CAS 54063-53-5: Propafenone
Description:Propafenone is a class IC antiarrhythmic medication primarily used to treat certain types of irregular heartbeats, such as atrial fibrillation and ventricular tachycardia. It functions by blocking sodium channels, which helps to stabilize the cardiac cell membranes and restore normal heart rhythm. Propafenone is characterized by its chemical formula C21H27NO2, and it has a molecular weight of approximately 325.45 g/mol. The substance is typically administered orally and is available in various formulations, including extended-release tablets. Propafenone exhibits a moderate lipophilicity, which influences its absorption and distribution in the body. It is metabolized primarily in the liver, with a significant first-pass effect, leading to variable plasma concentrations among individuals. Side effects may include dizziness, gastrointestinal disturbances, and potential proarrhythmic effects, necessitating careful monitoring during treatment. Due to its pharmacological properties, Propafenone is classified as a prescription medication and should be used under medical supervision.
Formula:C21H27NO3
InChI:InChI=1S/C21H27NO3/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17/h3-11,18,22-23H,2,12-16H2,1H3
InChI key:InChIKey=JWHAUXFOSRPERK-UHFFFAOYSA-N
SMILES:O=C(C=1C=CC=CC1OCC(O)CNCCC)CCC=2C=CC=CC2
- Synonyms:
- (RS)-Propafenone
- 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-
- 1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone
- Gp 382
- Gpv 001
- Polfenon
- Propafenon
- Propafenona
- Sa 79
- (±)-Propafenone
- See more synonyms
- 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one
- Propafenone

Propafenone Hydrochloride
Ref: 3B-P2301
1g | 65.00 € |

Propafenone
Ref: TM-T0866
25mg | 47.00 € | ||
50mg | 70.00 € | ||
100mg | 103.00 € | ||
200mg | 153.00 € | ||
500mg | 249.00 € | ||
1mL*10mM (DMSO) | 47.00 € |

1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one
Ref: IN-DA019FSI
1g | 120.00 € | ||
5g | 292.00 € | ||
100mg | 47.00 € | ||
250mg | 59.00 € |

Propafenone
Controlled ProductRef: TR-P767403
1g | 155.00 € | ||
250mg | 102.00 € | ||
500mg | 129.00 € |

1-{2-[2-Hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one
Ref: 3D-ECA06353
250mg | Discontinued | Request information | |
2500mg | Discontinued | Request information |