CAS 569-65-3: Meclizine

Description: Meclizine is an antihistamine commonly used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness and vertigo. It belongs to the piperazine class of compounds and functions primarily as an H1 receptor antagonist. The chemical formula for Meclizine is C16H26ClN, and it has a molecular weight of approximately 285.84 g/mol. Meclizine is characterized by its ability to cross the blood-brain barrier, which contributes to its sedative effects. It is typically administered orally and is available in various formulations, including tablets and chewable forms. The substance exhibits a moderate lipophilicity, which aids in its absorption and distribution in the body. Common side effects may include drowsiness, dry mouth, and blurred vision. Due to its sedative properties, caution is advised when operating machinery or driving after taking Meclizine. Overall, it is a well-established medication in the management of motion-related ailments.

Formula: C₂₅H₂₇ClN₂

InChI: InChI=1S/C25H27ClN2/c1-20-6-5-7-21(18-20)19-27-14-16-28(17-15-27)25(22-8-3-2-4-9-22)23-10-12-24(26)13-11-23/h2-13,18,25H,14-17,19H2,1H3

InChI key: InChIKey=OCJYIGYOJCODJL-UHFFFAOYSA-N

SMILES: ClC1=CC=C(C=C1)C(C=2C=CC=CC2)N3CCN(CC=4C=CC=C(C4)C)CC3

Synonyms:

• (.+-.)-Meclizine
• 1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl) piperazine
• 1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)diethylenediamine
• 1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)piperazine
• 1-(p-Chlorobenzohydryl)-4-(m-methylbenzyl) piperazine
• 1-[(4-Chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine hydrate
• 1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine
• Ancolan
• Bonine
• Histametizyne
• Meclozin
• Meclozina
• Meclozine
• Navicalm
• Neo-Istafene
• Nsc 169189
• Parachloramine
• Piperazine, 1-(p-chloro-α-phenylbenzyl)-4-(m-methylbenzyl)-
• Postafene
• Ravelon
• Sabari
• Suprimal
• U.C.B. 5062
• Vomisseis
• Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-

Piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-

CAS: 569-65-3

• Formula: C₂₅H₂₇ClN₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 390.9483

Meclizine

CAS: 569-65-3

• Purity: 95.16%
• Molecular weight: 390.95g/mol

Meclizine

CAS: 569-65-3

Meclizine, also known as Meclozine, is a piperazine class H1 antagonist with antihistamine properties that …

• Formula: C₂₅H₂₇ClN₂
• Purity: 95.16%
• Color and Shape: Solid
• Molecular weight: 390.95

Meclozine

CAS: 569-65-3

• Formula: C₂₅H₂₇ClN₂
• Molecular weight: 390.96

Meclizine-d8

CAS: 569-65-3

• Formula: C₂₅H₁₉ClN₂D₈
• Molecular weight: 398.99

Meclizine Dihydrochloride

CAS: 1104-22-9 569-65-3

• Formula: C₂₅H₂₇ClN₂·2HCl
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 463.87

Meclozine

CAS: 569-65-3

Meclozine is a nonsteroidal anti-inflammatory drug used to treat pain, stiffness and swelling in adults. …

• Formula: C₂₅H₂₇ClN₂
• Purity: Min. 95%
• Molecular weight: 390.95 g/mol