CAS 56180-94-0
:Acarbose
Description:
Acarbose is an alpha-glucosidase inhibitor primarily used in the management of type 2 diabetes mellitus. It functions by delaying the digestion and absorption of carbohydrates in the intestine, thereby reducing postprandial blood glucose levels. Acarbose is a complex oligosaccharide derived from the fermentation of the bacterium Actinoplanes utahensis. Its molecular formula is C25H43NO18, and it has a molecular weight of approximately 645.6 g/mol. The substance is typically administered orally and is known for its gastrointestinal side effects, including flatulence and diarrhea, due to the fermentation of undigested carbohydrates by intestinal bacteria. Acarbose is often used in conjunction with other antidiabetic medications to enhance glycemic control. It is important for patients to adhere to dietary recommendations while using acarbose to maximize its efficacy and minimize adverse effects. As with any medication, monitoring for potential interactions and contraindications is essential for safe and effective use.
Formula:C25H43NO18
InChI:InChI=1S/C25H43NO18/c1-7-13(26-9-2-8(3-27)14(33)18(37)15(9)34)17(36)20(39)24(41-7)44-23-12(6-30)42-25(21(40)19(23)38)43-22(11(32)5-29)16(35)10(31)4-28/h2,4,7,9-27,29-40H,3,5-6H2,1H3/t7-,9+,10+,11-,12-,13-,14-,15+,16-,17+,18+,19-,20-,21-,22-,23-,24-,25-/m1/s1
InChI key:InChIKey=CEMXHAPUFJOOSV-XGWNLRGSSA-N
SMILES:O([C@@H]1[C@@H](CO)O[C@H](O[C@@H]([C@@H]([C@H](C=O)O)O)[C@@H](CO)O)[C@H](O)[C@H]1O)[C@@H]2[C@H](O)[C@@H](O)[C@H](N[C@H]3C=C(CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](C)O2
Synonyms:- (2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enyl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal
- 4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}Hexopyranosyl-(1->4)Hexopyranosyl-(1->4)Hexopyranose
- 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-D-glucopyranose
- 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-beta-D-glucopyranose
- 4,6-dideoxy-4-{[(1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-beta-D-glucopyranose
- <span class="text-smallcaps">D</smallcap>-Glucose, O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-O-α-<smallcap>D</span>-glucopyranosyl-(1→4)-
- <span class="text-smallcaps">D</smallcap>-Glucose, O-4,6-dideoxy-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-O-α-<smallcap>D</span>-glucopyranosyl-(1→4)-, [1S-(1α,4α,5β,6α)]-
- Acarbosa
- Acarviostatin I01
- Arcabose
- Ascarbose
- BAY-g 5421
- D-Glucose, O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-
- D-Glucose, O-4,6-dideoxy-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-, [1S-(1α,4α,5β,6α)]-
- Glucobay
- O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→4)-O-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-<smallcap>D</span>-glucose
- Prandase
- Precose
- Acarbose
- See more synonyms
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Found 19 products.
Acarbose
CAS:Formula:C25H43NO18Purity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:645.61Acarbose, 95%
CAS:A reversible alpha-glucosidase inhibitorFormula:C25H43NO18Purity:95%Molecular weight:645.61ACARBOSE FOR PEAK IDENTIFICATION CRS
CAS:ACARBOSE FOR PEAK IDENTIFICATION CRSFormula:C25H43NO18Molecular weight:645.6048ACARBOSE FOR IDENTIFICATION CRS
CAS:ACARBOSE FOR IDENTIFICATION CRSFormula:C25H43NO18Molecular weight:645.6048Acarbose
CAS:Heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormula:C25H43NO18Color and Shape:White Off-White Amorphous PowderMolecular weight:645.24801Ref: IN-DA00IA14
1kgTo inquire500gTo inquire250mg39.00€1g63.00€5g120.00€10g208.00€25g255.00€250g503.00€Acarbose
CAS:Acarbose (BAY g 5421) is a hypoglycemic agent that is an inhibitor of orally active alpha-glucosidase (IC50=11 nM). High-Quality, Low-Cost!Formula:C25H43NO18Purity:98% - 99.88%Color and Shape:Amorphous Powder SolidMolecular weight:645.60Acarbose, EP grade
CAS:Formula:C25H43NO18Purity:≤ 0.2%Color and Shape:White to light-yellow powderMolecular weight:645.61Acarbose
CAS:Formula:C25H43NO18Purity:96.0 - 102.0 % (anhydrous basis)Color and Shape:White to off-white powderMolecular weight:645.61Acarbose (Acarbosum) (Mixture of Diastereomers)
CAS:Formula:C25H43NO18Color and Shape:White To Off-White SolidMolecular weight:645.61Acarbose
CAS:Stability Hygroscopic
Applications Acarbose is used as an anti-diabetic (1).
References (1) Sailor, D., et al.: Arzneimittel-Forshc., 30, 2182 (1981)Formula:C25H43NO18Color and Shape:Off-WhiteMolecular weight:645.6Acarbose
CAS:Competitive, reversible inhibitor of α-glucosidases used for the control of postprandial hyperglycaemia in patients with type 2 diabetes mellitus. It inhibits digestive enzymes with α-glucosidase activity, which breakdown complex sugars to absorbable monosaccharides. It also reduces the levels of glycated haemoglobin (HbA1c).
Formula:C25H43NO18Purity:Min. 95.0%Color and Shape:White PowderMolecular weight:645.62 g/molAcarbose extrapure, 95%
CAS:Formula:C25H43NO18Purity:min. 95%Color and Shape:White to yellow, PowderMolecular weight:645.62
