CymitQuimica logo

CAS 5534-13-4

:

Betamethasone 17-propionate

Description:
Betamethasone 17-propionate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is primarily used in dermatological formulations to treat various skin conditions, including eczema and psoriasis. The substance is characterized by its high potency and effectiveness in reducing inflammation and suppressing immune responses. Betamethasone 17-propionate is a white to off-white crystalline powder that is practically insoluble in water but soluble in organic solvents like ethanol and acetone. Its chemical structure includes a steroid backbone with a propionate ester at the 17-position, which enhances its skin penetration and therapeutic efficacy. The compound is typically administered topically, and its use is associated with a lower risk of systemic side effects compared to other corticosteroids due to its localized action. However, prolonged use can lead to skin atrophy and other local adverse effects. As with all corticosteroids, it is important to use Betamethasone 17-propionate under medical supervision to mitigate potential risks and ensure appropriate therapeutic outcomes.
Formula:C25H33FO6
InChI:InChI=1S/C25H33FO6/c1-5-21(31)32-25(20(30)13-27)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,26)19(29)12-23(18,25)4/h8-9,11,14,17-19,27,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1
InChI key:InChIKey=ITYMTTQVNYAJAA-XGQKBEPLSA-N
SMILES:O(C(CC)=O)[C@@]1(C(CO)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]
Synonyms:
  • (11Beta,16Beta)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Propanoate
  • (11β,16β)-9-Fluoro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
  • 226-887-6
  • Betamethasone 17-propionate
  • Betamethasone 17α-propionate
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)-, (11β,16β)-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 17-propionate
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 10 products.