CAS 54527-84-3
:Nicardipine hydrochloride
Description:
Nicardipine hydrochloride is a calcium channel blocker primarily used in the treatment of hypertension and angina pectoris. It functions by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. This compound is characterized by its chemical formula, which includes a dihydropyridine structure, contributing to its pharmacological activity. Nicardipine hydrochloride is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. The substance appears as a white to off-white crystalline powder and is soluble in water and alcohol. Its mechanism of action involves selective inhibition of L-type calcium channels, which helps to relax blood vessels and improve blood flow. Common side effects may include headache, flushing, and peripheral edema. As with any medication, it is essential to monitor for potential interactions with other drugs and to consider patient-specific factors when prescribing nicardipine hydrochloride.
Formula:C26H29N3O6·ClH
InChI:InChI=1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H
InChI key:InChIKey=AIKVCUNQWYTVTO-UHFFFAOYSA-N
SMILES:C(OCCN(CC1=CC=CC=C1)C)(=O)C=2C(C(C(OC)=O)=C(C)NC2C)C3=CC(N(=O)=O)=CC=C3.Cl
Synonyms:- 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-(N-benzyl-N-methylamino)]-ethyl ester 5-methyl ester hydrochloride
- 2-[Benzyl(Methyl)Amino]Ethyl Methyl 2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-Dicarboxylate Hydrochloride (1:1)
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-[2-[methyl(phenylmethyl)amino]ethyl] ester, hydrochloride (1:1)
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-[methyl(phenylmethyl)amino]ethyl ester, monohydrochloride
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Found 19 products.
Nicardipine Hydrochloride
CAS:Formula:C26H29N3O6·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Green powder to crystalMolecular weight:515.99Nicardipine hydrochloride, 98%
CAS:<p>L-type calcium channel blocker</p>Formula:C26H30ClN3O6Purity:98%Color and Shape:PowderMolecular weight:515.99NICARDIPINE FOR SYSTEM SUITABILITY CRS
CAS:<p>NICARDIPINE FOR SYSTEM SUITABILITY CRS</p>Formula:C26H29N3O6Molecular weight:479.525NICARDIPINE HYDROCHLORIDE CRS
CAS:<p>NICARDIPINE HYDROCHLORIDE CRS</p>Formula:C26H29N3O6Molecular weight:479.525Nicardipine Hydrochloride
CAS:<p>Compounds containing an unfused pyridine ring in the structure, nesoi</p>Formula:C26H29N3O6·HClColor and Shape:Pale Green Yellow Green PowderMolecular weight:479.20564Nicardipine hydrochloride
CAS:<p>Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.</p>Formula:C26H30ClN3O6Purity:99.58% - 99.89%Color and Shape:Yellow SolidMolecular weight:515.99Nicardipine hydrochloride
CAS:<p>Nicardipine hydrochloride</p>Purity:98%+Molecular weight:515.99g/molNicardipine hydrochloride
CAS:<p>Nicardipine hydrochloride</p>Purity:≥98%Molecular weight:515.99g/molNicardipine Hydrochloride
CAS:Controlled ProductFormula:C26H29N3O6·ClHColor and Shape:NeatMolecular weight:515.99Nicardipine Hydrochloride
CAS:<p>Applications Dihydropyridine calcium channel blocker. Antianginal; antihypertensive. Neuroprotective & Neuroresearch products.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Satoh, K., et al.: Clin. Exp. Pharmacol. Physiol., 7, 249 (1980), Sorkin, E.M., et al.: Drugs, 33, 296 (1987),<br></p>Formula:C26H29N3O6·ClHColor and Shape:YellowMolecular weight:515.99Nicardipine HCl - Bio-X ™
CAS:<p>Nicardipine is calcium channel blocker drug that is used for the treatment of hypertension and angina. This drug can also be used in the treatment of asthma and is said to enhance the action of various antineoplastic agents.</p>Formula:C26H29N3O6•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:515.99 g/molNicardipine hydrochloride
CAS:<p>L-type calcium channel blocker</p>Formula:C26H29N3O6•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:515.99 g/mol3-{2-[benzyl(methyl)amino]ethyl} 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
CAS:Formula:C26H30ClN3O6Purity:98.0%Molecular weight:515.99
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