CAS 56341-08-3: Mabuterol
Description:Mabuterol is a synthetic compound classified as a beta-adrenergic agonist, primarily used for its bronchodilator properties in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It functions by stimulating beta-2 adrenergic receptors in the smooth muscle of the airways, leading to relaxation and dilation of bronchial passages, which facilitates easier breathing. Mabuterol is characterized by its relatively selective action on beta-2 receptors, minimizing cardiovascular side effects commonly associated with non-selective beta agonists. The compound is typically administered via inhalation to achieve localized effects in the lungs while reducing systemic exposure. Its pharmacokinetics include a rapid onset of action, making it suitable for acute relief of bronchospasm. As with other beta-agonists, potential side effects may include tremors, palpitations, and increased heart rate, particularly at higher doses. Overall, Mabuterol represents a valuable therapeutic option in managing airway constriction in patients with obstructive pulmonary diseases.
Formula:C13H18ClF3N2O
InChI:InChI=1S/C13H18ClF3N2O/c1-12(2,3)19-6-10(20)7-4-8(13(15,16)17)11(18)9(14)5-7/h4-5,10,19-20H,6,18H2,1-3H3
InChI key:InChIKey=JSJCTEKTBOKRST-UHFFFAOYSA-N
SMILES:FC(F)(F)C1=CC(=CC(Cl)=C1N)C(O)CNC(C)(C)C
- Synonyms:
- 1-[4-Amino-3-Chloro-5-(Trifluoromethyl)Phenyl]-2-(Tert-Butylamino)Ethanol
- 4-Amino-3-chloro-α-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)benzenemethanol
- 4-Amino-alpha-((tert-butylamino)methyl)-3-chloro-5-(trifluoromethyl)benzyl alcohol
- Ambuterol
- Benzenemethanol, 4-amino-3-chloro-alpha-(((1,1-dimethylethyl)amino)methyl)-5-(trifluoromethyl)-
- Benzenemethanol, 4-amino-3-chloro-α-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)-
- Ccris 5288
- Mabuterol [INN]
- Mabuterolum
- Mabuterolum [INN-Latin]
- See more synonyms
- PB 868Cl
- Unii-R4K19W6S7Q
- Mabuterol