CAS 55985-32-5

Nicardipine

Description:

Nicardipine is a calcium channel blocker primarily used in the management of hypertension and angina pectoris. It belongs to the dihydropyridine class of medications, which work by inhibiting the influx of calcium ions through L-type calcium channels in vascular smooth muscle and cardiac tissue. This action leads to vasodilation, reducing peripheral vascular resistance and lowering blood pressure. Nicardipine is characterized by its relatively rapid onset of action and a duration that can vary depending on the formulation. It is typically administered orally or intravenously, with the intravenous form often used in acute settings. The chemical structure of nicardipine includes a dihydropyridine ring, which is essential for its pharmacological activity. Additionally, nicardipine has a favorable side effect profile, though it may cause peripheral edema, headache, or flushing in some patients. As with all medications, it is important to monitor for potential interactions with other drugs and to consider patient-specific factors when prescribing nicardipine.

Formula: C₂₆H₂₉N₃O₆

InChI: InChI=1/C26H29N3O6/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19/h5-12,15,24,27H,13-14,16H2,1-4H3

InChI key: InChIKey=ZBBHBTPTTSWHBA-UHFFFAOYSA-N

SMILES: C(OCCN(CC1=CC=CC=C1)C)(=O)C=2C(C(C(OC)=O)=C(C)NC2C)C3=CC(N(=O)=O)=CC=C3

Synonyms:

• (.+-.)-Nicardipine
• 1,4-Dihidro-2,6-Dimetil-4-(M-Nitrofenil)Piridina-3,5-Dicarboxilato De 2-(Bencilmetilamino)Etilo Y Metilo
• 1,4-Dihydro-2,6-Dimethyl-4-(M-Nitrophenyl)Pyridine-3,5-Dicarboxylate De 2-(Benzylmethylamino)Ethyle Et De Methyle
• 2-(Benzylmethylamino)Ethyl Methyl 1,4-Dihydro-2,6-Dimethyl-4-(M-Nitrophenyl)Pyridine-3,5-Dicarboxylate
• 2-(Benzylmethylamino)ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)pyridin-3,5-dicarboxylat
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-[2-[methyl(phenylmethyl)amino]ethyl] ester
• Perpidine
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-[methyl(phenylmethyl)amino]ethyl ester
• Nicardipine (base and/or unspecified salts)
• 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[2-[methyl(benzyl)amino]ethyl]5-methyl ester
• Methyl 2-(benzyl-methyl-amino)ethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl 5-[2-(N-methylbenzylamino)ethyl] ester
• Nicardipine Hcl 54527-84-3/Base
• 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylic acid 3-methyl 5-[2-[methyl(benzyl)amino]ethyl] ester
• 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-[methy(phenyl-methyl)amino]ethyl ester hydrochloride
• benzylmethylamino)ethylmethylester

Nicardipine Hydrochloride

CAS: 54527-84-3, 55985-32-5

Formula: C₂₆H₂₉N₃O₆·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow to Green powder to crystal

Molecular weight: 515.99

Ref: 3B-N0635

Nicardipine

CAS: 55985-32-5

Formula: C₂₆H₂₉N₃O₆

Purity: 98%

Color and Shape: Liquid

Molecular weight: 479.5250

Ref: IN-DA019FS8

Nicardipine

CAS: 55985-32-5

Nicardipine

Purity: ≥98%

Molecular weight: 479.52g/mol

Ref: 54-BUP17547

Nicardipine

CAS: 55985-32-5

Nicardipine

Purity: 98%

Molecular weight: 479.53g/mol

Ref: 54-OR1027879

Nicardipine

CAS: 55985-32-5

Formula: C₂₆H₂₉N₃O₆

Purity: ≥ 98.0%

Color and Shape: White to off-white solid

Molecular weight: 479.52

Ref: 7W-GP0799

Nicardipine

CAS: 55985-32-5

Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.

Formula: C₂₆H₂₉N₃O₆

Purity: 99.56%

Color and Shape: Solid

Molecular weight: 479.52

Ref: TM-T21454

Nicardipine

CAS: 55985-32-5

L-type calcium channel blocker

Formula: C₂₆H₂₉N₃O₆

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 479.53 g/mol

Ref: 3D-FN65103