CAS 57103-68-1

11-chloro-6,21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaene-8,23-dione

Description:

The chemical substance known as "11-chloro-6,21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaene-8,23-dione" with CAS number 57103-68-1 is a complex organic compound characterized by its intricate tetracyclic structure and multiple functional groups. It features a combination of hydroxyl (-OH), methoxy (-OCH3), and chloro (-Cl) substituents, contributing to its reactivity and potential biological activity. The presence of multiple double bonds indicates that it may exhibit significant conjugation, which can influence its optical properties and stability. The compound's unique structural features suggest potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. However, due to its complexity, detailed studies on its synthesis, stability, and biological interactions are essential for understanding its full potential and safety profile. As with many specialized compounds, handling and usage should be approached with caution, adhering to appropriate safety guidelines.

Formula: C₂₈H₃₇ClN₂O₈

InChI: InChI=1/C28H37ClN2O8/c1-15-8-7-9-22(37-6)28(35)14-20(38-26(34)30-28)16(2)25-27(3,39-25)21(32)13-23(33)31(4)18-11-17(10-15)12-19(36-5)24(18)29/h7-9,11-12,16,20-22,25,32,35H,10,13-14H2,1-6H3,(H,30,34)/b9-7+,15-8-

Synonyms:

• Maytansine, O3-de2-(acetylmethylamino)-1-oxopropyl-
• Maytansinol

Maytansinol

CAS: 57103-68-1

Formula: C₂₈H₃₇ClN₂O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 565.0550

Ref: IN-DA00354O

Maytansinol

CAS: 57103-68-1

Maytansinol (Ansamitocin P-0) inhibits microtubule assembly and causes microtubule disassembly in vitro.

Formula: C₂₈H₃₇ClN₂O₈

Purity: 98.80% - 99.71%

Color and Shape: Solid

Molecular weight: 565.05

Ref: TM-T16016

Maytansinol

CAS: 57103-68-1

Maytansinol

Purity: ≥98%

Molecular weight: 565.05g/mol

Ref: 54-BUP12902

Maytansinol

CAS: 57103-68-1

Formula: C₂₈H₃₇ClN₂O₈

Purity: 95%~99%

Molecular weight: 565.06

Ref: BP-BP4607

Maytansinol

CAS: 57103-68-1

Formula: C₂₈H₃₇ClN₂O₈

Molecular weight: 565.06

Ref: 4Z-M-243001

Maytansinol

CAS: 57103-68-1

Maytansinol is a molecule that has potent antitumor activity. It has been shown to be effective against leukemia cells, and inhibits the growth of cells in culture by binding to the lymphatic vessels. Maytansinol is also able to bind to metal ions and forms a chelate complex with them. The effective dose of maytansinol is 3-5mg/kg body weight, which can be administered orally or intravenously. The drug has been shown to have an activity test using genus monoclonal antibody (Mab). Maytansinol hydrolyzes at alkaline pH and reacts with hydroxy groups in its structure.

Formula: C₂₈H₃₇ClN₂O₈

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 565.05 g/mol

Ref: 3D-FM44850

Maytansinol

CAS: 57103-68-1

Applications Maytansinol is used in the preparation of site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity.
References Pillow, T.H., et. al.: J. Med. Chem., 57, 7890 (2014)

Formula: C₂₈H₃₇ClN₂O₈

Color and Shape: Neat

Molecular weight: 565.05

Ref: TR-M197950