-hydroxy-4-formyl-5-pyridylmethylphosphoric acid
  • 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde
  • 3-Hydroxy-5-(Hydroxymethyl)-2-Methylpyridine-4-Carbaldehyde Phosphate (1:1)
  • 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate
  • 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-
  • 5'-Dihidrogenofosfato De Piridoxal
  • 5'-Dihydrogenophosphate de pyridoxal
  • Apolon B6
  • Apolon B<sub>6</sub>
  • See more synonyms
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