CAS 56602-33-6: BOP reagent

Description: BOP reagent, or benzotriazol-1-yl-oxy-tris(dimethylamino)phosphonium hexafluorophosphate, is a chemical compound commonly used in organic synthesis, particularly in peptide coupling reactions. It serves as a coupling agent that facilitates the formation of amide bonds between carboxylic acids and amines. BOP reagent is characterized by its ability to activate carboxylic acids, making them more reactive towards nucleophilic attack by amines. This reagent is typically favored for its mild reaction conditions and compatibility with various functional groups, which minimizes side reactions. It is a white to off-white solid that is soluble in polar organic solvents. Safety precautions should be observed when handling BOP reagent, as it can be hazardous and may cause irritation. Proper storage in a cool, dry place, away from moisture and incompatible substances, is essential to maintain its stability and effectiveness in synthetic applications.

Formula: C₁₂H₂₂N₆OP·F₆P

InChI: InChI=1S/C12H22N6OP.F6P/c1-15(2)20(16(3)4,17(5)6)19-18-12-10-8-7-9-11(12)13-14-18;1-7(2,3,4,5)6/h7-10H,1-6H3;/q+1;-1

InChI key: InChIKey=MGEVGECQZUIPSV-UHFFFAOYSA-N

SMILES: [F-][P+5]([F-])([F-])([F-])([F-])[F-].N1=NN(O[P+](N(C)C)(N(C)C)N(C)C)C=2C=CC=CC12

Synonyms:

• (1H-benzotriazol-1-yloxy)[tris(dimethylamino)]phosphonium hexafluorophosphate
• (Benzotriazol-1-yloxy)tris(dimethylamino) hexafluorophosphate
• (Boranyloxy)Phosphane
• 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate
• 1H-Benzotriazole, 1-hydroxy-, phosphorus complex
• 2-(1H-Benzotriazol-1-yl)tris(dimethylamino)phosphonium hexafluorophosphate
• BOP
• BOP hexafluorophosphate
• BOP reagent
• Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate
• Benzotriazol-1-yloxytris(dimethylamino)-phosphonium hexafluorophosphate
• Castro reagent
• Castro's reagent
• Le BOP
• Methanamine, N-methyl-, phosphorus complex
• Phosphate(1-), hexafluoro-, (T-4)-(1-hydroxy-1H-benzotriazolato-O)tris(N-methylmethanaminato)phosphorus(1+)
• Phosphorus(1+), (1-hydroxy-1H-benzotriazolato-O)tris(N-methylmethanaminato)-, (T-4)-, hexafluorophosphate(1-)
• Phosphorus(1+), [1-(hydroxy-κO)-1H-benzotriazolato]tris(N-methylmethanaminato)-, (T-4)-, hexafluorophosphate(1-) (1:1)

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate [Coupling Reagent for Peptide]

CAS: 56602-33-6

• Formula: C₁₂H₂₂F₆N₆OP₂
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 442.29

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate, 98%

CAS: 56602-33-6

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate is used as a reagent for peptide coupling, lactonization, selective esterification, amidation of …

• Formula: C₁₂H₂₂F₆N₆OP₂
• Purity: 98%
• Color and Shape: Crystalline powder, White
• Molecular weight: 442.29

(Benzotriazol-1-Yloxy)Tris(Dimethylamino)Phosphonium Hexafluorophosphate

CAS: 56602-33-6

• Formula: C₁₂H₂₂F₆N₆OP₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 442.2806

[(1H-Benzotriazol-1-yl)oxy]tris(dimethylamino)phosphonium hexafluorophosphate

CAS: 56602-33-6

• Formula: C₁₂H₂₂N₆OP·PF₆
• Purity: >98.0% (nmr) (Typical Value in Batch COA)
• Color and Shape: white to off-white solid
• Molecular weight: 442.28g/mol

Benzotriazol-1-yl-oxy-tris(dimethylamino) phosphonium hexafluorophosphate (BOP Reagent)

CAS: 56602-33-6

• Formula: C₁₂H₂₂F₆N₆OP₂
• Molecular weight: 442.29

Benzotriazol-1-yloxytris(dimethylamino)-phosphonium hexafluorophosphate, 98+%

CAS: 56602-33-6

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₂H₂₂F₆N₆OP₂
• Purity: 98+%
• Color and Shape: Powder, White to off-white
• Molecular weight: 442.29

Benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate

CAS: 56602-33-6

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 442.287

BOP Reagent

CAS: 56602-33-6

Please enquire for more information about BOP Reagent including the price, delivery time and more …

• Formula: C₁₂H₂₂N₆OF₆P₂
• Purity: Min. 95%
• Molecular weight: 442.29 g/mol

BOP

CAS: 56602-33-6

BOP, also known with the name of Castro’s reagent, is a phosphonium coupling reagent used …

• Formula: C₁₂H₂₂F₆N₆OP₂
• Purity: Min. 98 Area-%
• Color and Shape: White Off-White Powder
• Molecular weight: 442.28 g/mol

Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate

CAS: 56602-33-6

Applications A peptide coupling reagent. Can be used in the preparation of phenyl esters of …

• Formula: C₁₂H₂₂N₆OP·F₆P
• Color and Shape: Neat
• Molecular weight: 442.28

BOP Reagent extrapure AR, 98%

CAS: 56602-33-6

• Formula: C₁₂H₂₂F₆N₆OP₂
• Purity: min. 98.0%
• Color and Shape: White to pale yellow, Crystalline powder, Crystalline powder
• Molecular weight: 442.29