CAS 56-75-7

(-)-Chloramphenicol

Description:

(-)-Chloramphenicol, with the CAS number 56-75-7, is a broad-spectrum antibiotic originally derived from the bacterium Streptomyces venezuelae. It is characterized by its ability to inhibit bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome, effectively blocking peptide bond formation. This compound is a white to off-white crystalline powder that is soluble in water and alcohol but has limited solubility in organic solvents. Its molecular formula is C11H12Cl2N2O5, and it has a molecular weight of approximately 323.13 g/mol. (-)-Chloramphenicol exhibits antibacterial activity against a wide range of Gram-positive and Gram-negative bacteria, making it useful in treating various infections. However, its use is limited due to potential side effects, including aplastic anemia and gray baby syndrome in newborns. As a result, it is often reserved for serious infections where other antibiotics are ineffective. Proper handling and dosage are crucial to minimize adverse effects and ensure therapeutic efficacy.

Formula: C₁₁H₁₂Cl₂N₂O₅

InChI: InChI=1/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9?/m1/s1

InChI key: InChIKey=WIIZWVCIJKGZOK-RKDXNWHRSA-N

SMILES: [C@@H]([C@H](NC(C(Cl)Cl)=O)CO)(O)C1=CC=C(N(=O)=O)C=C1

Synonyms:

• 2,2-Dichloro-N-(2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl)-Acetamid
• 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• 2,2-Dichloro-N-[2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl]Acetamide
• 2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• 2,2-dichloro-N-[(1R,2S)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• 2,2-dichloro-N-[(1S,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• Ak-Chlor
• Alficetyn
• Amphenicol
• Amphicol
• Amseclor
• Anacetin
• Aquamycetin
• Austracol
• Bradyoxetin
• CAF
• CAM
• CAP
• CPh
• Catilan
• Chemicetin
• Chemicetina
• Chlomycol
• Chloramex
• Chloramphenicol
• Chloramsaar
• Chlorasol
• Chlorcetin
• Chloricol
• Chlorocaps
• Chlorocid
• Chlorocide
• Chlorocin
• Chloromycetin
• Chloronitrin
• Chloroptic
• Ciplamycetin
• Cloramfen
• Cloramfenicol
• Cloramficin
• Cloramicol
• Clorocyn
• Cloromisan
• Cylphenicol
• D-(-)-Chloramphenicol
• D-(-)-Threo-2,2-Dichloro-N-[Beta-Hydroxy-Alpha-(Hydroxy-Methyl)-P-Nitrophenethyl]Acetamide
• D-(-)-threo-1-(4-Nitrophenyl)-2-dichloroacetamido-1,3-propanediol
• D-(-)-threo-1-p-Nitrophenyl-2-dichloracetamido-1,3-propanediol
• D-(-)-threo-1-p-Nitrophenyl-2-dichloroacetylamino-1,3-propanediol
• D-(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol
• D-(-)-threo-Chloramphenicol
• D-threo-(1R,2R)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol
• D-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol
• Detreomycin
• Embacetin
• Enicol
• Enteromycetin
• Farmicetina
• Fenicol
• Globenicol
• Gloveticol
• Halcetin
• Intramycetin
• Ismicetina
• Juvamycetin
• Kamaver
• Kemicetine
• Klorita
• Leukomyan
• Leukomycin
• Levocin
• Levomicetina
• Levomitsetin
• Levomycetin
• Levoplast
• Levosin
• Levovetin
• Loromisin
• Mastiphen
• Micloretin
• Micoclorina
• Microcetina
• Mychel
• Mychel-Vet
• Mycinol
• Myclocin
• Mycochlorin
• Novomycetin
• Ocuphenicol
• Opclor
• Ophthochlor
• Pantovernil
• Paraxin
• Quemicetina
• Ronphenil
• Septicol
• Sintomicetin
• Sintomicetina
• Soluthor
• Stanomycetin
• Synthomycetin
• Synthomycin
• Tevcocin
• Tifomycine
• Treomicetina
• Unimycetin
• Veticol
• Viceton
• [R-(R*,R*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• D,L-chloramphenicol
• Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-
• nitrophenyl)ethyl]acetamide
• Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-
• 2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-
• D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-4-NITROPHENETHYL]ACETAMIDE
• D-THREO-(-)-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-HYDROXYMETHYL-P-NITROPHENETHYL]ACETAMIDE
• D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-4-NITROPHENYL] ACETAMIDE
• D-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
• D-2-DICHLOROACETAMIDO-1-P-NITRO-PHENYL-1,3-PROPANEDIOL
• [R-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]ethanamide
• D(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE
• D(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXY-METHYL)-P-NITROPHENYLETHYL]ACETAMIDE
• D-(-)-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
• CHLORAMPHENICOLUM
• D-(-)-THREO-2-DICHLOROACETAMIDO-1-[P-NITRO-PHENYL]-1,3-PROPANEDIOL
• ,[theta-(theta,theta)]-
• D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE

Chloramphenicol

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 323.13

Ref: 3B-C2255

(R,R)-Chloramphenicol, 98%

CAS: 56-75-7

(R,R)-chloramphenicol, 56-75-7, is is a broad-spectrum, semisynthetic antibiotic suitable for various cell biology applications. Learn more at Thermo Fisher Scientific.

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: 98%

Color and Shape: White to yellow to cream to grey, Crystals or powder or crystalline powder

Molecular weight: 323.13

Ref: 02-B20841

Chloramphenicol

CAS: 56-75-7

Color and Shape: Neat

Ref: 61-FOR0516.00

Chloramphenicol

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: 97.68%

Color and Shape: Colorless. Oil

Molecular weight: 322.0

Ref: 8R-CL0456

Chloramphenicol

CAS: 56-75-7

Chloramphenicol

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: 99.6%

Color and Shape: Off-White

Molecular weight: 322.01233

Ref: 47-854

CHLORAMPHENICOL FOR PEAK IDENTIFICATION CRS

CAS: 56-75-7

CHLORAMPHENICOL FOR PEAK IDENTIFICATION CRS

Formula: C₁₁H₁₂Cl₂N₂O₅

Color and Shape: White. Whitish. Crystalline Powder. Powder.

Molecular weight: 323.1294

Ref: 41-Y0001869

CHLORAMPHENICOL CRS

CAS: 56-75-7

CHLORAMPHENICOL CRS

Ref: 41-C1200000

CHLORAMPHENICOL RS

CAS: 56-75-7

CHLORAMPHENICOL RS

Formula: C₁₁H₁₂Cl₂N₂O₅

Molecular weight: 323.1294

Ref: 41-ICRS0241

Chloramphenicol

CAS: 56-75-7

Chloramphenicol and its derivatives; salts thereof

Formula: C₁₁H₁₂Cl₂N₂₀₅

Color and Shape: White Powder

Molecular weight: 3084.66178

Ref: 45-1107004

Chloramphenicol

CAS: 56-75-7

Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: 99.6% - 99.84%

Color and Shape: Needles Or Elongated Plates From Water Or Ethylene Dichloride Solid

Molecular weight: 323.13

Ref: TM-T1205

Chloramphenicol-d4

CAS: 56-75-7

Formula: C₁₁H₈D₄Cl₂N₂O₅

Color and Shape: Pale Yellow Solid

Molecular weight: 327.15

Ref: 4Z-C-10103

Chloramphenicol

CAS: 56-75-7

Chloramphenicol

Purity: ≥98%

Molecular weight: 323.13g/mol

Ref: 54-BUP18539

Chloramphenicol, Ph. Eur. grade

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: (dried basis) 98.0 - 102.0 %

Color and Shape: A white, greyish-white or yellowish-white, fine, crystalline powder or crystals

Molecular weight: 323.14

Ref: 7W-GP6451

Chloramphenicol

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: 98.5 - 101.5 % (dried basis)

Color and Shape: White to light-yellow crystalline powder

Molecular weight: 323.14

Ref: 7W-GA0258

Chloramphenicol, USP grade, low endotoxin

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: 97.0 - 103.0 %

Color and Shape: White to light-yellow crystalline powder

Molecular weight: 323.14

Ref: 7W-GX2600

Chloramphenicol

Controlled Product

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Color and Shape: Neat

Molecular weight: 323.13

Ref: 86-MM0516.00

Chloramphenicol

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: 97.0%

Color and Shape: Solid, Powder or Crystalline Powder or Needles

Molecular weight: 323.13

Ref: 10-F492377

Chloramphenicol 10 µg/mL in Acetonitrile

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Color and Shape: Single Solution

Molecular weight: 323.13

Ref: 04-L11120000AL

Chloramphenicol

Controlled Product

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Color and Shape: Neat

Molecular weight: 323.13

Ref: 04-C11120000

Chloramphenicol 100 µg/mL in Ethyl acetate

Controlled Product

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Color and Shape: Single Solution

Molecular weight: 323.13

Ref: 04-XA11120000EA

Chloramphenicol

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Molecular weight: 323.13

Ref: 4Z-C-10102

Chloramphenicol, USP grade

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: 97.0 - 103.0 %

Color and Shape: White to light-yellow crystalline powder

Molecular weight: 323.14

Ref: 7W-GA0505

Chloramphenicol

CAS: 56-75-7

Chloramphenicol

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: >99%

Color and Shape: solid

Molecular weight: 323.13g/mol

Ref: 54-BIC0113

Chloramphenicol (10mg/ml)

CAS: 56-75-7

Chloramphenicol (10mg/ml)

Color and Shape: Solution

Molecular weight: 323.13g/mol

Ref: 54-BIG1028

Chloramphenicol-d5

Controlled Product

CAS: 56-75-7

Applications Chloramphenicol-d5, is the labeled analogue of Chloramphenicol (C325030), which has a broad spectrum of activity against Gram-positive and gram-negative bacteria. It is also antibacterial, and antirickettsial.
References Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),

Formula: C₁₁H₇D₅Cl₂N₂O₅

Color and Shape: Off-White

Molecular weight: 328.16

Ref: TR-C325033

Chloramphenicol

Controlled Product

CAS: 56-75-7

Applications Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.
References Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),

Formula: C₁₁H₁₂Cl₂N₂O₅

Color and Shape: Neat

Molecular weight: 323.13

Ref: TR-C325030

Chloramphenicol-d5 (100Mug/mL in Acetonitrile)

Controlled Product

CAS: 56-75-7

Formula: C₁₁H₇D₅Cl₂N₂O₅

Color and Shape: Colourless

Molecular weight: 328.16

Ref: TR-KIT8327

Chloramphenicol

CAS: 56-75-7

Chloramphenicol is produced by Streptomyces venezuelae. It is a broad-spectrum antibiotic with bacteriostatic properties. It interferes with bacterial protein synthesis by reversibly binding to the 50S ribosome unit. Used as substrate in the CAT (chloramphenicol acetyl transferase) assay, where the CAT gene expression is monitored by the ability of a system to transform chloramphenicol into acetyl chloramphenicol, which can be followed by simple thin layer chromatography. It is employed in VTM to prevent bacterial growth during specimen storage and transportation.

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 323.13 g/mol

Ref: 3D-AC09460

Chloramphenicol (CFP) for tissue culture, 98-102%

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: 98 - 102%

Color and Shape: White to pale yellow, Crystalline powder, Clear

Molecular weight: 323.1

Ref: SR-28812

Chloramphenicol (CFP), 98-102%

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: min. 98-102%

Color and Shape: White to pale yellow, Crystalline powder, Clear

Molecular weight: 323.1

Ref: SR-97686

Chloramphenicol cell culture, 99%, Endotoxin (BET) 0.2 EU/mg

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Molecular weight: 323.1

Ref: SR-17796

Chloramphenicol (CFP) ExiPlus, Multi-Compendial, 98.0-102%

CAS: 56-75-7

Formula: C₁₁H₁₂Cl₂N₂O₅

Purity: 98.0-102%

Color and Shape: White to pale yellow, Crystalline powder or fine crystals, Clear

Molecular weight: 323.1

Ref: SR-57956