CAS 57327-90-9

(Tyr0)-C-Peptide (Human)

Description:

(Tyr0)-C-Peptide (Human), with the CAS number 57327-90-9, is a peptide that plays a significant role in the regulation of insulin secretion and is a marker for pancreatic beta-cell function. This peptide is derived from proinsulin and is released into the bloodstream in equimolar amounts with insulin. Its structure includes a sequence of amino acids that contribute to its biological activity, particularly in the context of glucose metabolism. The presence of the tyrosine residue at the N-terminus is crucial for its stability and interaction with receptors. (Tyr0)-C-Peptide is often measured in clinical settings to assess insulin production and can provide insights into conditions such as diabetes. It is generally stable under physiological conditions, but its levels can be influenced by various factors, including metabolic state and hormonal regulation. Overall, (Tyr0)-C-Peptide serves as an important biomarker in endocrinology and metabolic research.

Formula: C₁₃₈H₂₂₀N₃₆O₅₀

Synonyms:

• ProinsulinC-peptide (human), N-L-tyrosyl-
• Proinsulin connecting peptide (human),1-de-L-arginine-2-L-tyrosine-34-de-L-lysine-35-de-L-arginine-
• 304: PN: US20090175821 SEQID: 378claimed protein
• Proinsulin C-peptide [tyrosyl] (human)
• L-Glutamine,L-tyrosyl-L-a-glutamyl-L-alanyl-L-a-glutamyl-L-a-aspartyl-L-leucyl-L-glutaminyl-L-valylglycyl-L-glutaminyl-L-valyl-L-a-glutamyl-L-leucylglycylglycylglycyl-L-prolylglycyl-L-alanylglycyl-L-seryl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L
• 199: PN:WO0069900 SEQID: 378 unclaimed sequence
• [Tyr0]-C-Peptide
• C-PEPTIDE, HUMAN, (TYR0)
• H-TYR-GLU-ALA-GLU-ASP-LEU-GLN-VAL-GLY-GLN-VAL-GLU-LEU-GLY-GLY-GLY-PRO-GLY-ALA-GLY-SER-LEU-GLN-PRO-LEU-ALA-LEU-GLU-GLY-SER-LEU-GLN-OH
• TYR-GLU-ALA-GLU-ASP-LEU-GLN-VAL-GLY-GLN-VAL-GLU-LEU-GLY-GLY-GLY-PRO-GLY-ALA-GLY-SER-LEU-GLN-PRO-LEU-ALA-LEU-GLU-GLY-SER-LEU-GLN
• (TYR0)-C-PEPTIDE (HUMAN)
• L-Glutamine, L-tyrosyl-L-α-glutamyl-L-alanyl-L-α-glutamyl-L-α-aspartyl-L-leucyl-L-glutaminyl-L-valylglycyl-L-glutaminyl-L-valyl-L-α-glutamyl-L-leucylglycylglycylglycyl-L-prolylglycyl-L-alanylglycyl-L-seryl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-L-α-glutamylglycyl-L-seryl-L-leucyl-
• [TYRO]-C-PEPTIDE, HUMAN
• C-PEPTIDE

(Tyr⁰)-C-Peptide (human)

CAS: 57327-90-9

C-Peptide derivative for radioimmunoassay.

Formula: C₁₃₈H₂₂₀N₃₆O₅₀

Purity: > 94%

Molecular weight: 3183.48

Ref: 01-4034546

[Tyr0]-C-Peptide (Human)

CAS: 57327-90-9

This product is a C-peptide derivative for use in radioimmunoassays. C-peptide is a peptide hormone that is cleaved from proinsulin in the pancreatic beta cells. During glycaemia C-peptide alongside insulin are released by the beta cells. Interestingly C-peptide is not immediately metabolised by the liver and it also has a relatively long half life compared to insulin. Therefore it can be a useful biomarker to monitor beta cell function. Increased levels of C-peptide occurring in patients with insulin resistant type 2 diabetes mellitus, have been associated with macrovascular complications and cardiovascular morbidity. Furthermore C-peptide has been found to prevent endothelial cell reactive oxygen species from being formed thus reducing oxidative stress. This also may lead to anti-inflammatory and anti-apoptotic responses.

Formula: C₁₃₈H₂₂₀N₃₆O₅₀

Purity: Min. 95%

Molecular weight: 3,183.5 g/mol

Ref: 3D-PCP-3724-PI

(Tyr0)-C-Peptide (human)

CAS: 57327-90-9

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Formula: C₁₃₈H₂₂₀N₃₆O₅₀

Purity: Min. 95%

Molecular weight: 3,183.44 g/mol

Ref: 3D-FT109409