CAS 54660-78-5

5-amino-4-chloropyrimidine

Description:

5-Amino-4-chloropyrimidine is an organic compound characterized by its pyrimidine ring structure, which is a six-membered aromatic ring containing two nitrogen atoms at positions 1 and 3. The presence of an amino group (-NH2) at position 5 and a chlorine atom (Cl) at position 4 contributes to its reactivity and potential applications in various chemical syntheses. This compound is typically a solid at room temperature and is soluble in polar solvents, which enhances its utility in organic reactions. It is often used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other nitrogen-containing compounds. The presence of both amino and halogen functional groups allows for further derivatization, making it a versatile building block in medicinal chemistry. Safety data indicates that, like many nitrogen-containing heterocycles, it should be handled with care, as it may pose health risks if ingested or inhaled. Overall, 5-amino-4-chloropyrimidine is a significant compound in the field of organic synthesis and medicinal chemistry.

Formula: C₄H₄ClN₃

InChI: InChI=1/C4H4ClN3/c5-4-3(6)1-7-2-8-4/h1-2H,6H2

SMILES: c1c(c(Cl)ncn1)N

Synonyms:

• 4-Chloropyrimidin-5-Amine
• 5-Pyrimidinamine, 4-Chloro-
• 4-Chloropyrimidin-5-Aminato
• 5-Amino-4-chloropyrimidine,96%
• 4-Chloro-5-pyrimidinamine
• 5-Pyrimidinamine, 4-chloro- (9CI)
• 4-Chloro-5-aMinopyriMidine
• Amino chloropyrimidine
• 5-AMINO-4-CHLOROPYRIMIDINE
• 4-chloro-pyriMidin-5-ylaMine

5-Amino-4-chloropyrimidine

CAS: 54660-78-5

Formula: C₄H₄ClN₃

Purity: >97.0%(GC)(T)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 129.55

Ref: 3B-A2937

5-Amino-4-chloropyrimidine, 96%

CAS: 54660-78-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₄ClN₃

Purity: 96%

Color and Shape: White to yellow to orange, Crystals or crystalline powder or powder

Molecular weight: 129.55

Ref: 02-H66671

5-Amino-4-Chloropyrimidine

CAS: 54660-78-5

Formula: C₄H₄ClN₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 129.5477

Ref: IN-DA00D8VH

5-Amino-4-chloropyrimidine

CAS: 54660-78-5

Purity: 95%

Molecular weight: 129.548

Ref: FT-A12682

5-Amino-4-chloropyrimidine

CAS: 54660-78-5

Purity: 95%

Molecular weight: 129.548

Ref: FT-CAPOA12682

5-Amino-4-chloropyrimidine

CAS: 54660-78-5

5-Amino-4-chloropyrimidine

Purity: 98%

Molecular weight: 129.55g/mol

Ref: 54-OR42122

5-Amino-4-chloropyrimidine

CAS: 54660-78-5

Formula: C₄H₄ClN₃

Purity: 95.0%

Color and Shape: Solid, Yellow powder

Molecular weight: 129.55

Ref: 10-F077408

4-Chloro-5-aminopyrimidine

CAS: 54660-78-5

4-Chloro-5-aminopyrimidine (4CAP) is an inhibitor of the enzyme purine nucleoside phosphorylase, which is involved in the synthesis of purines and pyrimidines. 4CAP has potent inhibitory activity with a Ki value of 0.06 μM, which is comparable to that of zebularine. 4CAP has also been shown to have antiinflammatory properties in lung tissue. The molecular modeling studies show that 4CAP binds to the hydroxyl group on the enzyme and prevents it from forming a covalent bond with its substrate. This causes a decrease in the rate of reaction time for the enzyme, resulting in decreased production of purines and pyrimidines.

Formula: C₄H₄ClN₃

Purity: Min. 95%

Molecular weight: 129.55 g/mol

Ref: 3D-NC57423