CAS 5453-67-8

Dimethyl 2,6-pyridinedicarboxylate

Description:

Dimethyl 2,6-pyridinedicarboxylate, with the CAS number 5453-67-8, is an organic compound characterized by its pyridine ring structure substituted with two carboxylate groups at the 2 and 6 positions, each esterified with a methyl group. This compound typically appears as a colorless to pale yellow liquid or solid, depending on the temperature and purity. It is soluble in organic solvents such as ethanol and acetone but has limited solubility in water due to its hydrophobic nature. Dimethyl 2,6-pyridinedicarboxylate is often used as an intermediate in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. Its reactivity is influenced by the presence of the carboxylate groups, which can participate in various chemical reactions, including esterification and nucleophilic substitutions. Additionally, it may exhibit biological activity, making it of interest in medicinal chemistry. Proper handling and storage are essential, as with many organic compounds, to ensure safety and stability.

Formula: C₉H₉NO₄

InChI: InChI=1S/C9H9NO4/c1-13-8(11)6-4-3-5-7(10-6)9(12)14-2/h3-5H,1-2H3

InChI key: InChIKey=SNQQJEJPJMXYTR-UHFFFAOYSA-N

SMILES: C(OC)(=O)C=1N=C(C(OC)=O)C=CC1

Synonyms:

• 2,6-Bismethoxycarbonylpyridine
• 2,6-Dicarbomethoxypyridine
• 2,6-Dimethyl pyridine-2,6-dicarboxylate
• 2,6-Dipicolinic acid dimethyl ester
• 2,6-Pyridinedicarboxylic acid dimethyl ester
• 2,6-Pyridinedicarboxylic acid, 2,6-dimethyl ester
• Dimethyl pyridine-2,6-dicarboxylate
• Dipicolinic acid dimethyl ester
• NSC 18855
• Dimethyl 2,6-pyridinedicarboxylate

Dimethyl 2,6-Pyridinedicarboxylate

CAS: 5453-67-8

Formula: C₉H₉NO₄

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 195.17

Ref: 3B-P1444

Dimethyl pyridine-2,6-dicarboxylate, 98%

CAS: 5453-67-8

Eight macrocyclic bisamides and tetramides have been synthesized by reaction of dimethyl pyridine-2,6-dicarboxylate 1 with ,-diaminoethers in methanol as a solvent. Silver(I) coordination polymer and nine-coordinated cadmium(II) complex with dimethyl pyridine-2,6-dicarboxylate supported by solid sta

Formula: C₉H₉NO₄

Purity: 98%

Color and Shape: White to pale cream, Crystals or powder or crystalline powder

Molecular weight: 195.17

Ref: 02-H32251

Dimethyl pyridine-2,6-dicarboxylate

CAS: 5453-67-8

Formula: C₉H₉NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 195.1721

Ref: IN-DA0034QX

Dimethyl pyridine-2,6-dicarboxylate

CAS: 5453-67-8

Dimethyl pyridine-2,6-dicarboxylate

Formula: C₉H₉NO₄

Purity: 98%

Color and Shape: Solid-Crystals

Molecular weight: 195.17206

Ref: 54-OR914344

Dimethyl 2,6-pyridinedicarboxylate

CAS: 5453-67-8

Formula: C₉H₉NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 195.174

Ref: 10-F077285

2,6-Pyridinedicarboxylic acid dimethyl ester

CAS: 5453-67-8

2,6-Pyridinedicarboxylic acid dimethyl ester is a drug that has shown anticancer activity in animal models. It binds to DNA, forming a ternary complex with the DNA and the enzyme topoisomerase I. The binding of this drug to the enzyme prevents it from breaking the DNA strands during replication, causing the cell to die. It has been shown that 2,6-pyridinedicarboxylic acid dimethyl ester can be used as a non-competitive inhibitor of topoisomerase I. Furthermore, it has been demonstrated that 2,6-pyridinedicarboxylic acid dimethyl ester is able to bind to human endometrial cancer cells with high affinity. Finally, 2,6-pyridinedicarboxylic acid dimethyl ester was found in x-ray crystal structures of complexes with hydrogen bonds and low activation enthalpy and entropy.

Formula: C₉H₉NO₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 195.17 g/mol

Ref: 3D-FP44227

Dimethyl 2,6-Pyridinedicarboxylate

Controlled Product

CAS: 5453-67-8

Applications Dimethyl 2,6-Pyridinedicarboxylate (cas# 5453-67-8) is a compound useful in organic synthesis.

Formula: C₉H₉NO₄

Color and Shape: Neat

Molecular weight: 195.17

Ref: TR-D479060