CAS 5714-08-9

D-Triiodothyronine

Description:

D-Triiodothyronine, commonly known as T3, is a thyroid hormone that plays a crucial role in regulating metabolism, growth, and development in the body. It is a derivative of thyroxine (T4) and contains three iodine atoms, which are essential for its biological activity. T3 is synthesized in the thyroid gland and is more potent than T4, influencing various physiological processes, including heart rate, body temperature, and energy expenditure. The chemical structure of D-Triiodothyronine includes a phenolic ring and an amine group, contributing to its solubility in lipids and its ability to cross cell membranes. T3 exerts its effects primarily by binding to nuclear receptors, leading to the modulation of gene expression. Its levels in the bloodstream are tightly regulated by feedback mechanisms involving the hypothalamus and pituitary gland. Abnormal levels of T3 can lead to various health issues, including hyperthyroidism or hypothyroidism, highlighting its importance in endocrine function and overall metabolic health.

Formula: C₁₅H₁₂I₃NO₄

InChI: InChI=1/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m1/s1

InChI key: InChIKey=AUYYCJSJGJYCDS-GFCCVEGCSA-N

SMILES: O(C1=C(I)C=C(C[C@H](C(O)=O)N)C=C1I)C2=CC(I)=C(O)C=C2

Synonyms:

• (+)-Triiodothyronine
• 3,3′,5-Triiodo-<span class="text-smallcaps">D</span>-thyronine
• 3,5,3′-<span class="text-smallcaps">D</span>-Triiodothyronine
• 3,5,3′-Triiodo-<span class="text-smallcaps">D</span>-thyronine
• <span class="text-smallcaps">D</span>-3,5,3′-Triiodothyronine
• <span class="text-smallcaps">D</span>-Triiodothyronin
• <span class="text-smallcaps">D</span>-Triiodothyronine
• <span class="text-smallcaps">D</span>-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-
• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, <span class="text-smallcaps">D</span>-
• Detrothyronin
• Detrothyronine
• Dextrothyronine
• Dextrotriiodothyronine
• NSC 46046
• O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-<span class="text-smallcaps">D</span>-tyrosine
• O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-D-tyrosine
• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, D-
• DT 3
• D-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-
• D-Triiodothyronin
• D-3,5,3'-Triiodothyronine
• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, D- (8CI)
• D-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo- (9CI)
• Iodine ronin sodium
• 3,5,3'-D-Triiodothyronine
• D-Triiodothyronine

Detrothyronine

CAS: 5714-08-9

Detrothyronine is a biochemical.

Formula: C₁₅H₁₂I₃NO₄

Color and Shape: Solid

Molecular weight: 650.97

Ref: TM-T31393

Liothyronine related impurity, (R)-2-amino

CAS: 5714-08-9

Formula: C₁₅H₁₂I₃NO₄

Molecular weight: 650.98

Ref: 4Z-T-4215

3,3’,5-Triiodo-D-thyronine

Controlled Product

CAS: 5714-08-9

Applications 3,3’,5-Triiodo-D-thyronine is a structural analogue o the thyroid homonef Thyroxine (T425600). 3,3’,5-Triiodo-D-thyronine has been shown to reduce cholesterol in blood serum.
References Mintz, D.O., et. al.: New Engl. J. Med., 266, 808 (1962)

Formula: C₁₅H₁₂I₃NO₄

Color and Shape: Off-White To Light Brown

Molecular weight: 650.97

Ref: TR-T795375

3,3’,5-Triiodo-D-thyronine

CAS: 5714-08-9

Formula: C₁₅H₁₂I₃NO₄

Molecular weight: 651

Ref: ST-EA-CP-L18056

Liothyronine R-Isomer

CAS: 5714-08-9

Formula: C₁₅H₁₂I₃NO₄

Molecular weight: 650.98

Ref: ST-EA-CP-L45016

3,3',5'-Triiodo-D-thyronine

CAS: 5714-08-9

3,3',5'-Triiodo-D-thyronine is a thyroid hormone that is used in the treatment of hypothyroidism. It is administered by injection or by mouth. 3,3',5'-Triiodo-D-thyronine is an insoluble drug, which means it cannot be dissolved in water. This drug can be injected into the body or taken as a pill. 3,3',5'-Triiodo-D-thyronine has been shown to increase metabolic rate and may also inhibit the growth of certain types of tumors. 3,3',5'-Triiodo-D-thyronine has been used in diagnostic procedures such as iontophoresis and implanting devices to treat prostate cancer. This medication can also be used for cosmetic purposes such as skin rejuvenation and hair loss prevention. 3,3',5'-Triiodo-D-thyronine has two structural isomers: levothyroxine and

Formula: C₁₅H₁₂I₃NO₄

Purity: Min. 95%

Molecular weight: 650.97 g/mol

Ref: 3D-FT176266