CAS 55-98-1
:Busulfan
Description:
Busulfan is a synthetic alkylating agent primarily used in chemotherapy for the treatment of certain types of cancers, particularly chronic myelogenous leukemia (CML) and as part of conditioning regimens prior to hematopoietic stem cell transplantation. It is characterized by its ability to form cross-links in DNA, which inhibits cell division and leads to cell death. Chemically, busulfan is a bis(2-chloroethyl) sulfone, and its structure includes a sulfonyl group that contributes to its reactivity. The compound is typically administered orally or intravenously and is known for its myelosuppressive effects, which can lead to a decrease in blood cell counts. Side effects may include nausea, vomiting, and potential long-term complications such as secondary malignancies or pulmonary toxicity. Due to its potent effects and specific therapeutic applications, busulfan is classified as a hazardous substance, requiring careful handling and monitoring during treatment. Its use is often guided by specific dosing protocols to maximize efficacy while minimizing adverse effects.
Formula:C6H14O6S2
InChI:InChI=1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3
InChI key:InChIKey=COVZYZSDYWQREU-UHFFFAOYSA-N
SMILES:O(S(C)(=O)=O)CCCCOS(C)(=O)=O
Synonyms:- 1,4-Bis(methanesulfonoxy)butane
- 1,4-Bis(methanesulfonyloxy)butane
- 1,4-Butanediol dimesylate
- 1,4-Butanediol dimethanesulfonate
- 1,4-Butanediol, 1,4-dimethanesulfonate
- 1,4-Dibutanediol dimethanesulfonate
- 1,4-Dimethanesulfonoxybutane
- 1,4-Dimethylsulfonyloxybutane
- 2041Cb
- 4-Methylsulfonyloxybutyl methanesulfonate
- An 33501
- Busilvex
- Busulfano
- Busulfex
- Busulphan
- Butane-1,4-diyl bis(methanesulfonate)
- Butanediol dimethanesulphonate (mylran), 1,4-
- Cb 2041
- Citosulfan
- Glyzophrol
- Gt 2041
- Gt 41
- Leucosulfan
- Mablin
- Methanesulfonic acid, tetramethylene ester
- Mielevcin
- Mielosan
- Mielucin
- Milecitan
- Mileran
- Misulban
- Mitostan
- Myeloleukon
- Myelosan
- Mylecytan
- Myleran
- Myran
- Nci C01592
- Nsc 750
- Sulfabutin
- Sulphabutin
- Tetramethylene bis(methanesulfonate)
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 12 products.
1,4-Butanediol Dimethanesulfonate
CAS:Formula:C6H14O6S2Purity:>97.0%(T)Color and Shape:White to Light yellow to Light orange powder to crystalineMolecular weight:246.29Busulfan, 98%
CAS:<p>A cell cycle non-specific alkylating antineoplastic agent</p>Formula:C6H14O6S2Purity:98%Molecular weight:246.29Busulfan
CAS:BusulfanFormula:C6H14O6S2Purity:100.0%Color and Shape:White PowderMolecular weight:246.02318Busulfan
CAS:Acyclic dihydric alcohols, nesoiFormula:C6H14O6S2Color and Shape:White Off-White Crystalline PowderMolecular weight:246.023181,4-Butanediol, dimethanesulfonate
CAS:Formula:C6H14O6S2Purity:98%Color and Shape:SolidMolecular weight:246.3018Busulfan
CAS:Busulfan, a synthetic dimethane-sulfonate, has antineoplastic effects by alkylating DNA and hindering replication/transcription.Formula:C6H14O6S2Purity:99.31% - 99.89%Color and Shape:White Needles Physical Description White Crystals Or Powder (Ntp 1992)Molecular weight:246.3Busulfan
CAS:Formula:C6H14O6S2Purity:(Titration) 98.0 - 102.0 %Color and Shape:White to off-white powderMolecular weight:246.29Busulfan
CAS:<p>Busulfan is a chemotherapy drug that is used to treat certain cancers and blood disorders. Busulfan is administered intravenously as an injection solution, which may be given over 1 to 4 hours depending on the dose. Busulfan has a concentration-time curve with a rapid onset of action and short duration of action. The elimination half-life is about 2 hours. Busulfan has been shown to have immunosuppressive effects in experimental models of autoimmune diseases and hyperproliferative diseases such as lymphomas and myelogenous leukemia. The mechanism of this effect is not known, but it may be due to inhibition of IL-2 receptor binding or inhibition of the polymerase chain reaction (PCR).</p>Formula:C6H14O6S2Purity:Min. 95%Color and Shape:PowderMolecular weight:246.3 g/mol
