CAS 552-16-9

2-Nitrobenzoic acid

Description:

2-Nitrobenzoic acid is an aromatic carboxylic acid characterized by the presence of a nitro group (-NO2) and a carboxylic acid group (-COOH) attached to a benzene ring. Its molecular formula is C7H5NO4, and it features a nitro group positioned at the ortho position relative to the carboxylic acid group. This compound typically appears as a yellow crystalline solid and is known for its moderate solubility in water, with better solubility in organic solvents such as ethanol and acetone. 2-Nitrobenzoic acid is utilized in various chemical syntheses, including the preparation of dyes, pharmaceuticals, and other organic compounds. It exhibits acidic properties, allowing it to participate in acid-base reactions. Additionally, it can undergo electrophilic substitution reactions due to the electron-withdrawing nature of the nitro group, influencing the reactivity of the aromatic ring. Safety precautions should be taken when handling this compound, as it may pose health risks if ingested or inhaled.

Formula: C₇H₅NO₄

InChI: InChI=1S/C7H5NO4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)

InChI key: InChIKey=SLAMLWHELXOEJZ-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(N(=O)=O)C=CC=C1

Synonyms:

• 2-Nitrobenzoesaure
• 2-Nitrobenzoic Acid
• Acide 2-nitrobenzoique
• Acido 2-Nitrobenzoico
• Benzoic acid, o-nitro-
• Nsc 9576
• o-Carboxynitrobenzene
• o-Nitrobenzoic acid
• Benzoic acid, 2-nitro-

2-Nitrobenzoic acid, 95%

CAS: 552-16-9

It is employed as a synthetic reagent and can function as a growth supplement for Pseudomonas fluorescens strain KU-7. It also finds its use as a reagent for protection of amine groups and in organic synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar prod

Formula: C₇H₅NO₄

Purity: 95%

Color and Shape: White to cream or pale yellow, Crystals or powder or crystalline powder

Molecular weight: 167.12

Ref: 02-A10393

2-Nitrobenzoic Acid

CAS: 552-16-9

Formula: C₇H₅NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 167.1189

Ref: IN-DA003HSG

2-Nitrobenzoic acid

CAS: 552-16-9

2-Nitrobenzoic acid

Formula: C₇H₅NO₄

Purity: 99%

Molecular weight: 167.12

Ref: 54-OR79866

2-Nitrobenzoic acid

CAS: 552-16-9

2-Nitrobenzoic acid

Formula: C₇H₅NO₄

Purity: ≥98%

Molecular weight: 167.12

Ref: 54-BUP18320

2-Nitrobenzoic acid

CAS: 552-16-9

2-Nitrobenzoic acid is an anti-growth agent with an IC50 of 8.3 μM against Jurkat cells with T-type Ca²⁺ channel alpha 1H/delta 25.

Formula: C₇H₅NO₄

Purity: 99.97%

Color and Shape: Solid

Molecular weight: 167.12

Ref: TM-T64387

2-Nitrobenzoic-d4 Acid

CAS: 552-16-9, 855997-63-6

Formula: O₂NC₆D₄COOH

Purity: 98 atom % D

Color and Shape: Pale Yellow Solid

Molecular weight: 171.04696

Ref: 3U-D7316

2-Nitrobenzoic Acid

CAS: 552-16-9

Formula: C₇H₅NO₄

Purity: >95.0%(GC)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 167.12

Ref: 3B-N0155

2-Nitrobenzoic acid

CAS: 552-16-9

Formula: C₇H₅NO₄

Color and Shape: Neat

Molecular weight: 167.12

Ref: 04-C15557400

2-Nitrobenzoic acid

CAS: 552-16-9

2-Nitrobenzoic acid

Formula: C₇H₅NO₄

Purity: 98%

Molecular weight: 167.12

Ref: IN-DG77693

2-Nitrobenzoic acid - Technical

CAS: 552-16-9

2-Nitrobenzoic acid is an organic compound that is used as a reagent in the preparation of aldehydes, esters, and amides. It has been shown to be a potent inhibitor of the MCL-1 protein. This protein is an important regulator of mitochondrial permeability transition pore (MPTP) opening and apoptosis induction. The inhibition of the MPTP by 2-nitrobenzoic acid may be due to its ability to react with nitric oxide (NO) to form peroxynitrite, which reacts with MPTP proteins in the mitochondria. The use of 2-nitrobenzoic acid has been found to be effective in treating infectious diseases such as HIV, as well as autoimmune diseases such as psoriasis.

Formula: C₇H₅NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 167.12 g/mol

Ref: 3D-FN172456

2-Nitrobenzoic acid

CAS: 552-16-9

2-Nitrobenzoic acid is a diagnostic chemical that has been used for the detection of epidermal growth factor. It also has therapeutic properties, and has been used to treat infectious diseases and autoimmune diseases. 2-Nitrobenzoic acid is an organic compound that contains two nitro groups, which are connected to a benzene ring by two carbon chains. The molecule also contains two aldehyde groups, which are connected to the benzene ring by one carbon chain each. 2-Nitrobenzoic acid is a white crystalline solid with a melting point of 118°C and boiling point of 310°C. It is soluble in water and alcohols, but insoluble in ethers or chloroform.
2-Nitrobenzoic acid can be synthesized from nitric acid and benzoic acid. This reaction produces enough heat to ignite the mixture if it's not cooled down first.

Formula: C₇H₅NO₄

Purity: Min. 94 Area-%

Color and Shape: Powder

Molecular weight: 167.12 g/mol

Ref: 3D-FN38281

o-Nitrobenzoic acid pure, 95%

CAS: 552-16-9

Formula: C₇H₅NO₄

Purity: min. 95%

Color and Shape: White to Yellow to Faint beige to Faint brown, Powder, Clear, Colourless to Yellow to Faint beige to Faint brown

Molecular weight: 167.12

Ref: SR-16148

2-Nitrobenzoic acid

CAS: 552-16-9

Formula: C₇H₅NO₄

Purity: 95%

Color and Shape: Solid, Crystalline

Molecular weight: 167.12

Ref: 10-F079133

2-Nitrobenzoic Acid

Controlled Product

CAS: 552-16-9

Applications 2-Nitrobenzoic Acid is used as a reagent in the synthesis of several organic compounds including that of novel triazoles and a tetrazole of escitalopram which act as cholinesterase inhibitors. It is also used in the one pot synthesis of 1,4-disubstituted 1,2,3-triazoles.
References Mehr, N., et al.: Bioorg. Med. Chem., 23, 6014 (2015); Zhao, F., et al.: Chinese Chem. Lett., 27, 109 (2016);

Formula: C₇H₅NO₄

Color and Shape: Neat

Molecular weight: 167.12

Ref: TR-N493515