CAS 54999-07-4

Ergolide

Description:

Ergolide, with the CAS number 54999-07-4, is a naturally occurring alkaloid derived from the ergot fungus, specifically from the Claviceps species. It is part of a larger class of compounds known as ergolines, which are characterized by their complex bicyclic structure. Ergolide exhibits a range of biological activities, including potential effects on the central nervous system, and has been studied for its interactions with various neurotransmitter receptors. The compound is typically found in a crystalline form and is soluble in organic solvents, but its solubility in water is limited. Due to its structural similarity to other ergoline derivatives, ergolide may share pharmacological properties with compounds like lysergic acid diethylamide (LSD) and other psychoactive substances. However, its specific applications and effects are less well-documented compared to more widely studied ergolines. As with many alkaloids, ergolide's use in research and potential therapeutic applications necessitate careful consideration of its pharmacodynamics and safety profile.

Formula: C₁₇H₂₂O₅

InChI: InChI=1S/C17H22O5/c1-8-7-12-14(9(2)16(20)22-12)15(21-10(3)18)17(4)11(8)5-6-13(17)19/h8,11-12,14-15H,2,5-7H2,1,3-4H3/t8-,11+,12+,14-,15+,17+/m1/s1

InChI key: InChIKey=JCDZXDWMCKMXFF-MMLVVLEOSA-N

SMILES: O(C(C)=O)[C@@H]1[C@@]2(C)[C@]([C@H](C)C[C@]3([C@]1(C(=C)C(=O)O3)[H])[H])(CCC2=O)[H]

Synonyms:

• Dihydrobigelovin
• Azuleno[6,5-b]furan-2,5-dione, 4-(acetyloxy)decahydro-4a,8-dimethyl-3-methylene-, (3aR,4S,4aR,7aS,8R,9aS)-
• Azuleno[6,5-b]furan-2,5-dione, 4-(acetyloxy)decahydro-4a,8-dimethyl-3-methylene-, [3aR-(3aα,4α,4aβ,7aα,8α,9aβ)]-
• Ergolide
• (3aR,4S,4aR,7aS,8R,9aS)-4-(Acetyloxy)decahydro-4a,8-dimethyl-3-methyleneazuleno[6,5-b]furan-2,5-dione

Ergolide

CAS: 54999-07-4

Ergolide, from Inula Britannica, inhibits iNOS and COX-2 by deactivating NF-κB in macrophages.

Formula: C₁₇H₂₂O₅

Purity: 99.64%

Color and Shape: Solid

Molecular weight: 306.35

Ref: TM-T13686

Ergolide

CAS: 54999-07-4

Formula: C₁₇H₂₂O₅

Purity: 99%

Molecular weight: 306.3536

Ref: IN-DA00DT4M

Ergolide

CAS: 54999-07-4

Formula: C₁₇H₂₂O₅

Molecular weight: 306.36

Ref: 7W-GY0348

Ergolide

CAS: 54999-07-4

Ergolide

Purity: ≥98%

Molecular weight: 306.35g/mol

Ref: 54-BUP04877

Ergolide

CAS: 54999-07-4

Formula: C₁₇H₂₂O₅

Purity: 95%~99%

Molecular weight: 306.358

Ref: BP-BP2078

Ergolide

CAS: 54999-07-4

Ergolide is a sesquiterpene lactone that has shown potent inhibitory activity against cancer cells. Ergolide inhibits the receptor activity of LPS-stimulated RAW 264.7 cells and has been shown to inhibit the growth factor production of TNFα. Ergolide also binds to DNA, which may be related to its ability to suppress tumor growth. It also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. Ergolide is used as an anti-cancer treatment, and has been shown to be effective in treating inflammatory diseases such as asthma and arthritis.

Formula: C₁₇H₂₂O₅

Purity: Min. 95%

Molecular weight: 306.4 g/mol

Ref: 3D-ECA99907