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CAS 554-57-4

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Methazolamide

Description:
Methazolamide is a carbonic anhydrase inhibitor primarily used in the treatment of glaucoma and certain types of edema. It is a sulfonamide derivative, characterized by its ability to reduce intraocular pressure by decreasing the production of aqueous humor in the eye. The chemical formula of methazolamide is C4H6N4O3S, and it features a sulfonamide group, which is essential for its pharmacological activity. Methazolamide is typically administered orally and is known for its relatively rapid onset of action. Its solubility in water is moderate, which influences its bioavailability. Common side effects may include metabolic acidosis, electrolyte imbalances, and gastrointestinal disturbances. Due to its mechanism of action, methazolamide can also lead to increased urinary excretion of bicarbonate, which may result in a decrease in blood pH. As with any medication, it is important for patients to consult healthcare professionals for appropriate dosing and potential interactions with other drugs.
Formula:C5H8N4O3S2
InChI:InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)
InChI key:InChIKey=FLOSMHQXBMRNHR-UHFFFAOYSA-N
SMILES:N(C(C)=O)=C1SC(S(N)(=O)=O)=NN1C
Synonyms:
  • 5-Acetylimino-4-methyl-Δ2-1,3,4-thiadiazoline-2-sulfonamide
  • 5-Acetylimino-4-methyl-Δ<sup>2</sup>-1,3,4-thiadiazoline-2-sulfonamide
  • Acetamide, N-(4-methyl-2-sulfamoyl-Δ2-1,3,4-thiadiazolin-5-ylidene)-
  • Acetamide, N-(4-methyl-2-sulfamoyl-Δ<sup>2</sup>-1,3,4-thiadiazolin-5-ylidene)-
  • L 584601
  • Metazolamida
  • Metazolamide
  • Methazolamid
  • Methazolamide
  • Methenamide
  • See more synonyms
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