CAS 550-99-2
:Naphazoline hydrochloride
Description:
Naphazoline hydrochloride is a sympathomimetic agent primarily used as a topical decongestant in nasal and ophthalmic formulations. It is a white to off-white crystalline powder that is soluble in water and alcohol, making it suitable for various pharmaceutical applications. The compound acts by stimulating alpha-adrenergic receptors, leading to vasoconstriction and reduced swelling in mucous membranes. This mechanism makes it effective in relieving nasal congestion and eye redness. Naphazoline hydrochloride is typically administered in low concentrations due to its potency and potential side effects, which can include local irritation, rebound congestion, and systemic effects if absorbed in significant amounts. It is important to use this medication as directed to minimize risks. Additionally, it is classified as a prescription medication in some regions, highlighting the need for professional guidance in its use. Overall, naphazoline hydrochloride is a valuable compound in the treatment of nasal and ocular conditions, but caution is advised regarding its application and dosage.
Formula:C14H14N2·ClH
InChI:InChI=1S/C14H14N2.ClH/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14;/h1-7H,8-10H2,(H,15,16);1H
InChI key:InChIKey=DJDFFEBSKJCGHC-UHFFFAOYSA-N
SMILES:C(C=1C2=C(C=CC1)C=CC=C2)C=3NCCN3.Cl
Synonyms:- 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, hydrochloride (1:1)
- 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, monohydrochloride
- 2-(1-Naphthylmethyl)imidazoline hydrochloride
- 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazol-3-ium
- 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole hydrochloride (1:1)
- 2-(α-Naphthylmethyl)-2-imidazoline hydrochloride
- 2-Imidazoline, 2-(1-naphthylmethyl)-, monohydrochloride
- Ak-Con
- Albalon
- Allerest Eye Drops
- Clera
- Coldan
- Comfort Eye Drops
- Degest 2
- Iridina Due
- Naphazoline HCl
- Naphazoline chloride
- Naphazoline hydrochloride
- Naphcon
- Naphthasolium chloride
- Naphthasoliumchloride
- Naprisol
- Neozoline
- Niazol
- Ocumethyl
- Opcon
- Privine (American)
- Privine hydrochloride
- Privinehydrochloride
- Prizole hydrochloride
- Prizolehydrochloride
- Rhinantin
- Rhinatin
- Rhinoperd
- Sanorin-Spofa
- Strictylon
- Stricylon
- Vasoclear
- Vasocon
- See more synonyms
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Naphazoline Hydrochloride
CAS:Formula:C14H14N2·HClPurity:>99.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:246.742-(1-Naphthylmethyl)-2-imidazoline hydrochloride, 99%
CAS:Naphazoline hydrochloride produces ionotropic effects via -adrenoceptor stimulation. It is an activator of AR and Nischarin. It is used as a nasal decongestant and ocular vasoconstrictor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some docFormula:C14H15ClN2Purity:99%Color and Shape:White to pale cream, Crystals or powder or crystalline powderMolecular weight:246.74NAPHAZOLINE HYDROCHLORIDE CRS
CAS:NAPHAZOLINE HYDROCHLORIDE CRSFormula:C14H15ClN2Color and Shape:Crystalline Powder. White. Powder.Molecular weight:246.7353Naphazoline Hydrochloride
CAS:Compounds containing an unfused imidazole ring, whether or not hydrogenated, in the structure, nesoiFormula:C14H14N2·ClHColor and Shape:White Crystalline PowderMolecular weight:246.74Naphazoline hydrochloride
CAS:Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.Formula:C14H15ClN2Purity:97.93%Color and Shape:White SolidMolecular weight:246.735Naphazoline-d4 HCl
CAS:Formula:C14H10D4N2·HClColor and Shape:Off-White SolidMolecular weight:214.30 36.46Naphazoline HCl
CAS:Formula:C14H14N2·HClColor and Shape:White To Off-White SolidMolecular weight:210.28 36.46Naphazoline hydrochloride
CAS:Formula:C14H14N2HClPurity:(HPLC) ≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:246.74Naphazoline hydrochloride (Standard)
CAS:Naphazoline hydrochloride (Standard) is the standard substance of Naphazoline hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.Formula:C14H15ClN2Molecular weight:246.7351H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, hydrochloride (1:1)
CAS:Formula:C14H15ClN2Purity:99%Color and Shape:SolidMolecular weight:246.7353Naphazoline Hydrochloride
CAS:Formula:C14H14N2·ClHColor and Shape:White To Off-WhiteMolecular weight:246.74Naphazoline Hydrochloride
CAS:Controlled ProductStability Hygroscopic
Applications Naphazoline Hydrochloride is a useful synthetic intermediate used in eye drops. A vasoconstrictor.
References Zhang, S., et al.: Shipin Yu Yaopin, 13, 42 (2011); Markov, I.A., et al. Eye drops, which have anti-infectious, anti-inflammatory and anti-allergic action. RU 2493823 C1 20130927. Sep 27, 2013;Formula:C14H14N2·ClHColor and Shape:NeatMolecular weight:246.744,5-Dihydro-2-(1-naphthylmethyl)-1H-imidazole hydrochloride
CAS:4,5-Dihydro-2-(1-naphthylmethyl)-1H-imidazole hydrochloride is a fatty acid that functions as an adrenergic receptor agonist. It has been shown to be effective in the diagnosis of cutaneous squamous cell carcinoma. 4,5-Dihydro-2-(1-naphthylmethyl)-1H-imidazole hydrochloride has also shown to have anti-cancer effects in animal models of cancer. This drug binds to fatty acid esters and can be used as a crosslinking agent for polymers. 4,5-Dihydro-2-(1-naphthylmethyl)-1H-imidazole hydrochloride is available as a sodium citrate solution for injection.Formula:C14H14N2·HClPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:246.74 g/mol
