CAS 55-98-1: Busulfan

Description: Busulfan is a synthetic alkylating agent primarily used in chemotherapy for the treatment of certain types of cancers, particularly chronic myelogenous leukemia (CML) and as part of conditioning regimens prior to hematopoietic stem cell transplantation. It is characterized by its ability to form cross-links in DNA, which inhibits cell division and leads to cell death. Chemically, busulfan is a bis(2-chloroethyl) sulfone, and its structure includes a sulfonyl group that contributes to its reactivity. The compound is typically administered orally or intravenously and is known for its myelosuppressive effects, which can lead to a decrease in blood cell counts. Side effects may include nausea, vomiting, and potential long-term complications such as secondary malignancies or pulmonary toxicity. Due to its potent effects and specific therapeutic applications, busulfan is classified as a hazardous substance, requiring careful handling and monitoring during treatment. Its use is often guided by specific dosing protocols to maximize efficacy while minimizing adverse effects.

Formula: C₆H₁₄O₆S₂

InChI: InChI=1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3

InChI key: InChIKey=COVZYZSDYWQREU-UHFFFAOYSA-N

SMILES: O=S(=O)(OCCCCOS(=O)(=O)C)C

Synonyms:

• 1,4-Bis(methanesulfonoxy)butane
• 1,4-Bis(methanesulfonyloxy)butane
• 1,4-Butanediol dimesylate
• 1,4-Butanediol dimethanesulfonate
• 1,4-Butanediol, 1,4-dimethanesulfonate
• 1,4-Dibutanediol dimethanesulfonate
• 1,4-Dimethanesulfonoxybutane
• 1,4-Dimethylsulfonyloxybutane
• 2041Cb
• 4-Methylsulfonyloxybutyl methanesulfonate
• An 33501
• Busilvex
• Busulfano
• Busulfex
• Busulphan
• Butane-1,4-diyl bis(methanesulfonate)
• Butanediol dimethanesulphonate (mylran), 1,4-
• Cb 2041
• Citosulfan
• Glyzophrol
• Gt 2041
• Gt 41
• Leucosulfan
• Mablin
• Methanesulfonic acid, tetramethylene ester
• Mielevcin
• Mielosan
• Mielucin
• Milecitan
• Mileran
• Misulban
• Mitostan
• Myeloleukon
• Myelosan
• Mylecytan
• Myleran
• Myran
• Nci C01592
• Nsc 750
• Sulfabutin
• Sulphabutin
• Tetramethylene bis(methanesulfonate)
• X 149

1,4-Butanediol Dimethanesulfonate

CAS: 55-98-1

• Formula: C₆H₁₄O₆S₂
• Purity: >97.0%(T)
• Color and Shape: White to Light yellow to Light orange powder to crystaline
• Molecular weight: 246.29

Busulfan, 98%

CAS: 55-98-1

A cell cycle non-specific alkylating antineoplastic agent This Thermo Scientific Chemicals brand product was originally …

• Formula: C₆H₁₄O₆S₂
• Purity: 98%
• Molecular weight: 246.29

Busulfan CRS

CAS: 55-98-1

• Formula: C₆H₁₄O₆S₂
• Color and Shape: Powder
• Molecular weight: 246.3018

Busulfan

CAS: 55-98-1

• Formula: C₆H₁₄O₆S₂
• Purity: 100.0%
• Color and Shape: White Powder
• Molecular weight: 246.02318

1,4-Butanediol, dimethanesulfonate

CAS: 55-98-1

• Formula: C₆H₁₄O₆S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 246.3018

Busulfan

CAS: 55-98-1

Busulfan, a synthetic dimethane-sulfonate, has antineoplastic effects by alkylating DNA and hindering replication/transcription.

• Formula: C₆H₁₄O₆S₂
• Purity: 99.31% - 99.77%
• Color and Shape: White Needles Physical Description White Crystals Or Powder (Ntp 1992)
• Molecular weight: 246.3

Busulfan

CAS: 55-98-1

• Formula: C₆H₁₄O₆S₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 246.30

Busulfan

CAS: 55-98-1

• Formula: C₆H₁₄O₆S₂
• Purity: (Titration) 98.0 - 102.0 %
• Color and Shape: White to off-white powder
• Molecular weight: 246.29

Busulfan

CAS: 55-98-1

• Formula: C₆H₁₄O₆S₂
• Color and Shape: Neat
• Molecular weight: 246.30

Busulfan

CAS: 55-98-1

• Formula: C₆H₁₄O₆S₂
• Color and Shape: White Powder
• Molecular weight: 246.30

Busulfan

CAS: 55-98-1

Please enquire for more information about Busulfan including the price, delivery time and more detailed …

• Formula: C₆H₁₄O₆S₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 246.3 g/mol