CAS 568-73-0
:Tanshinone I
Description:
Tanshinone I is a bioactive compound primarily derived from the roots of the Salvia miltiorrhiza plant, commonly known as Danshen, which is used in traditional Chinese medicine. It belongs to the class of compounds known as diterpenes and is characterized by its complex polycyclic structure. Tanshinone I exhibits a range of pharmacological properties, including anti-inflammatory, antioxidant, and cardioprotective effects. Its mechanism of action is thought to involve the modulation of various signaling pathways, contributing to its therapeutic potential in cardiovascular diseases and other conditions. The compound is lipophilic, which influences its solubility and bioavailability. Additionally, Tanshinone I has been studied for its potential anticancer properties, showing promise in inhibiting the proliferation of certain cancer cell lines. Due to its diverse biological activities, Tanshinone I is of significant interest in pharmaceutical research and development, particularly in the context of natural product chemistry and drug formulation.
Formula:C18H12O3
InChI:InChI=1S/C18H12O3/c1-9-4-3-5-12-11(9)6-7-13-15(12)17(20)16(19)14-10(2)8-21-18(13)14/h3-8H,1-2H3
InChI key:InChIKey=AIGAZQPHXLWMOJ-UHFFFAOYSA-N
SMILES:O=C1C=2C(C3=C(C1=O)C(C)=CO3)=CC=C4C2C=CC=C4C
Synonyms:- 1,6-Dimethyl-phenanthro[1,2-b]furan-10,11-dione
- 1,6-Dimethylphenanthro[1,2-b]furan-10,11-dione
- Phenanthro[1,2-b]furan-10,11-dione, 1,6-dimethyl-
- Tanshinon I
- Tanshinone A
- Tanshinone I
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Found 13 products.
Phenanthro[1,2-b]furan-10,11-dione, 1,6-dimethyl-
CAS:Formula:C18H12O3Purity:97%Color and Shape:SolidMolecular weight:276.2861Tanshinone I
CAS:Tanshinone I, a major active principle of Salvia miltiorrhiza (Danshen), has been shown to overcome tumor drug resistance and metastasis, it inhibits angiogenesis, inhibits proliferation, migration and tube formation of vascular endothelial cells, rat aortic ring sprouting and the neovascularization of the chick chorioallantoic membrane in a concentration-dependent manner; it as promising angiogenesis inhibitors.Formula:C18H12O3Purity:95%~99%Color and Shape:Red powderMolecular weight:276.291Tanshinone I
CAS:Formula:C18H12O3Purity:>95.0%(HPLC)Color and Shape:Red to Dark red powder to crystalMolecular weight:276.29Tanshinone I
CAS:Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells.Formula:C18H12O3Purity:98.31% - 98.70%Color and Shape:SolidMolecular weight:276.29Tanshinone i
CAS:Oxygen-heterocyclic compoundFormula:C18H12O3Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:276.29Tanshinone I
CAS:<p>Tanshinone I is a diterpenoid compound, which is derived from the roots of the traditional Chinese herb Salvia miltiorrhiza, commonly known as Danshen. This bioactive compound exhibits pharmacological actions primarily through its modulatory effects on various biological pathways, including its ability to inhibit the transcription factor NF-κB, resulting in decreased expression of pro-inflammatory cytokines. Additionally, it influences the ROS-mediated pathways, providing protective effects against oxidative stress.</p>Formula:C18H12O3Purity:Min. 95%Color and Shape:Red PowderMolecular weight:276.29 g/molTanshinone I
CAS:Controlled Product<p>Applications Tanshinone I is an extract from Danshen (Radix Salvia miltiorrhizae) and has been used for the treatment of cerebrovascular diseases such as ischemic stroke.<br>References Park, J., et. al.: Neurochem. Res., 39, 1300 (2014)<br></p>Formula:C18H12O3Color and Shape:NeatMolecular weight:276.29










