CAS 5579-84-0: Betahistine dihydrochloride
Description:Betahistine dihydrochloride is a histamine analog primarily used in the treatment of Ménière's disease and other vestibular disorders. It acts as a selective agonist for histamine H1 receptors and an antagonist for H3 receptors, which helps to improve blood flow in the inner ear and reduce symptoms such as vertigo and tinnitus. The substance is typically administered in oral form and is known for its relatively good bioavailability. Chemically, it is characterized by its dihydrochloride salt form, which enhances its solubility in water. Betahistine dihydrochloride is generally well-tolerated, with common side effects including gastrointestinal disturbances and headaches. Its mechanism of action involves modulation of neurotransmitter release and enhancement of microcirculation in the inner ear, contributing to its therapeutic effects. The compound is classified under the category of antihistamines, although it does not exhibit the sedative properties commonly associated with many other drugs in this class. Overall, Betahistine dihydrochloride is a valuable medication for managing balance disorders related to inner ear dysfunction.
Formula:C8H12N2·2ClH
InChI:InChI=1S/C8H12N2.2ClH/c1-9-7-5-8-4-2-3-6-10-8;;/h2-4,6,9H,5,7H2,1H3;2*1H
InChI key:InChIKey=XVDFMHARQUBJRE-UHFFFAOYSA-N
SMILES:Cl.N=1C=CC=CC1CCNC
- Synonyms:
- 2-Pyridineethanamine, N-methyl-, dihydrochloride
- 2-Pyridineethanamine, N-methyl-, hydrochloride (1:2)
- Betahistine dihydrochloride
- Betahistine hydrochloride
- Betaserc
- N-methyl-2-(pyridin-2-yl)ethanamine dihydrochloride
- Pyridine, 2-[2-(methylamino)ethyl]-, dihydrochloride
- Sinmenier
- Vasomotal
- PT 9
- See more synonyms

Betahistine dihydrochloride
Ref: 47-824
100mg | 242.00 € |

Betahistine dihydrochloride CRS
Ref: 41-Y0000391
50mg | 115.00 € |

Betahistine Hydrochloride
Ref: 45-1065618
200mg | 463.00 € |

2-Pyridineethanamine, N-methyl-, dihydrochloride
Ref: IN-DA00I9YC
1g | 49.00 € | ||
5g | 80.00 € | ||
25g | 186.00 € | ||
100g | 550.00 € |

Betahistine DiHCl
Ref: 4Z-B-368
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |

Ref: 54-OR1012385
1g | 32.00 € | ||
5g | 61.00 € | ||
25g | 206.00 € | ||
100g | 614.00 € | ||
500g | 2,273.00 € |

Betahistine-13C-d3 DiHCl
Ref: 4Z-B-364
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |

2-(2-(Methylamino)ethyl)pyridine dihydrochloride, 99%
Ref: AC-16799
1g | To inquire | ||
5g | To inquire |

Betahistine Dihydrochloride
Ref: 86-MM0587.00-0250
250mg | 1,250.00 € |

Betahistine dihydrochloride
Ref: TM-T0246
1g | 34.00 € | ||
1mL*10mM (DMSO) | 34.00 € |

Betahistine Dihydrochloride
Ref: TR-B324001
1g | 108.00 € | ||
5g | 143.00 € | ||
100mg | 101.00 € |

N-methyl-N-(2-pyridin-2-ylethyl)amine dihydrochloride
Ref: 10-F351346
1g | To inquire | ||
5g | 91.00 € | ||
10g | To inquire | ||
25g | 115.00 € | ||
100g | 401.00 € |

Betahistine dihydrochloride
Ref: 3D-FB138972
50g | 311.00 € | ||
100g | 464.00 € | ||
250g | 742.00 € | ||
25kg | 14,522.00 € | ||
500g | 1,055.00 € |