CAS 569-65-3

Meclizine

Description:

Meclizine is an antihistamine commonly used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness and vertigo. It belongs to the piperazine class of compounds and functions primarily as an H1 receptor antagonist. The chemical formula for Meclizine is C16H26ClN, and it has a molecular weight of approximately 285.84 g/mol. Meclizine is characterized by its ability to cross the blood-brain barrier, which contributes to its sedative effects. It is typically administered orally and is available in various formulations, including tablets and chewable forms. The substance exhibits a moderate lipophilicity, which aids in its absorption and distribution in the body. Common side effects may include drowsiness, dry mouth, and blurred vision. Due to its sedative properties, caution is advised when operating machinery or driving after taking Meclizine. Overall, it is a well-established medication in the management of motion-related ailments.

Formula: C₂₅H₂₇ClN₂

InChI: InChI=1/C25H27ClN2/c1-20-6-5-7-21(18-20)19-27-14-16-28(17-15-27)25(22-8-3-2-4-9-22)23-10-12-24(26)13-11-23/h2-13,18,25H,14-17,19H2,1H3

InChI key: InChIKey=OCJYIGYOJCODJL-UHFFFAOYSA-N

SMILES: C(N1CCN(CC2=CC(C)=CC=C2)CC1)(C3=CC=C(Cl)C=C3)C4=CC=CC=C4

Synonyms:

• (.+-.)-Meclizine
• 1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl) piperazine
• 1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)diethylenediamine
• 1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)piperazine
• 1-(p-Chlorobenzohydryl)-4-(m-methylbenzyl) piperazine
• 1-[(4-Chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine hydrate
• 1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine
• Ancolan
• Bonine
• Histametizyne
• Meclozin
• Meclozina
• Meclozine
• Navicalm
• Neo-Istafene
• Nsc 169189
• Parachloramine
• Piperazine, 1-(p-chloro-α-phenylbenzyl)-4-(m-methylbenzyl)-
• Postafene
• Ravelon
• Sabari
• Suprimal
• U.C.B. 5062
• Vomisseis
• Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-
• Histamethizine
• 1-[(4-Chlorophenyl)(phenyl)methyl]-4-(3-methylbenzyl)piperazine
• Histamethine
• Calmonal
• Chiclida
• Marex
• Histametizine
• 1-[(4-chlorophenyl)-phenyl-methyl]-4-[(3-methylphenyl)methyl]piperazine
• Ancolon
• Bonadettes
• Bonadoxin
• Itinerol

1-[(4-chlorophenyl)(phenyl)methyl]-4-[(3-methylphenyl)methyl]piperazine

CAS: 569-65-3

Formula: C₂₅H₂₇ClN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 390.9483

Ref: IN-DA00IA5E

Meclizine

CAS: 569-65-3

Meclizine

Purity: ≥95%

Molecular weight: 390.95g/mol

Ref: 54-BUP01690

Meclizine-d8

CAS: 569-65-3

Formula: C₂₅H₁₉ClN₂D₈

Molecular weight: 398.99

Ref: 4Z-M-402

Meclozine

CAS: 569-65-3

Formula: C₂₅H₂₇ClN₂

Molecular weight: 390.96

Ref: 4Z-M-102001

Meclizine

CAS: 569-65-3

Meclizine, also known as Meclozine, is a piperazine class H1 antagonist with antihistamine properties that inhibits the interaction of histamine at H1 receptors

Formula: C₂₅H₂₇ClN₂

Purity: 99.55%

Color and Shape: Solid

Molecular weight: 390.95

Ref: TM-T40652