CAS 57294-38-9

n-tert-Butoxycarbonyl-gamma-aminobutyric acid

Description:

n-tert-Butoxycarbonyl-gamma-aminobutyric acid, commonly referred to as Boc-GABA, is an amino acid derivative characterized by the presence of a tert-butoxycarbonyl (Boc) protecting group attached to the gamma position of the aminobutyric acid structure. This compound is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethyl sulfoxide, but less soluble in water. The Boc group serves as a protective moiety for the amino group, facilitating its use in peptide synthesis and other organic reactions by preventing unwanted side reactions. Boc-GABA is often utilized in the synthesis of pharmaceuticals and biologically active compounds due to its ability to enhance the stability and solubility of the amino acid during chemical transformations. Additionally, it can be deprotected under mild acidic conditions, allowing for the regeneration of the free amino group for further functionalization. Its unique structure and properties make it a valuable intermediate in medicinal chemistry and peptide synthesis.

Formula: C₉H₁₇NO₄

InChI: InChI=1/C9H17NO4/c1-9(2,3)14-8(13)10-6-4-5-7(11)12/h4-6H2,1-3H3,(H,10,13)(H,11,12)/p-1

SMILES: CC(C)(C)OC(=NCCCC(=O)[O-])O

Synonyms:

• gamma-(Boc-amino)butyric acid
• Boc-G-Abu-OH
• Butoxycarbonylaminobutyricacid
• Boc-GABA-OH
• Boc-Gamma-Abu-Oh
• 4-[(Tert-Butoxycarbonyl)Amino]Butanoic Acid
• 4-[(Tert-Butoxycarbonyl)Amino]Butanoate
• Boc-Gama-Abu-OH
• Fmoc-Arg(No2)
• BOC-L-4-AMINOBUTYRIC ACID
• BOC-4-AMINOBUTANOIC ACID
• BOC-L-GAMMA-AMINOBUTYRIC ACID
• 4-N-(TERT-BUTOXYCARBONYL)AMINOBUTYRIC ACID
• 4-TERT-BUTOXYCARBONYLAMINOBUTYRIC ACID
• BOC-GAMMA-AMINOBUTYRIC ACID
• N-TERT-BUTOXYCARBONYL-GAMMA-AMINOBUTYRIC ACID
• N-T-BUTOXYCARBONYL-L-4-AMINOBUTYRIC ACID
• BOC-ABU(4)-OH
• BOC-NH-(CH2)3-COOH
• N-BOC-GAMMA-AMINOBUTYRIC ACID
• BOC-4-AMINOBUTYRIC ACID
• 4-(BOC-AMINO)BUTYRIC ACID
• N-BOC-4-AMINO BUTYRIC ACID
• BOC-GABA
• BOC-4-ABU-OH

N-(tert-Butoxycarbonyl)-4-aminobutyric Acid

CAS: 57294-38-9

Formula: C₉H₁₇NO₄

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 203.24

Ref: 3B-B4291

N-Boc-γ-aminobutyric acid, 98+%

CAS: 57294-38-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₁₇NO₄

Purity: 98+%

Color and Shape: White to pale cream, Crystals or powder or crystalline powder

Molecular weight: 203.24

Ref: 02-B22407

4-(tert-Butyloxycarbonylamino)butanoic acid

CAS: 57294-38-9

Formula: C₉H₁₇NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 203.2356

Ref: IN-DA0035CY

Boc-GABA-OH

CAS: 57294-38-9

Boc-GABA-OH

Formula: C₉H₁₇NO₄

Purity: ≥98%

Molecular weight: 203.24

Ref: 54-BUP19653

4-(tert-Butoxycarbonylamino)butyric acid

CAS: 57294-38-9

4-(tert-Butoxycarbonylamino)butyric acid

Formula: C₉H₁₇NO₄

Purity: >98%

Molecular weight: 203.23558

Ref: 54-OR322021

Boc-GABA-OH

CAS: 57294-38-9

Formula: (CH₃)₃COCONH(CH₂)₃CO₂H

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 203.24

Ref: 7W-GM8484

Boc-GABA-OH

CAS: 57294-38-9

Boc-GABA-OH serves as a PROTAC linker essential for synthesizing UNC6852, an EED-targeted PROTAC[1].

Formula: C₉H₁₇NO₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 203.24

Ref: TM-T17649

N-Boc-γ-aminobutyric Acid

Controlled Product

CAS: 57294-38-9

Formula: C₉H₁₇NO₄

Color and Shape: Neat

Molecular weight: 203.24

Ref: TR-N656140

Boc-γ-Abu-OH

CAS: 57294-38-9

Boc-γ-Abu-OH is a model drug used in peptide synthesis. It is a building block that can be used to form the amino acid γ-Abu. This amino acid has an unusual β-amino group, which is coupled with the Boc group using photorelease chemistry. The resulting compound can be used as a building block for dendrimer or convergent syntheses.
Boc-γ-Abu-OH reacts with dimethoxybenzene and dendron to form γ-Abu. The resulting product can be reacted with other molecules, such as diamines and benzyl halides, to produce analogues of γ-Abu. This process allows for the synthesis of new compounds that have not been previously reported in the literature.

Formula: C₉H₁₇NO₄

Purity: Min. 95%

Molecular weight: 203.24 g/mol

Ref: 3D-BAB-5363-PI

4-tert-Butoxycarbonylaminobutyric acid

CAS: 57294-38-9

Formula: C₉H₁₇NO₄

Purity: 97%

Color and Shape: Crystalline Powder,Powder

Molecular weight: 203.238

Ref: 10-F019573

N-Boc-γ-aminobutyric acid

CAS: 57294-38-9

Boc-GABA-OH

Formula: C₉H₁₇NO₄

Purity: 97%

Molecular weight: 203.24

Ref: IN-DG7092

Boc-γ-Abu-OH

CAS: 57294-38-9

Bachem ID: 4007074.

Formula: C₉H₁₇NO₄

Purity: > 99%

Color and Shape: White

Molecular weight: 203.24

Ref: 01-4007074