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CAS 569-65-3

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Meclizine

Description:
Meclizine is an antihistamine commonly used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness and vertigo. It belongs to the piperazine class of compounds and functions primarily as an H1 receptor antagonist. The chemical formula for Meclizine is C16H26ClN, and it has a molecular weight of approximately 285.84 g/mol. Meclizine is characterized by its ability to cross the blood-brain barrier, which contributes to its sedative effects. It is typically administered orally and is available in various formulations, including tablets and chewable forms. The substance exhibits a moderate lipophilicity, which aids in its absorption and distribution in the body. Common side effects may include drowsiness, dry mouth, and blurred vision. Due to its sedative properties, caution is advised when operating machinery or driving after taking Meclizine. Overall, it is a well-established medication in the management of motion-related ailments.
Formula:C25H27ClN2
InChI:InChI=1/C25H27ClN2/c1-20-6-5-7-21(18-20)19-27-14-16-28(17-15-27)25(22-8-3-2-4-9-22)23-10-12-24(26)13-11-23/h2-13,18,25H,14-17,19H2,1H3
InChI key:InChIKey=OCJYIGYOJCODJL-UHFFFAOYSA-N
SMILES:C(N1CCN(CC2=CC(C)=CC=C2)CC1)(C3=CC=C(Cl)C=C3)C4=CC=CC=C4
Synonyms:
  • (.+-.)-Meclizine
  • 1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl) piperazine
  • 1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)diethylenediamine
  • 1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)piperazine
  • 1-(p-Chlorobenzohydryl)-4-(m-methylbenzyl) piperazine
  • 1-[(4-Chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine hydrate
  • 1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine
  • Ancolan
  • Bonine
  • Histametizyne
  • See more synonyms
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