CAS 564-37-4

Ergocorninine

Description:

Ergocorninine is a naturally occurring alkaloid derived from the ergot fungus, specifically from the species of the genus Claviceps. It is classified as a member of the ergot alkaloids, which are known for their complex structures and diverse biological activities. Ergocorninine is characterized by its bicyclic structure, which includes a tetracyclic core typical of many ergot alkaloids. This compound exhibits various pharmacological properties, including vasoconstriction and potential effects on neurotransmitter systems, making it of interest in both medicinal chemistry and pharmacology. Ergocorninine has been studied for its potential therapeutic applications, particularly in the treatment of migraine and other vascular disorders. However, due to its potent biological effects, it must be handled with caution, as it can also lead to adverse effects. Its CAS number, 564-37-4, is a unique identifier that facilitates the identification and study of this compound in scientific literature and databases.

Formula: C₃₁H₃₉N₅O₅

InChI: InChI=1S/C31H39N5O5/c1-16(2)26-28(38)35-11-7-10-24(35)31(40)36(26)29(39)30(41-31,17(3)4)33-27(37)19-12-21-20-8-6-9-22-25(20)18(14-32-22)13-23(21)34(5)15-19/h6,8-9,12,14,16-17,19,23-24,26,32,40H,7,10-11,13,15H2,1-5H3,(H,33,37)/t19-,23+,24-,26-,30+,31-/m0/s1

InChI key: InChIKey=UJYGDMFEEDNVBF-KMKPOGODSA-N

SMILES: O[C@]12N(C(=O)[C@@](NC(=O)[C@H]3C=C4C=5C=6C(C[C@]4(N(C)C3)[H])=CNC6C=CC5)(C(C)C)O1)[C@@H]([C@@H](C)C)C(=O)N7[C@]2(CCC7)[H]

Synonyms:

• (5'Alpha,8Alpha)-12'-Hydroxy-2',5'-Bis(1-Methylethyl)-3',6',18-Trioxoergotaman
• (5Alpha,5'Beta)-12'-Hydroxy-3',6',18-Trioxo-2',5'-Di(Propan-2-Yl)Ergotaman
• (5′α,8α)-12′-Hydroxy-2′,5′-bis(1-methylethyl)ergotaman-3′,6′,18-trione
• (8alpha)-12'-Hydroxy-2',5'alpha-diisopropylergotaman-3',6',18-trione
• 8-Epiergocornine
• 8-Isoergocornine
• 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotaman-3′,6′,18-trione deriv.
• Ergocorninine
• Ergotaman-3',6',18-trione, 12'-hydroxy-2',5'-bis(1-methylethyl)-, (5'alpha,8alpha)-
• Ergotaman-3′,6′,18-trione, 12′-hydroxy-2′,5′-bis(1-methylethyl)-, (5′α,8α)-
• Indolo[4,3-fg]quinoline, ergotaman-3′,6′,18-trione deriv.

Ergocorninine

Controlled Product

CAS: 564-37-4

Formula: C₃₁H₃₉N₅O₅

Color and Shape: Neat

Molecular weight: 561.67

Ref: 04-C13201210

Ergocorninine

CAS: 564-37-4

Formula: C₃₁H₃₉N₅O₅

Molecular weight: 561.68

Ref: 4Z-E-185001

Ergocorninine

Controlled Product

CAS: 564-37-4

Ergocorninine is a natural alkaloid that has been shown to have receptor activity in the brain, and has been found to be a dopamine agonist. Ergocorninine is also an antagonist of the estrogen receptor. The wild-type strain of ergocryptine was used for the analysis of ergocorninine. A model system was used to study the matrix effect on analytical methods. Alkaloids were analyzed using a dispersive solid-phase extraction method and serum prolactin levels were studied by administering estradiol benzoate to vivo models.

Formula: C₃₁H₃₉N₅O₅

Purity: Min. 95%

Molecular weight: 561.7 g/mol

Ref: 3D-XE180552

8-Isoergocornine

CAS: 564-37-4

Applications 8-Isoergocornine is an ergot fungus alkaloid related to Ergocornine (E597350). It is a mycotoxin found in moldy food products.
References Sulyok, M., et al.: Anal. Bioanal. Chem., 389, 1505 (2007); Krska, R., et al.: Anal. Bioanal. Chem., 391, 563 (2008); Sulyok, M., et al.: Food Chem., 119, 408 (2009);

Formula: C₃₁H₃₉N₅O₅

Color and Shape: Neat

Molecular weight: 561.67

Ref: TR-I815710