CAS 5649-07-0

(val5)-angiotensin ii acetate

Description:

(val5)-Angiotensin II acetate, with the CAS number 5649-07-0, is a synthetic peptide that is a derivative of angiotensin II, a key regulator in the renin-angiotensin system, which plays a crucial role in blood pressure regulation and fluid balance. This compound is characterized by its specific amino acid sequence, which includes a valine at the fifth position, distinguishing it from other angiotensin II variants. It typically exhibits biological activity by binding to angiotensin receptors, influencing vasoconstriction and aldosterone secretion. The acetate form indicates that it is acetylated, which can enhance its stability and solubility in biological systems. In research and therapeutic contexts, (val5)-angiotensin II acetate is often studied for its potential effects on cardiovascular health and its role in various physiological processes. Its properties, such as solubility, stability, and receptor affinity, make it a valuable compound in pharmacological studies and potential drug development.

Formula: C₄₉H₆₉N₁₃O₁₂

InChI: InChI=1S/C49H69N13O12.C2H4O2/c1-26(2)39(60-42(67)33(12-8-18-54-49(51)52)56-41(66)32(50)23-38(64)65)45(70)57-34(20-29-14-16-31(63)17-15-29)43(68)61-40(27(3)4)46(71)58-35(22-30-24-53-25-55-30)47(72)62-19-9-13-37(62)44(69)59-36(48(73)74)21-28-10-6-5-7-11-28;1-2(3)4/h5-7,10-11,14-17,24-27,32-37,39-40,63H,8-9,12-13,18-23,50H2,1-4H3,(H,53,55)(H,56,66)(H,57,70)(H,58,71)(H,59,69)(H,60,67)(H,61,68)(H,64,65)(H,73,74)(H4,51,52,54);1H3,(H,3,4)/t32-,33-,34-,35-,36-,37-,39-,40-;/m0./s1

InChI key: JVCJXRGXGITABA-IAQGTVMASA-N

SMILES: CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(=O)O)N.CC(=O)O

Synonyms:

• [Val5]-Angiotensin II, Human
• [Val5]-Angiotensin Ii

[Val⁵] Angiotensin II, Human

CAS: 5649-07-0

For cellular and molecular biology applications

Formula: C₄₉H₆₉N₁₃O₁₂

Molecular weight: 1032.15

Ref: 02-J66806

5-L-Valineangiotensin II acetate

CAS: 5649-07-0

5-L-Valineangiotensin II acetate

Formula: C₅₁H₇₃N₁₃O₁₄

Purity: ≥95%

Molecular weight: 1092.2

Ref: 54-OR1135785

5-L-Valineangiotensin II acetate

CAS: 5649-07-0

Purity: 97%

Ref: IN-DA00E9VT

[Val5]-Angiotensin II

CAS: 5649-07-0

Angiotensin II is a peptide hormone that regulates blood pressure and water balance. It is an important component of the renin-angiotensin system, which causes vasoconstriction and release of aldosterone from the adrenal gland. Angiotensin II binds to angiotensin receptors on cells, initiating a second messenger cascade that results in increased blood pressure and electrolyte retention. Val5-Angiotensin II is a synthetic form of this hormone that has been shown to increase glomerular filtration rate by inhibiting angiotensin converting enzyme (ACE). Angiotensin II also stimulates epidermal growth factor, which may be responsible for its anti-inflammatory effects. The optimum pH for Val5-Angiotensin II is between 7.0 and 8.0.

Formula: C₄₉H₆₉N₁₃O₁₂•CH₃COOH•4H₂O

Purity: Min. 95%

Molecular weight: 1,164.31 g/mol

Ref: 3D-PAN-4034