CAS 5409-58-5

1-Propanone, 3-(dimethylamino)-1-(1-naphthalenyl)-, hydrochloride (1:1)

Description:

1-Propanone, 3-(dimethylamino)-1-(1-naphthalenyl)-, hydrochloride (1:1), commonly known as a derivative of naphthalene, is a chemical compound characterized by its structure that includes a propanone moiety and a dimethylamino group. This compound typically appears as a white to off-white crystalline solid and is soluble in water due to the presence of the hydrochloride salt form, which enhances its solubility compared to its free base. It exhibits properties typical of both ketones and amines, including potential reactivity in nucleophilic substitution reactions. The presence of the naphthalene ring contributes to its aromatic characteristics, which may influence its electronic properties and interactions with other molecules. This compound may be of interest in various fields, including medicinal chemistry and organic synthesis, due to its potential biological activity and utility as an intermediate in the synthesis of more complex organic compounds. As with many chemical substances, proper handling and safety precautions are essential, given its potential effects on health and the environment.

Formula: C₁₅H₁₇NO·ClH

InChI: InChI=1S/C15H17NO.ClH/c1-16(2)11-10-15(17)14-9-5-7-12-6-3-4-8-13(12)14;/h3-9H,10-11H2,1-2H3;1H

InChI key: InChIKey=GUTDWEKYWTXJGD-UHFFFAOYSA-N

SMILES: C(CCN(C)C)(=O)C=1C2=C(C=CC1)C=CC=C2.Cl

Synonyms:

• (3-Dimethylamino)-1''-Propionapthone Hydrochloride
• 1'-Propionaphthone,3-(dimethylamino)-, hydrochloride
• 1-Propanone,3-(dimethylamino)-1-(1-naphthalenyl)-, hydrochloride
• 3-Dimethylamino-1-(naphthalen-1-yl)propan-1-one hydrochloride
• 1-Propanone, 3-(dimethylamino)-1-(1-naphthalenyl)-, hydrochloride (1:1)

(3-DIMETHYLAMINO)-1''-PROPIONAPTHONE HYDROCHLORIDE

CAS: 5409-58-5

Formula: C₁₅H₁₈ClNO

Purity: 98%

Color and Shape: Solid

Molecular weight: 263.7625

Ref: IN-DA00DB7Y

3-(Dimethylamino)-1-(naphthalen-1-yl)propan-1-one hydrochloride

CAS: 5409-58-5

3-(Dimethylamino)-1-(naphthalen-1-yl)propan-1-one hydrochloride

Formula: C₁₅H₁₈ClNO

Purity: 98%

Molecular weight: 263.76

Ref: 54-OR80140

3-(Dimethylamino)-1-(naphthalen-1-yl)propan-1-one hydrochloride

CAS: 5409-58-5

Formula: C₁₅H₁₈ClNO

Purity: 98%

Color and Shape: Liquid, No data available.

Molecular weight: 263.77

Ref: 10-F377853

3-(Dimethylamino)-1-(1-naphthalenyl)-1-propanone Hydrochloride

Controlled Product

CAS: 5409-58-5

Applications 3-(Dimethylamino)-1-(1-naphthalenyl)-1-propanone Hydrochloride is a reactant used in the preparation of choline acetyltransferase (ChA) inhibitors.
References Sastry, B. et al.: Pharmacol. Res. Comm., 20, 751 (1988)

Formula: C₁₅H₁₈ClNO

Color and Shape: Neat

Molecular weight: 263.76

Ref: TR-D461195

3-(Dimethylamino)-1-(1-naphthalenyl)-1-propanone Hydrochloride-D6

Controlled Product

CAS: 5409-58-5

Applications 3-(Dimethylamino)-1-(1-naphthalenyl)-1-propanone Hydrochloride-D6 is a reagent in the synthesis of Bedaquiline-d6 (Mixture of Diastereomers) (B119552) which is the labelled analog of Bedaquiline, a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);

Formula: C₁₅H₁₁D₆NO•ClH

Color and Shape: Neat

Molecular weight: 269.8

Ref: TR-D461196

3-(Dimethylamino)-1-(naphthalen-1-yl)propan-1-one hydrochloride

CAS: 5409-58-5

3-(Dimethylamino)-1-(naphthalen-1-yl)propan-1-one hydrochloride

Formula: C₁₅H₁₈ClNO

Purity: 97%

Molecular weight: 263.76

Ref: IN-DG219695