CAS 550-99-2

Naphazoline hydrochloride

Description:

Naphazoline hydrochloride is a sympathomimetic agent primarily used as a topical decongestant in nasal and ophthalmic formulations. It is a white to off-white crystalline powder that is soluble in water and alcohol, making it suitable for various pharmaceutical applications. The compound acts by stimulating alpha-adrenergic receptors, leading to vasoconstriction and reduced swelling in mucous membranes. This mechanism makes it effective in relieving nasal congestion and eye redness. Naphazoline hydrochloride is typically administered in low concentrations due to its potency and potential side effects, which can include local irritation, rebound congestion, and systemic effects if absorbed in significant amounts. It is important to use this medication as directed to minimize risks. Additionally, it is classified as a prescription medication in some regions, highlighting the need for professional guidance in its use. Overall, naphazoline hydrochloride is a valuable compound in the treatment of nasal and ocular conditions, but caution is advised regarding its application and dosage.

Formula: C₁₄H₁₄N₂·ClH

InChI: InChI=1S/C14H14N2.ClH/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14;/h1-7H,8-10H2,(H,15,16);1H

InChI key: InChIKey=DJDFFEBSKJCGHC-UHFFFAOYSA-N

SMILES: C(C=1C2=C(C=CC1)C=CC=C2)C=3NCCN3.Cl

Synonyms:

• 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, hydrochloride (1:1)
• 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, monohydrochloride
• 2-(1-Naphthylmethyl)imidazoline hydrochloride
• 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazol-3-ium
• 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole hydrochloride (1:1)
• 2-(α-Naphthylmethyl)-2-imidazoline hydrochloride
• 2-Imidazoline, 2-(1-naphthylmethyl)-, monohydrochloride
• Ak-Con
• Albalon
• Allerest Eye Drops
• Clera
• Coldan
• Comfort Eye Drops
• Degest 2
• Iridina Due
• Naphazoline HCl
• Naphazoline chloride
• Naphazoline hydrochloride
• Naphcon
• Naphthasolium chloride
• Naphthasoliumchloride
• Naprisol
• Neozoline
• Niazol
• Ocumethyl
• Opcon
• Privine (American)
• Privine hydrochloride
• Privinehydrochloride
• Prizole hydrochloride
• Prizolehydrochloride
• Rhinantin
• Rhinatin
• Rhinoperd
• Sanorin-Spofa
• Strictylon
• Stricylon
• Vasoclear
• Vasocon

Naphazoline Hydrochloride

CAS: 550-99-2

Formula: C₁₄H₁₄N₂·HCl

Purity: >99.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 246.74

Ref: 3B-N0542

2-(1-Naphthylmethyl)-2-imidazoline hydrochloride, 99%

CAS: 550-99-2

Naphazoline hydrochloride produces ionotropic effects via -adrenoceptor stimulation. It is an activator of AR and Nischarin. It is used as a nasal decongestant and ocular vasoconstrictor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some doc

Formula: C₁₄H₁₅ClN₂

Purity: 99%

Color and Shape: White to pale cream, Crystals or powder or crystalline powder

Molecular weight: 246.74

Ref: 02-B24161

Naphazoline Hydrochloride

CAS: 550-99-2

Color and Shape: Neat

Ref: 61-FOR0075.00

NAPHAZOLINE HYDROCHLORIDE CRS

CAS: 550-99-2

NAPHAZOLINE HYDROCHLORIDE CRS

Formula: C₁₄H₁₅ClN₂

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 246.7353

Ref: 41-N0080000

Naphazoline Hydrochloride

CAS: 550-99-2

Compounds containing an unfused imidazole ring (whether

Formula: C₁₄H₁₄N₂·ClH

Color and Shape: White Crystalline Powder

Molecular weight: 246.74

Ref: 45-1457006

Naphazoline hydrochloride

CAS: 550-99-2

Formula: C₁₄H₁₅ClN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 246.7353

Ref: IN-DA00DDW1

Naphazoline hydrochloride

CAS: 550-99-2

Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.

Formula: C₁₄H₁₅ClN₂

Purity: 97.93%

Color and Shape: White Crystalline Powder White Crystalline Powder

Molecular weight: 246.74

Ref: TM-T0446

Naphazoline HCl

CAS: 550-99-2

Formula: C₁₄H₁₄N₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 210.28 36.46

Ref: 4Z-N-3312

Naphazoline hydrochloride

CAS: 550-99-2

Naphazoline hydrochloride

Purity: ≥95%

Molecular weight: 246.74g/mol

Ref: 54-BUP19613

Naphazoline-d4 HCl

CAS: 550-99-2

Formula: C₁₄H₁₀D₄N₂·HCl

Color and Shape: Off-White Solid

Molecular weight: 214.31 36.46

Ref: 4Z-N-332

Naphazoline hydrochloride

CAS: 550-99-2

Formula: C₁₄H₁₄N₂HCl

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 246.74

Ref: 7W-GP3787

Naphazoline Hydrochloride

CAS: 550-99-2

Color and Shape: Neat

Ref: 86-MM0075.00

Naphazoline Hydrochloride

Controlled Product

CAS: 550-99-2

Stability Hygroscopic
Applications Naphazoline Hydrochloride is a useful synthetic intermediate used in eye drops. A vasoconstrictor.
References Zhang, S., et al.: Shipin Yu Yaopin, 13, 42 (2011); Markov, I.A., et al. Eye drops, which have anti-infectious, anti-inflammatory and anti-allergic action. RU 2493823 C1 20130927. Sep 27, 2013;

Formula: C₁₄H₁₄N₂·ClH

Color and Shape: Neat

Molecular weight: 246.74

Ref: TR-N343950

4,5-Dihydro-2-(1-naphthylmethyl)-1H-imidazole hydrochloride

CAS: 550-99-2

4,5-Dihydro-2-(1-naphthylmethyl)-1H-imidazole hydrochloride is a fatty acid that functions as an adrenergic receptor agonist. It has been shown to be effective in the diagnosis of cutaneous squamous cell carcinoma. 4,5-Dihydro-2-(1-naphthylmethyl)-1H-imidazole hydrochloride has also shown to have anti-cancer effects in animal models of cancer. This drug binds to fatty acid esters and can be used as a crosslinking agent for polymers. 4,5-Dihydro-2-(1-naphthylmethyl)-1H-imidazole hydrochloride is available as a sodium citrate solution for injection.

Formula: C₁₄H₁₄N₂·HCl

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 246.74 g/mol

Ref: 3D-FD11448