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CAS 57149-07-2

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Naftopidil

Description:
Naftopidil is a pharmaceutical compound primarily used as an antihypertensive agent, particularly in the treatment of benign prostatic hyperplasia (BPH). It functions as an alpha-1 adrenergic receptor antagonist, which helps to relax smooth muscle in the prostate and bladder neck, thereby improving urinary flow. Naftopidil is characterized by its selective action on the alpha-1A subtype of adrenergic receptors, which contributes to its efficacy and reduced side effects compared to non-selective alpha blockers. The compound is typically administered orally and is known for its relatively favorable safety profile. In terms of chemical properties, Naftopidil has a molecular formula that includes carbon, hydrogen, nitrogen, and oxygen, and it exhibits moderate solubility in water. Its pharmacokinetics involve absorption, metabolism, and excretion processes that are important for its therapeutic effects. Overall, Naftopidil represents a significant option in managing conditions related to urinary obstruction due to prostate enlargement.
Formula:C24H28N2O3
InChI:InChI=1S/C24H28N2O3/c1-28-24-11-5-4-10-22(24)26-15-13-25(14-16-26)17-20(27)18-29-23-12-6-8-19-7-2-3-9-21(19)23/h2-12,20,27H,13-18H2,1H3
InChI key:InChIKey=HRRBJVNMSRJFHQ-UHFFFAOYSA-N
SMILES:O(CC(CN1CCN(CC1)C2=C(OC)C=CC=C2)O)C=3C4=C(C=CC3)C=CC=C4
Synonyms:
  • 1-Piperazineethanol, 4-(2-methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-
  • 1-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-(naphthalen-1-yloxy)-propan-2-ol
  • 1-[4-(2-Methoxyphenyl)Piperazin-1-Yl]-3-(Naphthalen-1-Yloxy)Propan-2-Ol
  • 1-[4-(2-Methoxyphenyl)Piperazin-1-Yl]-3-(Naphthalen-1-Yloxy)Propan-2-Ol Dihydrochloride
  • 1-[4-(2-Methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol
  • 3-[4-(2-Methoxyphenyl)piperazinyl]-1-naphthyloxypropan-2-ol
  • 4-(2-Methoxyphenyl)-a-[(1-naphthalenyloxy)methyl]-1-piperazineethanol dihydrochloride
  • 4-(2-Methoxyphenyl)-alpha-[(1-naphthalenyloxy)methyl]-1-piperazineethanol dihydrochloride
  • 4-(2-Methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-1-piperazineethanol
  • Avishot
  • See more synonyms
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100
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50
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90
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95
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100
Found 17 products.