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Propafenone

CAS 54063-53-5: Propafenone

Description:Propafenone is a class IC antiarrhythmic medication primarily used to treat certain types of irregular heartbeats, such as atrial fibrillation and ventricular tachycardia. It functions by blocking sodium channels, which helps to stabilize the cardiac cell membranes and restore normal heart rhythm. Propafenone is characterized by its chemical formula C21H27NO2, and it has a molecular weight of approximately 325.45 g/mol. The substance is typically administered orally and is available in various formulations, including extended-release tablets. Propafenone exhibits a moderate lipophilicity, which influences its absorption and distribution in the body. It is metabolized primarily in the liver, with a significant first-pass effect, leading to variable plasma concentrations among individuals. Side effects may include dizziness, gastrointestinal disturbances, and potential proarrhythmic effects, necessitating careful monitoring during treatment. Due to its pharmacological properties, Propafenone is classified as a prescription medication and should be used under medical supervision.

Formula:C21H27NO3

InChI:InChI=1S/C21H27NO3/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17/h3-11,18,22-23H,2,12-16H2,1H3

InChI key:InChIKey=JWHAUXFOSRPERK-UHFFFAOYSA-N

SMILES:O=C(C=1C=CC=CC1OCC(O)CNCCC)CCC=2C=CC=CC2

  • Synonyms:
  • (RS)-Propafenone
  • 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-
  • 1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone
  • Gp 382
  • Gpv 001
  • Polfenon
  • Propafenon
  • Propafenona
  • Sa 79
  • (±)-Propafenone
  • See more synonyms
  • 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one
  • Propafenone
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Found 5 products.

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Propafenone Hydrochloride

CAS:34183-22-7 54063-53-5

Ref: 3B-P2301

1g65.00 €
Estimated delivery in United States, on Monday 7 Apr 2025
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Propafenone

CAS:54063-53-5

Ref: TM-T0866

25mg47.00 €
50mg70.00 €
100mg103.00 €
200mg153.00 €
500mg249.00 €
1mL*10mM (DMSO)47.00 €
Estimated delivery in United States, on Monday 14 Apr 2025
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Ref: IN-DA019FSI

1g120.00 €
5g292.00 €
100mg47.00 €
250mg59.00 €
Estimated delivery in United States, on Monday 14 Apr 2025
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Propafenone

Controlled Product
CAS:54063-53-5

Ref: TR-P767403

1g155.00 €
250mg102.00 €
500mg129.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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1-{2-[2-Hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one

CAS:54063-53-5

Discontinued product
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