CAS 554-57-4: Methazolamide

Description: Methazolamide is a carbonic anhydrase inhibitor primarily used in the treatment of glaucoma and certain types of edema. It is a sulfonamide derivative, characterized by its ability to reduce intraocular pressure by decreasing the production of aqueous humor in the eye. The chemical formula of methazolamide is C4H6N4O3S, and it features a sulfonamide group, which is essential for its pharmacological activity. Methazolamide is typically administered orally and is known for its relatively rapid onset of action. Its solubility in water is moderate, which influences its bioavailability. Common side effects may include metabolic acidosis, electrolyte imbalances, and gastrointestinal disturbances. Due to its mechanism of action, methazolamide can also lead to increased urinary excretion of bicarbonate, which may result in a decrease in blood pH. As with any medication, it is important for patients to consult healthcare professionals for appropriate dosing and potential interactions with other drugs.

Formula: C₅H₈N₄O₃S₂

InChI: InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)

InChI key: InChIKey=FLOSMHQXBMRNHR-UHFFFAOYSA-N

SMILES: O=C(N=C1SC(=NN1C)S(=O)(=O)N)C

Synonyms:

• 5-Acetylimino-4-methyl-Δ2-1,3,4-thiadiazoline-2-sulfonamide
• 5-Acetylimino-4-methyl-Δ²-1,3,4-thiadiazoline-2-sulfonamide
• Acetamide, N-(4-methyl-2-sulfamoyl-Δ2-1,3,4-thiadiazolin-5-ylidene)-
• Acetamide, N-(4-methyl-2-sulfamoyl-Δ²-1,3,4-thiadiazolin-5-ylidene)-
• L 584601
• Metazolamida
• Metazolamide
• Methazolamid
• Methazolamide
• Methenamide
• N-(4-Methyl-2-sulfamoyl-Δ2-1,3,4-thiadiazolin-5-ylidene)acetamide
• N-(4-Methyl-2-sulfamoyl-Δ²-1,3,4-thiadiazolin-5-ylidene)acetamide
• N-[5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
• Neptazane
• Neptazaneat
• 5-Acetylimino-4-methyl-delta(sup 2)-1,3,4-thiadiazoline-2-sulfonamide
• Metazolamide [DCIT]
• Methazolamidum [INN-Latin]
• Methazolamidum
• 4-27-00-08221 (Beilstein Handbook Reference)
• UNII-W733B0S9SD
• Acetamide, N-(5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene)-
• Metazolamida [INN-Spanish]
• BRN 0232387
• N-(4-Methyl-2-sulfamoyl-delta(sup 2)-1,3,4-thiadiazolin-5-ylidene)acetamide
• N-[(2E)-3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
• Acetamide, N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]-
• 2-Acetylimino-3-methyl-delta(sup 4)-1,3,4-thiadiazoline-5-sulfonamide
• HSDB 3269
• Methazolamide [INN:BAN:JAN]
• N-[(2Z)-3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
• Acetamide, N-(4-methyl-2-sulfamoyl-delta(sup 2)-1,3,4-thiadiazolin-5-ylidene)-

Methazolamide

CAS: 554-57-4

Sulfonamides used as drugs

• Formula: C₅H₈N₄O₃S₂
• Color and Shape: White Yellow Powder
• Molecular weight: 236.00378

Methazolamide

CAS: 554-57-4

Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and …

• Formula: C₅H₈N₄O₃S₂
• Purity: 98.45% - 99.77%
• Color and Shape: Crystals From Water Solid
• Molecular weight: 236.27

Methazolamide

CAS: 554-57-4

• Formula: C₅H₈N₄O₃S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 236.272

Methazolamide-d6

CAS: 554-57-4

• Formula: C₅H₂D₆N₄O₃S₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 242.30

Methazolamide

CAS: 554-57-4

• Purity: 98%
• Molecular weight: 236.27g/mol

Methazolamide

CAS: 554-57-4

• Formula: C₅H₈N₄O₃S₂
• Molecular weight: 236.27

Methazolamide

CAS: 554-57-4

• Purity: 99.96%
• Molecular weight: 236.27g/mol

Methazolamide

CAS: 554-57-4

• Formula: C₅H₈N₄O₃S₂
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 236.26

Methazolamide

CAS: 554-57-4

• Formula: C₅H₈N₄O₃S₂
• Color and Shape: White Solid
• Molecular weight: 236.27

Methazolamide

CAS: 554-57-4

Applications Methazolamide is a carbonic anhydrase inhibitor. Methazolamide is used in the treatment of glaucoma. …

• Formula: C₅H₈N₄O₃S₂
• Color and Shape: Neat
• Molecular weight: 236.27

Methazolamide

CAS: 554-57-4

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 236.26

Methazolamide

CAS: 554-57-4

Methazolamide is a drug that is used to treat eye disorders by reducing the production …

• Formula: C₅H₈N₄O₃S₂
• Purity: Min. 95%
• Molecular weight: 236.27 g/mol