CAS 56124-62-0: Valrubicin

Formula: C₃₄H₃₆F₃NO₁₃

InChI: InChI=1S/C34H36F3NO13/c1-4-5-9-21(40)49-13-20(39)33(47)11-16-24(19(12-33)51-22-10-17(27(41)14(2)50-22)38-32(46)34(35,36)37)31(45)26-25(29(16)43)28(42)15-7-6-8-18(48-3)23(15)30(26)44/h6-8,14,17,19,22,27,41,43,45,47H,4-5,9-13H2,1-3H3,(H,38,46)/t14-,17-,19-,22-,27+,33-/m0/s1

InChI key: InChIKey=ZOCKGBMQLCSHFP-KQRAQHLDSA-N

SMILES: O=C1C=2C=CC=C(OC)C2C(=O)C=3C(O)=C4C(=C(O)C13)CC(O)(C(=O)COC(=O)CCCC)CC4OC5OC(C)C(O)C(NC(=O)C(F)(F)F)C5

Synonyms:

• AD 32
• Pentanoic acid, 2-[(2S,4S)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-2-naphthacenyl]-2-oxoethyl ester
• Pentanoic acid, 2-[(2S,4S)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-2-naphthacenyl]-2-oxoethyl ester
• Pentanoic acid, 2-[1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-2-naphthacenyl]-2-oxoethyl ester, (2S-cis)-
• Antibiotic AD 32

Valrubicin

CAS: 56124-62-0

Antibiotics nesoi

• Formula: C₃₄H₃₆F₃NO₁₃
• Color and Shape: Orange Red Crystalline Powder
• Molecular weight: 723.65 g/mol

Valrubicin

CAS: 56124-62-0

• Formula: C₃₄H₃₆F₃NO₁₃
• Purity: 95.0 - 103.0 % (dried basis)
• Color and Shape: Orange to orange-red crystalline powder
• Molecular weight: 723.64

Valrubicin

CAS: 56124-62-0

Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) …

• Formula: C₃₄H₃₆F₃NO₁₃
• Purity: 97.41%
• Color and Shape: Solid
• Molecular weight: 723.64

Valrubicin

CAS: 56124-62-0

Applications Chemotherapy drug used to treat cancer of the bladder. References Steinberg, G., et al.: …

• Formula: C₃₄H₃₆F₃NO₁₃
• Color and Shape: Red Solid
• Molecular weight: 723.64

Valrubicin

CAS: 56124-62-0

Chemotherapy for bladder cancer; semi-synthetic analog of doxorubicin

• Formula: C₃₄H₃₆F₃NO₁₃
• Purity: Min. 95 Area-%
• Color and Shape: Powder
• Molecular weight: 723.64 g/mol