CAS 568-73-0

Tanshinone I

Description:

Tanshinone I is a bioactive compound primarily derived from the roots of the Salvia miltiorrhiza plant, commonly known as Danshen, which is used in traditional Chinese medicine. It belongs to the class of compounds known as diterpenes and is characterized by its complex polycyclic structure. Tanshinone I exhibits a range of pharmacological properties, including anti-inflammatory, antioxidant, and cardioprotective effects. Its mechanism of action is thought to involve the modulation of various signaling pathways, contributing to its therapeutic potential in cardiovascular diseases and other conditions. The compound is lipophilic, which influences its solubility and bioavailability. Additionally, Tanshinone I has been studied for its potential anticancer properties, showing promise in inhibiting the proliferation of certain cancer cell lines. Due to its diverse biological activities, Tanshinone I is of significant interest in pharmaceutical research and development, particularly in the context of natural product chemistry and drug formulation.

Formula: C₁₈H₁₂O₃

InChI: InChI=1S/C18H12O3/c1-9-4-3-5-12-11(9)6-7-13-15(12)17(20)16(19)14-10(2)8-21-18(13)14/h3-8H,1-2H3

InChI key: InChIKey=AIGAZQPHXLWMOJ-UHFFFAOYSA-N

SMILES: O=C1C=2C(C3=C(C1=O)C(C)=CO3)=CC=C4C2C=CC=C4C

Synonyms:

• 1,6-Dimethyl-phenanthro[1,2-b]furan-10,11-dione
• 1,6-Dimethylphenanthro[1,2-b]furan-10,11-dione
• Phenanthro[1,2-b]furan-10,11-dione, 1,6-dimethyl-
• Tanshinon I
• Tanshinone A
• Tanshinone I

Phenanthro[1,2-b]furan-10,11-dione, 1,6-dimethyl-

CAS: 568-73-0

Formula: C₁₈H₁₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 276.2861

Ref: IN-DA00IA4H

Tanshinone I

CAS: 568-73-0

Tanshinone I

Purity: ≥98%

Molecular weight: 276.29g/mol

Ref: 54-BUP10469

Tanshinone I

CAS: 568-73-0

Tanshinone I

Purity: 99%

Molecular weight: 276.29g/mol

Ref: 54-OR1025997

Tanshinone I

CAS: 568-73-0

Tanshinone I, a major active principle of Salvia miltiorrhiza (Danshen), has been shown to overcome tumor drug resistance and metastasis, it inhibits angiogenesis, inhibits proliferation, migration and tube formation of vascular endothelial cells, rat aortic ring sprouting and the neovascularization of the chick chorioallantoic membrane in a concentration-dependent manner; it as promising angiogenesis inhibitors.

Formula: C₁₈H₁₂O₃

Purity: 95%~99%

Color and Shape: Red powder

Molecular weight: 276.291

Ref: BP-BP1361

Tanshinone I

CAS: 568-73-0

Formula: C₁₈H₁₂O₃

Purity: >95.0%(HPLC)

Color and Shape: Red to Dark red powder to crystal

Molecular weight: 276.29

Ref: 3B-T4153

Tanshinone I

CAS: 568-73-0

Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells.

Formula: C₁₈H₁₂O₃

Purity: 98.31% - 98.70%

Color and Shape: Solid

Molecular weight: 276.29

Ref: TM-T2907

Tanshinone I

CAS: 568-73-0

Formula: C₁₈H₁₂O₃

Molecular weight: 276.29

Ref: 4Z-T-323001

Tanshinone I-d4

CAS: 568-73-0

Formula: C₁₈H₈D₄O₃

Molecular weight: 280.32

Ref: 4Z-T-323003

Tanshinone I

CAS: 568-73-0

Formula: C₁₈H₁₂O₃

Molecular weight: 276.29

Ref: 7W-GP2773

Tanshinone i

CAS: 568-73-0

Oxygen-heterocyclic compound

Formula: C₁₈H₁₂O₃

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 276.29

Ref: 5G-89804

Tanshinone I

CAS: 568-73-0

Tanshinone I is a diterpenoid compound, which is derived from the roots of the traditional Chinese herb Salvia miltiorrhiza, commonly known as Danshen. This bioactive compound exhibits pharmacological actions primarily through its modulatory effects on various biological pathways, including its ability to inhibit the transcription factor NF-κB, resulting in decreased expression of pro-inflammatory cytokines. Additionally, it influences the ROS-mediated pathways, providing protective effects against oxidative stress.

Formula: C₁₈H₁₂O₃

Purity: Min. 95%

Color and Shape: Red Powder

Molecular weight: 276.29 g/mol

Ref: 3D-FT09979

Tanshinone I

CAS: 568-73-0

Formula: C₁₈H₁₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 276.291

Ref: 10-F547220

Tanshinone I

Controlled Product

CAS: 568-73-0

Applications Tanshinone I is an extract from Danshen (Radix Salvia miltiorrhizae) and has been used for the treatment of cerebrovascular diseases such as ischemic stroke.
References Park, J., et. al.: Neurochem. Res., 39, 1300 (2014)

Formula: C₁₈H₁₂O₃

Color and Shape: Neat

Molecular weight: 276.29

Ref: TR-T006990