CAS 56-04-2

Methylthiouracil

Description:

Methylthiouracil, with the CAS number 56-04-2, is an organic compound that belongs to the class of thiouracil derivatives. It is primarily recognized for its role as an antithyroid agent, used in the treatment of hyperthyroidism by inhibiting the synthesis of thyroid hormones. The molecular formula of methylthiouracil is C7H8N2OS, and it features a thiol group, which contributes to its biological activity. This compound is typically presented as a white to off-white crystalline powder, and it is soluble in water and alcohol, making it accessible for various pharmaceutical formulations. Methylthiouracil acts by blocking the enzyme thyroperoxidase, which is crucial for the iodination of tyrosine residues in thyroglobulin, thereby reducing the production of thyroxine (T4) and triiodothyronine (T3). In addition to its therapeutic applications, it is also used in research settings to study thyroid function and related disorders. Safety precautions should be observed when handling this compound, as it can have side effects and interactions with other medications.

Formula: C₅H₆N₂OS

InChI: InChI=1S/C5H6N2OS/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)

InChI key: InChIKey=HWGBHCRJGXAGEU-UHFFFAOYSA-N

SMILES: CC1=CC(=O)NC(=S)N1

Synonyms:

• 2,3-Dihydro-6-methyl-2-thioxo-4(1H)-pyrimidinone
• 2-Mercapto-4-methyl-6-hydroxypyrimidine
• 2-Mercapto-6-methyl-4-pyrimidinol
• 2-Mercapto-6-methylpyrimidin-4(3H)-one
• 2-Mercapto-6-methylpyrimidin-4-one
• 2-Mercapto-6-methylpyrimidyl-4-one
• 2-Thio-6-methyluracil
• 4(1H)-pyrimidinone, 2,3-dihydro-6-methyl-2-thioxo-
• 4-Hydroxy-2-mercapto-6-methylpyrimidine
• 4-Hydroxy-6-methyl-2-mercaptopyrimidine
• 4-Hydroxy-6-methylpyrimidine-2(1H)-thione
• 4-Methyl-2-thiouracil
• 6-(methylsulfanyl)pyrimidine-2,4(1H,3H)-dione
• 6-Methyl-2-Sulfanylpyrimidin-4-Ol
• 6-Methyl-2-Thiouracyle
• 6-Methyl-2-mercaptouracil
• 6-Methyl-2-thio-2,4-(1H,3H)-pyrimidinedione
• 6-Methyl-2-thiouracil
• 6-Methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
• 6-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-on
• 6-Methyl-2-thioxopyrimidin-4-one
• 6-Methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine
• 6-Thio-4-methyluracil
• 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
• Alkiron
• Antibason
• Basecil
• Basethyrin
• MTU
• Metacil
• Methacil
• Methiacil
• Methicil
• Methiocil
• Methiure
• Methylthiouracil
• Methylthiouracile
• Metiltiouracilo
• Metiur
• Muracil
• Muracin
• Nsc 193526
• Nsc 314271
• Nsc 9378
• Orcanon
• Prostrumyl
• Strumacil
• Thimecil
• Thiomecil
• Thiomidil
• Thioryl
• Thiothymin
• Thiothyron
• Thiuryl
• Thyreonorm
• Thyreostat
• Thyreostat I
• Thyril
• Tiomeracil
• Tiorale M
• Tiotiron
• Uracil, 2-Thio-4-Methyl-
• Uracil, 6-methyl-2-thio-

6-Methyl-2-thiouracil, 98%

CAS: 56-04-2

6-Methyl-2-thiouracil is mainly used in surgical preparation of mild hyperthyroidism, thyroid storm, hyperthyroidism and postoperative treatment. It is used in the treatment of hyperthyroidism. It is used as a drug, which is applied to decrease the formation of stored thyroid hormone and thyroglobul

Formula: C₅H₆N₂OS

Purity: 98%

Color and Shape: White to pale yellow, Powder

Molecular weight: 142.18

Ref: 02-A17982

4-Hydroxy-2-mercapto-6-methylpyrimidine

CAS: 56-04-2

Formula: C₅H₆N₂OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 142.1789

Ref: IN-DA0034DF

6-Methyl-2-thiouracil

CAS: 56-04-2

6-Methyl-2-thiouracil

Formula: C₅H₆N₂OS

Purity: ≥95%

Color and Shape: Pale yellow Solid-Crystals

Molecular weight: 142.17894

Ref: 54-OR27585

Methylthiouracil

CAS: 56-04-2

Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.

Formula: C₅H₆N₂OS

Purity: 98.82% - 99.89%

Color and Shape: Solid

Molecular weight: 142.18

Ref: TM-T0304

Methylthiouracil

CAS: 56-04-2

Methylthiouracil

Formula: C₅H₆N₂OS

Purity: ≥98%

Molecular weight: 142.18

Ref: 54-BUP11867

6-Methyl-2-thiouracil

Controlled Product

CAS: 56-04-2

Formula: C₅H₆N₂OS

Color and Shape: White

Molecular weight: 142.18

Ref: 04-C15144300

Methylthiouracil

Controlled Product

CAS: 56-04-2

Formula: C₅H₆N₂OS

Color and Shape: Neat

Molecular weight: 142.18

Ref: 86-MM3148.00

6-Methyl-2-thiouracil

CAS: 56-04-2

Formula: C₅H₆N₂OS

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 142.18

Ref: 3B-M0443

6-​Methyl-​2-​thiouracil

Controlled Product

CAS: 56-04-2

Applications 6-​Methyl-​2-​thiouracil is a derivative of methylthiouracil (M330710), a competitive inhibitor of Nitric Oxide Synthase (NOS). Potential anti-inflammatory agent.
References Palumbo, A. et al.: Biochem. Bioph. Res. Co. 282, 793(2001), Ku, S. et al.: Toxicol. App. Pharmacol., 288, 374 (2015);

Formula: C₅H₆N₂OS

Color and Shape: Neat

Molecular weight: 142.18

Ref: TR-M331355

4-Hydroxy-2-mercapto-6-methy1-pyrimidine

CAS: 56-04-2

4-Hydroxy-2-mercapto-6-methylpyrimidine is a structural analysis of the molecule. It is a pyrimidine compound that has been found to be effective against human bowel disease and congestive heart failure, as well as in a model system of infectious diseases. 4-Hydroxy-2-mercapto-6-methylpyrimidine inhibits the activity of cyclin D2 by binding to it and preventing its attachment to the G1/S phase checkpoint. This compound also inhibits the activity of c. glabrata polymerase chain reaction (PCR) and human leukemia cells HL60 cells. 4-Hydroxy-2-mercapto-6-methylpyrimidine is an analytical method for xray diffraction data, which has been shown to have antibacterial properties due to its ability to inhibit methylthiouracil from being converted into thyroxine in the body.

Formula: C₅H₆N₂OS

Purity: Min. 95%

Color and Shape: White Clear Liquid

Molecular weight: 142.18 g/mol

Ref: 3D-FH34311

Methylthiouracil

CAS: 56-04-2

2-Mercapto-6-methylpyrimidin-4(1H)-one

Formula: C₅H₆N₂OS

Purity: 98%

Molecular weight: 142.18

Ref: IN-DG21473

6-Methyl-2-thiouracil

CAS: 56-04-2

Formula: C₅H₆N₂OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 142.18

Ref: 10-F076835

6-Methyl-2-thiouracil-13C4

Controlled Product

CAS: 56-04-2

Formula: C₄CH₆N₂OS

Color and Shape: Neat

Molecular weight: 146.15

Ref: TR-M331357

Propylthiouracil EP Impurity B

CAS: 56-04-2

Formula: C₅H₆N₂OS

Molecular weight: 142.18

Ref: ST-EA-CP-P201002