CAS 55750-63-5

N-(6-Maleimidocaproyloxy)succinimide

Description:

N-(6-Maleimidocaproyloxy)succinimide, with the CAS number 55750-63-5, is a chemical compound commonly used in bioconjugation and protein labeling applications. It features a maleimide functional group, which is known for its ability to selectively react with thiol groups in proteins and peptides, facilitating the formation of stable thioether bonds. This compound is characterized by its succinimide moiety, which enhances its solubility and reactivity in aqueous environments. Typically, it appears as a white to off-white solid and is soluble in organic solvents like dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). The presence of the maleimide group allows for site-specific conjugation, making it valuable in the development of targeted drug delivery systems, biosensors, and diagnostic tools. Additionally, its stability under physiological conditions makes it suitable for various biochemical applications. Proper handling and storage conditions are essential to maintain its reactivity and prevent degradation.

Formula: C₁₄H₁₆N₂O₆

InChI: InChI=1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2

InChI key: InChIKey=VLARLSIGSPVYHX-UHFFFAOYSA-N

SMILES: O(C(CCCCCN1C(=O)C=CC1=O)=O)N2C(=O)CCC2=O

Synonyms:

• 1-{6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione
• 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
• 1H-Pyrrole-2,5-dione, 1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-
• 2,5-Dioxopyrrolidin-1-yl 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate
• 6-Maleimidohexanoic acid N-hydroxysuccinimide ester
• 6-Maleimidohexanoic acid N-succinimidyl ester
• N-(6-Maleimide caproyloxy) succinimide
• N-(6-Maleimideocaproyloxy)succinimide
• N-(6-Maleimidocaproyloxy)succinimide
• N-(epsilon-Maleimidocaproyloxy)succinimide
• N-(ε-Maleimidocaproyloxy)succinimide
• N-Succinimidyl 6-maleimidohexanoate

6-Maleimidocaproic acid N-succinimidyl ester, 95%

CAS: 55750-63-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₄H₁₆N₂O₆

Purity: 95%

Molecular weight: 308.29

Ref: 02-H65996

N-Succinimidyl 6-maleimidohexanoate

CAS: 55750-63-5

Formula: C₁₄H₁₆N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 308.2866

Ref: IN-DA003TCH

EMCS

CAS: 55750-63-5

EMCS

Purity: ≥98%

Molecular weight: 308.29g/mol

Ref: 54-BUP15806

N-(E-Maleimidocaproyloxy)succinimide

CAS: 55750-63-5

N-(E-Maleimidocaproyloxy)succinimide

Formula: C₁₄H₁₆N₂O₆

Purity: By hplc: 99.2% (Typical Value in Batch COA)

Color and Shape: white to off-white solid

Molecular weight: 308.29g/mol

Ref: 54-BICL222

N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent]

CAS: 55750-63-5

Formula: C₁₄H₁₆N₂O₆

Purity: >98.0%(N)

Color and Shape: White to Light yellow powder to crystaline

Molecular weight: 308.29

Ref: 3B-S0428

N-(6-Maleimidocaproyloxy)succinimide

CAS: 55750-63-5

Formula: C₁₄H₁₆N₂O₆

Molecular weight: 308.29

Ref: 4Z-A-4619

EMCS

CAS: 55750-63-5

EMCS is a heterobifunctional crosslinker for hapten, enzyme conjugates, and ADC protective groups.

Formula: C₁₄H₁₆N₂O₆

Purity: 99.37% - 99.88%

Color and Shape: White To Cream Colored Crystals

Molecular weight: 308.29

Ref: TM-T14061

N-Succinimidyl 6-maleimidohexanoate

CAS: 55750-63-5

Formula: C₁₄H₁₆N₂O₆

Purity: 98%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 308.29

Ref: 10-F079601

N-(ε-Maleimidocaproyloxy) Succinimide extrapure, 98%

CAS: 55750-63-5

Formula: C₁₄H₁₆N₂O₆

Molecular weight: 308.29

Ref: SR-50062

N-Succinimidyl 6-Maleimidohexanoate

Controlled Product

CAS: 55750-63-5

Applications N-SUCCINIMIDYL 6-MALEIMIDOHEXANOATE (cas# 55750-63-5) is a useful research chemical.

Formula: C₁₄H₁₆N₂O₆

Color and Shape: Neat

Molecular weight: 308.28

Ref: TR-S688065

N-Succinimidyl 6-Maleimidohexanoate

CAS: 55750-63-5

Formula: C₁₄H₁₆N₂O₆

Molecular weight: 308.29

Ref: ST-EA-CP-A18014

6-Maleimidocaproic acid N-hydroxysuccinimide ester

CAS: 55750-63-5

6-Maleimidocaproic acid N-hydroxysuccinimide ester (6MCA-NHS) is a fluorescent probe that reacts with the hydroxyl group of fatty acids in human serum and other biological samples. 6MCA-NHS binds to the carboxylic acid group at the end of a fatty acid molecule, forming a covalent bond. This process generates light emission that can be detected by a fluorescence probe to measure changes in pH or other chemical properties within the solution. 6MCA-NHS has been used as a tumor treatment, where laser ablation is used to break up tumor cells and release 6MCA-NHS into the cytoplasm. The drug can then bind to DNA molecules and inhibit protein synthesis, which results in cell death.

Formula: C₁₄H₁₆N₂O₆

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 308.29 g/mol

Ref: 3D-FM48296