CAS 54063-53-5

Propafenone

Description:

Propafenone is a class IC antiarrhythmic medication primarily used to treat certain types of irregular heartbeats, such as atrial fibrillation and ventricular tachycardia. It functions by blocking sodium channels, which helps to stabilize the cardiac cell membranes and restore normal heart rhythm. Propafenone is characterized by its chemical formula C21H27NO2, and it has a molecular weight of approximately 325.45 g/mol. The substance is typically administered orally and is available in various formulations, including extended-release tablets. Propafenone exhibits a moderate lipophilicity, which influences its absorption and distribution in the body. It is metabolized primarily in the liver, with a significant first-pass effect, leading to variable plasma concentrations among individuals. Side effects may include dizziness, gastrointestinal disturbances, and potential proarrhythmic effects, necessitating careful monitoring during treatment. Due to its pharmacological properties, Propafenone is classified as a prescription medication and should be used under medical supervision.

Formula: C₂₁H₂₇NO₃

InChI: InChI=1S/C21H27NO3/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17/h3-11,18,22-23H,2,12-16H2,1H3

InChI key: InChIKey=JWHAUXFOSRPERK-UHFFFAOYSA-N

SMILES: O(CC(CNCCC)O)C1=C(C(CCC2=CC=CC=C2)=O)C=CC=C1

Synonyms:

• (RS)-Propafenone
• 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-
• 1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone
• Gp 382
• Gpv 001
• Polfenon
• Propafenon
• Propafenona
• Sa 79
• (±)-Propafenone
• 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one

Propafenone Hydrochloride

CAS: 34183-22-7, 54063-53-5

Formula: C₂₁H₂₇NO₃·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 377.91

Ref: 3B-P2301

Propafenone

CAS: 54063-53-5

Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.

Formula: C₂₁H₂₇NO₃

Purity: 99.02%

Color and Shape: Solid

Molecular weight: 341.44

Ref: TM-T0866

1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one

CAS: 54063-53-5

Formula: C₂₁H₂₇NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 341.4440

Ref: IN-DA019FSI

Propafenone

CAS: 54063-53-5

Propafenone

Purity: ≥98%

Molecular weight: 341.44g/mol

Ref: 54-BUP13988

Propafenone

Controlled Product

CAS: 54063-53-5

Applications Propafenone (cas# 54063-53-5) is a useful research chemical.

Formula: C₂₁H₂₇NO₃

Color and Shape: White To Off-White

Molecular weight: 341.444

Ref: TR-P767403