CAS 5467-71-0

Ethanone, 2-amino-1-(4-chlorophenyl)-, hydrochloride (1:1)

Description:

Ethanone, 2-amino-1-(4-chlorophenyl)-, hydrochloride (1:1), commonly referred to as a hydrochloride salt, is a chemical compound characterized by its amine and ketone functional groups. It features a 4-chlorophenyl group, which contributes to its potential biological activity and lipophilicity. The presence of the hydrochloride indicates that the compound is in its salt form, which often enhances solubility in water and stability compared to its free base form. This compound is typically used in pharmaceutical applications, particularly in the development of drugs due to its structural properties that may influence pharmacological effects. Its molecular structure allows for interactions with biological targets, making it of interest in medicinal chemistry. As with many amine-containing compounds, it may exhibit basicity and can participate in various chemical reactions, including acylation and alkylation. Safety and handling precautions are essential, as with all chemical substances, to mitigate any potential health risks associated with exposure.

Formula: C₈H₈ClNO·ClH

InChI: InChI=1S/C8H8ClNO.ClH/c9-7-3-1-6(2-4-7)8(11)5-10;/h1-4H,5,10H2;1H

InChI key: InChIKey=OVKMQHKVUWBLSV-UHFFFAOYSA-N

SMILES: C(CN)(=O)C1=CC=C(Cl)C=C1.Cl

Synonyms:

• 2-Amino-1-(4-chlorophenyl)-1-ethanone hydrochloride
• 2-Amino-1-(4-chlorophenyl)ethanone hydrochloride
• 2-Amino-4'-Chloroacetophenone Hydrochloride
• 2-Amino-4'-chloroacetophenone HCl
• 2-Amino-4'-chloroacetophenonehydrochloride
• Acetophenone,2-amino-4'-chloro-, hydrochloride
• Ethanone,2-amino-1-(4-chlorophenyl)-, hydrochloride
• a-Amino-4-chloroacetophenonehydrochloride
• a-Amino-p-chloroacetophenonehydrochloride
• p-Chlorophenacylamine hydrochloride
• α-Amino-4-chloroacetophenone hydrochloride
• α-Amino-p-chloroacetophenone hydrochloride

2-Amino-1-(4-chlorophenyl)ethanone, HCl

CAS: 5467-71-0

Formula: C₈H₉Cl₂NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 206.0692

Ref: IN-DA00DE49

4-Chlorophenacylamine hydrochloride

CAS: 5467-71-0

4-Chlorophenacylamine hydrochloride

Formula: C₈H₈ClNO·ClH

Purity: 95%

Molecular weight: 206.07g/mol

Ref: 54-OR9907

2-Amino-1-(4-chloro-phenyl)-ethanone; hydrochloride

CAS: 5467-71-0

Formula: C₈H₉Cl₂NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 206.07

Ref: 10-F030638

2-Amino-4'-chloroacetophenone hydrochloride

Controlled Product

CAS: 5467-71-0

2-Amino-4'-chloroacetophenone hydrochloride is a cytotoxic compound that inhibits the polymerization of tubulin. It has been shown to have cytotoxic effects and inhibit the growth of cancer cells in vitro at low micromolar concentrations. 2-Amino-4'-chloroacetophenone hydrochloride is a member of the cytotoxic class of compounds and can be used to slow or stop cell division by inhibiting the production of proteins vital for cell division, such as tubulin. This effect is due to its ability to bind to the beta subunit of tubulin, which disrupts its structure and prevents polymerization from occurring.

Formula: C₈H₈ClNO•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 206.07 g/mol

Ref: 3D-FA55395