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Propafenone
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Propafenone

CAS: 54063-53-5

Ref. TM-T0866

25mg
46.00 €
50mg
69.00 €
100mg
101.00 €
200mg
153.00 €
500mg
244.00 €
1ml*10 (DMSO)
46.00 €
Estimated delivery in United States, on Friday 7 Jun 2024

Product Information

Name:
Propafenone
Synonyms:
  • Rythmol, Propafenonum
  • (RS)-Propafenone
  • 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-
  • 1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone
  • Gp 382
  • Gpv 001
  • Polfenon
  • Propafenon
  • Propafenona
  • Sa 79
  • See more synonyms
Description:

Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated. The electrophysiological effect of propafenone manifests itself in a reduction of upstroke velocity (Phase 0) of the monophasic action potential. In Purkinje fibers, and to a lesser extent myocardial fibers, propafenone reduces the fast inward current carried by sodium ions, which is responsible for the drugs antiarrhythmic actions. Diastolic excitability threshold is increased and effective refractory period prolonged. Propafenone reduces spontaneous automaticity and depresses triggered activity. At very high concentrations in vitro, propafenone can inhibit the slow inward current carried by calcium but this calcium antagonist effect probably does not contribute to antiarrhythmic efficacy.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
341.44
Formula:
C21H27NO3
Purity:
99.69%
Color/Form:
Solid
InChI:
InChI=1S/C21H27NO3/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17/h3-11,18,22-23H,2,12-16H2,1H3
InChI key:
InChIKey=JWHAUXFOSRPERK-UHFFFAOYSA-N
SMILES:
CCCNCC(O)COc1ccccc1C(=O)CCc1ccccc1
MDL:
Melting point:
Boiling point:
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Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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