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CAS 56287-74-2

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Afloqualone

Description:
Afloqualone is a synthetic compound classified as a quinazolinone derivative, primarily known for its muscle relaxant and anxiolytic properties. It is characterized by its ability to act as a central nervous system depressant, which makes it effective in treating conditions such as muscle spasms and anxiety. The chemical structure of Afloqualone includes a quinazoline ring, which contributes to its pharmacological activity. It is typically administered in oral form and has been studied for its potential therapeutic effects, although its use may be limited due to side effects and regulatory status in various countries. The compound has a moderate lipophilicity, influencing its absorption and distribution in biological systems. Additionally, Afloqualone's mechanism of action involves modulation of neurotransmitter systems, particularly GABAergic pathways, which are crucial for its sedative and muscle-relaxing effects. As with many pharmaceuticals, careful consideration of dosage and potential interactions with other medications is essential for safe use.
Formula:C16H14FN3O
InChI:InChI=1/C16H14FN3O/c1-10-4-2-3-5-14(10)20-15(9-17)19-13-7-6-11(18)8-12(13)16(20)21/h2-8H,9,18H2,1H3
InChI key:InChIKey=VDOSWXIDETXFET-UHFFFAOYSA-N
SMILES:C(F)C=1N(C(=O)C=2C(N1)=CC=C(N)C2)C3=C(C)C=CC=C3
Synonyms:
  • (2-Tolyl)-3H-quinazolin-4-one
  • 4(3H)-quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-
  • 6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone
  • 6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4(3H)-one
  • 6-Amino-2-Fluoromethyl-3-
  • Aroft
  • Arofuto
  • H 495
  • Hq 495
  • 6-Amino-2-Fluoromethyl-3-
  • See more synonyms
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Found 4 products.
  • 4(3H)-Quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-
    Indagoo
    + Info

    4(3H)-Quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-

    CAS:
    Formula:C16H14FN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:283.3003

    Ref: IN-DA00IA22

    100mg
    140.00€
    250mg
    202.00€
    500mg
    322.00€
  • Afloqualone
    Targetmol
    + Info

    Afloqualone

    CAS:
    <p>Afloqualone (HQ-495) is a GABA Receptor agonist with sedative and muscle-relaxant properties.</p>
    Formula:C16H14FN3O
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:283.3

    Ref: TM-T4993

  • Afloqualone
    TRC
    + Info

    Afloqualone

    CAS:
    <p>Applications Afloqualone acts as a muscle relaxant in humans and may be used in the treatment of muscle spasms affecting rheumatoid arthritis.<br>References Farkas, S. et al.: J. Pharm. Toxicol. Meth., 52, 264 (2005); Yun, H. et al.: Talanta, 73, 635 (2007);<br></p>
    Formula:C16H14FN3O
    Color and Shape:White To Off-White
    Molecular weight:283.30

    Ref: TR-A357700

    250mg
    171.00€
  • 6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one
    Biosynth
    + Info

    6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one

    Controlled Product
    CAS:
    <p>6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one is a potent inhibitor of the enzyme dihydrofolate reductase, which is required for the synthesis of DNA and other macromolecules. It has been shown to inhibit the growth of cutaneous lesions in mice and rats. The compound has also been found to be effective against renal lesions (caused by cevimeline hydrochloride) in rats. The compound has a high inhibitory dose as it binds tightly with divalent metal ions such as magnesium, calcium, and zinc. This property may result in its use as an anticancer drug.<br>6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one is soluble in water and polymeric matrices and can be administered orally or intravenously.</p>
    Formula:C16H14FN3O
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:283.3 g/mol

    Ref: 3D-FA29178

    1g
    713.00€
    50mg
    135.00€
    100mg
    183.00€
    250mg
    382.00€
    500mg
    509.00€