CAS 568565-11-7

L-Alanine,L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-(9CI)

Description:

The chemical substance known as L-Alanine, L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl, with the CAS number 568565-11-7, is a synthetic peptide composed of multiple amino acids. This compound features a sequence that includes L-alanine, L-glutamine, L-arginine, L-proline, L-leucine, L-serine, L-histidine, L-lysine, and L-methionine, indicating its potential role in biological processes or applications in biochemistry. Peptides like this one are often studied for their structural and functional properties, as they can influence various physiological functions, including signaling pathways and metabolic processes. The presence of multiple amino acids suggests that it may exhibit specific biological activities, potentially acting as a signaling molecule or influencing protein synthesis. Additionally, the compound's stability, solubility, and reactivity can vary based on its amino acid composition and sequence, making it a subject of interest in pharmaceutical and biochemical research.

Formula: C₆₃H₁₀₇N₂₃O₁₆S

InChI: InChI=1S/C63H107N23O16S/c1-34(2)28-42(81-52(92)39(13-7-22-72-62(67)68)78-58(98)47-17-11-26-86(47)59(99)40(14-8-23-73-63(69)70)79-50(90)37(65)18-19-48(66)88)53(93)83-44(32-87)55(95)82-43(29-36-30-71-33-75-36)54(94)77-38(12-5-6-21-64)51(91)74-31-49(89)84-24-9-15-45(84)57(97)80-41(20-27-103-4)60(100)85-25-10-16-46(85)56(96)76-35(3)61(101)102/h30,33-35,37-47,87H,5-29,31-32,64-65H2,1-4H3,(H2,66,88)(H,71,75)(H,74,91)(H,76,96)(H,77,94)(H,78,98)(H,79,90)(H,80,97)(H,81,92)(H,82,95)(H,83,93)(H,101,102)(H4,67,68,72)(H4,69,70,73)/t35-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-/m0/s1

InChI key: PZJZONZEQDOQAZ-COFPHXSQSA-N

SMILES: C[C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCSC)NC(=O)[C@@H]2CCCN2C(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CC3=CN=CN3)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N

Synonyms:

• Qrprlshkgpmpa
• [Ala13]-Apelin-13
• (Ala13)-Apelin-13 (Human, Bovine, Mouse, Rat)
• H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-Oh
• [Ala13]Apelin-13, human, bovine, mouse, rat (F13A) (2)
• [Ala13]Apelin 13 (human, mouse, rat, bovine)

(Ala¹³)-Apelin-13 (human, bovine, mouse, rat) (Salt form trifluoroacetate)

CAS: 568565-11-7

Specific anatagonist of apelin-13. Systemic administration of Apelin-13 F13A (30 µg/kg) abolished the blood pressure-lowering effects of apelin-13 (15 µg/kg) in hypertensive rats.

Formula: C₆₃H₁₀₇N₂₃O₁₆S

Purity: > 96%

Color and Shape: White

Molecular weight: 1474.75

Ref: 01-4050032

(Ala¹³)-Apelin-13 (human, bovine, mouse, rat) (Salt form acetate)

CAS: 568565-11-7

(Ala13)-Apelin 13 showed scavenging abilities against active oxygen species such as superoxide and hydroxyl radicals. Apelin-13 F13A could act as an antioxidant that may have a therapeutic effect against diseases (e.g. arthritis and cancer) in which hydroxyl radical damage plays a role.

Formula: C₆₃H₁₀₇N₂₃O₁₆S

Purity: 100%

Color and Shape: White

Molecular weight: 1474.75

Ref: 01-4095877

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH

CAS: 568565-11-7

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH

Formula: C₆₃H₁₀₇N₂₃O₁₆S

Purity: ≥95%

Molecular weight: 1474.73

Ref: 54-OR1113288

(Ala13)-Apelin-13

CAS: 568565-11-7

(Ala13)-Apelin-13 is a useful organic compound for research related to life sciences. The catalog number is T35374 and the CAS number is 568565-11-7.

Formula: C₆₃H₁₀₇N₂₃O₁₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 1474.75

Ref: TM-T35374

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH

CAS: 568565-11-7

Formula: C₆₃H₁₀₇N₂₃O₁₆S

Purity: 95%

Molecular weight: 1474.7332

Ref: IN-DA00EA15

[Ala13]-Apelin-13 trifluoroacetate salt

CAS: 568565-11-7

Apelin-13 is a peptide that is involved in the regulation of locomotor activity and pain. It has been shown to decrease the activity of matrix metalloproteinases, growth factors, and collagen, which are all important for animal development. Apelin-13 also interacts with the factor receptor, which regulates platelet-derived growth. This peptide has been shown to have antinociceptive properties and can be used in a pain model. Apelin-13 also interacts with the cb2 receptor, which may regulate inflammation.

Formula: C₆₃H₁₀₇N₂₃O₁₆S·xC₂HF₃O₂

Purity: Min. 95%

Ref: 3D-TXA56511

(Ala13)-Apelin-13 (human, bovine, mouse, rat) acetate salt

CAS: 568565-11-7

Apelin-13 is a peptide hormone that is secreted from the stomach and small intestine. It may have analgesic effects through its interaction with μ-opioid receptors, which are also activated by morphine. Apelin-13 has been shown to increase locomotor activity in rats, suggesting it can potentiate the antinociceptive effect of morphine.

Formula: C₆₃H₁₀₇N₂₃O₁₆S·xC₂H₄O₂

Purity: Min. 95%

Molecular weight: 1,474.74 g/mol

Ref: 3D-FA110249